Results 221 to 230 of about 95,796 (312)

Activation of G protein‐coupled parathyroid hormone receptors in rat incisor odontoblasts promotes mineralization via cyclic adenosine monophosphate, not Ca2+ signalling: In vitro study

open access: yesInternational Endodontic Journal, EarlyView.
Abstract Aim Parathyroid hormone (PTH) and its Gαs‐coupled receptors, PTH receptor, mediate odontoblast differentiation; however, the detailed intracellular adenylyl cyclase‐mediated signalling pathway mediated by the PTH–PTH receptor axis remains to be elucidated. Therefore, we measured the intracellular levels of cyclic adenosine monophosphate (cAMP)
Natsuki Saito   +4 more
wiley   +1 more source

Role of Staphylococcus aureus Nasal Carriage in Uremic Pruritus and Infection in Hemodialysis Patients

open access: yesInternational Journal of Dermatology, EarlyView.
Schematic representation showing the association between Staphylococcus aureus nasal carriage and increased prevalence and severity of uremic pruritus in hemodialysis patients, along with a potential link to subsequent infection risk. ABSTRACT Background While Staphylococcus aureus (S. aureus) is a well‐recognized concern in hemodialysis (HD) patients,
Mei‐Ju Ko   +8 more
wiley   +1 more source

CD73 Expression by CD4+ T Cells Marks Early Effector Memory T Cells

open access: yesImmunology, EarlyView.
The role of CD73 in the development of naïve CD4+ T cells. Naïve CD4+ T cells, which are negative for CD25, CD44, and positive for CD62L, are depicted based on the expression of CD73. CD73− and CD73+ subpopulations among naïve CD4+ T cells bear distinct characteristics.
Luxia Chen   +5 more
wiley   +1 more source

Canagliflozin protects cardiovascular function in type 2 diabetic coronary artery disease by regulating natriuretic peptide B

open access: yesJournal of Diabetes Investigation, EarlyView.
Canagliflozin regulated the cyclic guanosine monophosphate (cGMP)‐protein kinase 1‐α signaling pathway through the natriuretic peptide B gene, thereby improving cell viability, apoptosis, and reactive oxygen species levels, and ultimately protecting cardiac function in type 2 diabetic patients with coronary artery disease.
Jiarui Zhang   +5 more
wiley   +1 more source

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