Results 31 to 40 of about 62,280 (291)

Purinergic Dysfunction and Electrolyte Imbalance in Newly Diagnosed Bipolar Disorder Patients: A Case-control Study [PDF]

open access: yesIndian Journal of Medical Biochemistry
Aim and background: Patients with bipolar disorder experience alternating episodes of mania and depression. Adenosine, a purinergic base, plays a critical role in regulating mood, sleep, activity, appetite, cognition, memory, seizure threshold, social ...
Gayathri Ponnusamy, C Mythili
doaj   +1 more source

Partial purification of adenosine deaminase from protoscoleces of Echinococcus granulosus [PDF]

open access: yesKirkuk Journal of Science, 2015
Adenosine deaminase has been partially purified from protoscoleces of E. granulosus by gel filtration chromatography using Sephadex G100. The molecular weight of the enzyme determined by gel filtration was about 44000 dalton with specific activity ...
Husain F. Hassan, Inas I. Rasheed
doaj   +1 more source

Disinhibition of hippocampal CA3 neurons induced by suppression of an adenosine A1 receptor-mediated inhibitory tonus: Pre- and postsynaptic components [PDF]

open access: yes, 1993
Intracellular recordings were performed on hippocampal CA3 neuronsin vitro to investigate the inhibitory tonus generated by endogenously produced adenosine in this brain region.
Alzheimer   +60 more
core   +1 more source

Adenosine deaminase, (ADA) level in leprosy

open access: yesInternational Journal of Medicine and Health Development, 2012
Background: Adenosine deaminase (ADA) is involved in and the catabolism of toxic de-oxynucleotides (5) and modulation of insulin action. Although its activities in leprosy have been measured, its characteristics have not been reported.
I S I Ogbu, I N Nnatuanya, J C Onyeanusi
doaj   +1 more source

CoCl2-Mimicked Endothelial Cell Hypoxia Induces Nucleotide Depletion and Functional Impairment That Is Reversed by Nucleotide Precursors

open access: yesBiomedicines, 2022
Chronic hypoxia drives vascular dysfunction by various mechanisms, including changes in mitochondrial respiration. Although endothelial cells (ECs) rely predominantly on glycolysis, hypoxia is known to alter oxidative phosphorylation, promote oxidative ...
Barbara Kutryb-Zajac   +6 more
doaj   +1 more source

L-Arginine Intake Effect on Adenine Nucleotide Metabolism in Rat Parenchymal and Reproductive Tissues

open access: yesThe Scientific World Journal, 2012
L-arginine is conditionally essetcial amino acid, required for normal cell growth, protein synthesis, ammonia detoxification, tissue growth and general performance, proposed in the treatment of men sterility and prevention of male impotence.
G. Kocic   +8 more
doaj   +1 more source

The Diagnostic Efficacy of Adenosine Deaminase in Tubercular Effusion

open access: yesOman Medical Journal, 2013
Objective: This study aims to evaluate the diagnostic efficacy of adenosine deaminase in tubercular effusions.Methods: This study was conducted at the Department of General Medicine and Cardiovascular and Thoracic Surgery, SKIMS, for a period of two ...
Mohd Arif Kelam   +6 more
doaj   +1 more source

Immunological diagnosis as an adjunctive tool for an early diagnosis of tuberculous meningitis of an immune competent child in a low tuberculosis endemic country: A case report [PDF]

open access: yes, 2017
Background: Pediatric tuberculous meningitis is a highly morbid, often fatal disease. Its prompt diagnosis and treat - ment saves lives, in fact delays in the initiation of therapy have been associated with high mortality rates. Case presentation:
Ajassa, Camilla   +12 more
core   +4 more sources

Dosagem da atividade da adenosina deaminase no líquido pleural para o diagnóstico da tuberculose pleural Pleural fluid adenosine deaminase detection for the diagnosis of pleural tuberculosis

open access: yesJornal Brasileiro de Pneumologia, 2004
INTRODUÇÃO: O diagnóstico da tuberculose pleural permanece um desafio, pois a sensibilidade dos testes tradicionais é baixa. O exame histopatológico da pleura é o método mais preciso, com até 80% de sensibilidade.
Morrys Casagrande Kaisemann   +3 more
doaj   +1 more source

New insights into the biological role of mammalian ADARs; the RNA editing proteins [PDF]

open access: yes, 2015
The ADAR proteins deaminate adenosine to inosine in double-stranded RNA which is one of the most abundant modifications present in mammalian RNA.
Arieti, Fabiana   +4 more
core   +2 more sources

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