Results 111 to 120 of about 227,189 (359)
Advanced NanoBiomed Research, EarlyView.Low‐dose radiotherapy has been shown to direct nanoscale coordination polymers (NCPs) to tumors by promoting neutrophil recruitment. This immune‐mediated delivery strategy markedly enhances tumor targeting and the therapeutic efficacy of NCPs carrying combination chemotherapies or innate immune modulators, even under clinically relevant radiation ...
Langston Tillman +4 more
wiley +1 more source
Study of Cyclic Adenosine Monophosphate Microdomains in Cells
, 2005 Cyclic adenosine monophosphate (cAMP) controls the physiological response to many diverse extracellular stimuli. To maintain signal specificity, cAMP-mediated signaling is finely tuned by means of a complex array of proteins that control the spatial and temporal dynamics of the second messenger within the cell.
Mongillo, M +4 more
openaire +3 more sources
Metabolism‐Regulating Nanomedicines for Cancer Therapy
Advanced NanoBiomed Research, EarlyView.This review highlights metabolism‐regulating nanomedicines designed to target glycolytic, lipid, amino acid, and nucleotide pathways in tumors. By incorporating metabolism‐regulating agents into versatile nanocarriers such as liposomes, micelles, dendrimers, and engineered bacteria, these platforms achieve targeted delivery, controlled release ...
Xiao Wu, Shiyi Geng, Jian Yang
wiley +1 more source
Biochemistry and Biophysics ReportsLonely guy (LOG) proteins are phosphoribohydrolases (PRHs) that are key cytokinin (CK)-activating enzymes in plant and non-plant CK-producing organisms.
Megan M. Aoki +5 more
doaj +1 more source
Administration of metformin in clinical medicine; an updated mini-review on current findings [PDF]
Journal of Nephropharmacology, 2018 Metformin is in the biguanide class that has been considered as the treatment for insulin resistance diabetes and polycystic ovarian disease. Many mechanisms have been suggested for it such as inhibition of the mitochondrial respiratory chain and ...
Mahrang Hedaiaty
doaj
The Guanylate Cyclase C-cGMP Signaling Axis Opposes Intestinal Epithelial Injury and Neoplasia. [PDF]
, 2018 Guanylate cyclase C (GUCY2C) is a transmembrane receptor expressed on the luminal aspect of the intestinal epithelium. Its ligands include bacterial heat-stable enterotoxins responsible for traveler\u27s diarrhea, the endogenous peptide hormones ...
Rappaport, Jeffrey A., Waldman, Scott A.
core +2 more sources
0D Fluorescent Nanomaterials: Preparation, Properties, and its Antibacterial Applications
Advanced NanoBiomed Research, EarlyView.This article reviews the synthesis methods and typical properties of representative 0D fluorescent nanomaterials such as carbon dots, quantum dots, and metal nanoclusters, while also exploring their antibacterial applications in various fields including medical and health care, food, agriculture, and industry.
Tianyi Lu +7 more
wiley +1 more source
DNA sensor cGAS-mediated immune recognition
Protein & Cell, 2016 The host takes use of pattern recognition receptors (PRRs) to defend against pathogen invasion or cellular damage. Among microorganism-associated molecular patterns detected by host PRRs, nucleic acids derived from bacteria or viruses are tightly ...
Pengyan Xia +4 more
doaj +1 more source
Molecular, Enzymatic, and Cellular Characterization of Soluble Adenylyl Cyclase From Aquatic Animals. [PDF]
, 2018 The enzyme soluble adenylyl cyclase (sAC) is the most recently identified source of the messenger molecule cyclic adenosine monophosphate. sAC is evolutionarily conserved from cyanobacteria to human, is directly stimulated by [Formula: see text] ions ...
Acin-Perez +58 more
core +2 more sources
The Role of Adenosine Signaling in Headache: A Review
Brain Sciences, 2017 Migraine is the third most prevalent disease on the planet, yet our understanding of its mechanisms and pathophysiology is surprisingly incomplete. Recent studies have built upon decades of evidence that adenosine, a purine nucleoside that can act as a ...
Nathan T. Fried +2 more
doaj +1 more source