Results 31 to 40 of about 215,850 (301)
Adenosine Deaminase 2 Deficiency
Definitions, 2020 Inflammation is a normal immune system response to injury and foreign invaders (such as bacteria). However, ADA2 deficiency causes abnormal, unprovoked inflammation that can damage the body's tissues and organs, particularly blood vessels. ( Inflammation
semanticscholar +1 more source
Medicine Science, 2014 A few prospective studies evaluated the oxidative stress variables and adenosine deaminase activity in patients with hyperthyroidism and hypothyroidism. Thus; we aimed to investigate oxidative stress variables and adenosine deaminase activity in patients
Tugba Raika Kiran +3 more
doaj +1 more source
Expanded base editing in rice and wheat using a Cas9-adenosine deaminase fusion
Genome Biology, 2018 Nucleotide base editors in plants have been limited to conversion of cytosine to thymine. Here, we describe a new plant adenine base editor based on an evolved tRNA adenosine deaminase fused to the nickase CRISPR/Cas9, enabling A•T to G•C conversion at ...
C. Li +7 more
semanticscholar +1 more source
Clinics, 2016 OBJECTIVES: Delay in the treatment of pleural infection may contribute to its high mortality. In this retrospective study, we aimed to evaluate the diagnostic accuracy of pleural adenosine deaminase in discrimination between Gram-negative and Gram ...
Ruolin Li +3 more
doaj +1 more source
Partial purification of adenosine deaminase from protoscoleces of Echinococcus granulosus [PDF]
Kirkuk Journal of Science, 2015 Adenosine deaminase has been partially purified from protoscoleces of E. granulosus by gel filtration chromatography using Sephadex G100. The molecular weight of the enzyme determined by gel filtration was about 44000 dalton with specific activity ...
Husain F. Hassan, Inas I. Rasheed
doaj +1 more source
Characterization of the adenosine deaminase-adenosine deaminase complexing protein binding reaction. [PDF]
Journal of Biological Chemistry, 1990 Glutaraldehyde-fixed membranes from rabbit kidney cortex were used to characterize binding of monomeric adenosine deaminase to the adenosine deaminase complexing protein. With the use of bovine adenosine deaminase it was shown that enzyme binding is a saturable, high affinity process. The K value for binding of the bovine enzyme was 11 nM.
A D Miczek +3 more
openaire +2 more sources
Purinergic Dysfunction and Electrolyte Imbalance in Newly Diagnosed Bipolar Disorder Patients: A Case-control Study [PDF]
Indian Journal of Medical BiochemistryAim and background: Patients with bipolar disorder experience alternating episodes of mania and depression. Adenosine, a purinergic base, plays a critical role in regulating mood, sleep, activity, appetite, cognition, memory, seizure threshold, social ...
Gayathri Ponnusamy, C Mythili
doaj +1 more source
Biomedicines, 2022 Chronic hypoxia drives vascular dysfunction by various mechanisms, including changes in mitochondrial respiration. Although endothelial cells (ECs) rely predominantly on glycolysis, hypoxia is known to alter oxidative phosphorylation, promote oxidative ...
Barbara Kutryb-Zajac +6 more
doaj +1 more source
Journal of Clinical Immunology, 2018 Deficiency of ADA2 (DADA2) is the first molecularly described monogenic vasculitis syndrome. DADA2 is caused by biallelic hypomorphic mutations in the ADA2 gene that encodes the adenosine deaminase 2 (ADA2) protein.
I. Meyts, I. Aksentijevich
semanticscholar +1 more source
Localization of adenosine deaminase and adenosine deaminase complexing protein in rabbit brain. [PDF]
Journal of Histochemistry & Cytochemistry, 1987 Adenosine deaminase and adenosine deaminase complexing protein have been localized in rabbit brain. Brains fixed in paraformaldehyde or in Clarke's solution were blocked coronally. Blocks from brains fixed in paraformaldehyde were either frozen in liquid nitrogen or embedded in paraffin.
Norman L. Strominger +2 more
openaire +3 more sources