Results 191 to 200 of about 105,286 (352)

Targeting aerobic glycolysis combats tyrosine kinase inhibitor resistance of hepatocellular carcinoma

International Journal of Cancer, Volume 158, Issue 3, Page 475-487, 1 February 2026.
Abstract Hepatocellular carcinoma (HCC) represents the predominant form of primary liver cancer and is frequently identified at a late stage, necessitating systemic therapy. However, resistance to first‐line tyrosine kinase inhibitor therapies, such as sorafenib and lenvatinib, remains a significant clinical challenge.
Longtao Zhao, Junjie Cheng, Yiming Zheng, Jing Wu, Jia Fan, Haixiang Sun, Chao Gao   +6 more
wiley   +1 more source

EVALUATION OF THE HUMAN BLOOD PLATELETS SENSITIVITY TO AN ACTIVATION AGONIST ADENOSINE DIPHOSPHATE BY SCANNING FLOW CYTOMETRY UNDER CONDITIONS OF ANTIPLATELET THERAPY

, 2022
Alena L. Litvinenko, Vyacheslav M. Nekrasov, E. Chetvertak, Valeri P. Maltsev   +3 more
openalex   +2 more sources

In Vitro and Clinical Evaluation of Potential Interactions of Bemnifosbuvir with Drug Transporters

The Journal of Clinical Pharmacology, Volume 66, Issue 2, February 2026.
Abstract Bemnifosbuvir is a novel oral guanosine nucleotide prodrug candidate for the treatment of chronic hepatitis C virus infection. Potential drug–drug interactions (DDIs) of bemnifosbuvir as a substrate or perpetrator with regard to ATP‐binding cassette (ABC) and solute carrier (SLC) transporters were evaluated in vitro and in clinical studies ...
Xiao‐Jian Zhou, Alex Vo, Gaetano Morelli, Maureen Montrond, Shannan Lynch, Keith Pietropaolo, Bruce Belanger, Arantxa Horga, Nancy Agrawal, Janet Hammond   +9 more
wiley   +1 more source

Adenosine diphosphate-ribosylation greatly affects proteins function: a focus on neurodegenerative diseases. [PDF]

Front Aging Neurosci
Huang C, Xiao H, Yang Y, Luo J, Lai Y, Liu S, Mao K, Chen J, Wang L.   +8 more
europepmc   +1 more source

A simple, rapid preparation ofα-[³²p]- labelled adenosine diphosphate [PDF]

, 1977
Iain L. Cartwright, D. W. Hutchinson
openalex   +1 more source

Distinct Metabolomic Alterations Are Associated With Physical Function, Weight Loss, and Muscle Mass in Men With Cancer

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 1, February 2026.
ABSTRACT Background Treatments for cancer cachexia, defined as involuntary weight and muscle mass loss leading to significant functional impairment, remain unavailable partly due to insufficient improvement of clinically meaningful outcomes in current trials.
Lindsey J. Anderson, Lu Xia, Haiming Kerr, Marin Cabrera, Fabien Chu, Jaqueline Rose, Peter C. Wu, Atreya Dash, Sina A. Gharib, Jose M. Garcia   +9 more
wiley   +1 more source

A pan-tumor review of the role of poly(adenosine diphosphate ribose) polymerase inhibitors. [PDF]

CA Cancer J Clin
Hage Chehade C, Gebrael G, Sayegh N, Ozay ZI, Narang A, Crispino T, Golan T, Litton JK, Swami U, Moore KN, Agarwal N.   +10 more
europepmc   +1 more source

Patient cost sharing during poly(adenosine diphosphate-ribose) polymerase inhibitor treatment in ovarian cancer. [PDF]

Am J Obstet Gynecol, 2021
Harrison RF, Fu S, Sun CC, Zhao H, Lu KH, Giordano SH, Meyer LA.   +6 more
europepmc   +1 more source

TEG platelet mapping and impedance aggregometry to predict platelet transfusion during cardiopulmonary bypass in pediatric patients [PDF]

, 2019
Baltagi, Sirine, Barker, Erin E, Gage, Brian F, Gazit, Avihu Z, Saini, Arun, Shea, Susan M, Spinella, Philip C   +6 more
core   +1 more source

Adenosine Diphosphate Glucose Pyrophosphorylase

Journal of Biological Chemistry, 1966
Hara Prasad Ghosh, Jack Preiss
openaire   +1 more source