Results 311 to 320 of about 165,902 (383)

Effects of pasture consumption and obesity on insulin dysregulation and adiponectin concentrations in UK native‐breed ponies

Equine Veterinary Journal, EarlyView.
Abstract Background Insulin dysregulation (ID) and hypoadiponectinaemia (total [adiponectin] <7.9 μg/mL) are risk factors for laminitis. They are sometimes, but not always, associated with obesity. Objectives To investigate the effects of pasture consumption and obesity on ID and circulating total [adiponectin] in ponies.
Marine A. Barnabé, Jonathan Elliott, Patricia A. Harris, Nicola J. Menzies‐Gow   +3 more
wiley   +1 more source

Lactucopicrin promotes fatty acid β-oxidation and attenuates lipid accumulation through adenosine monophosphate-activated protein kinase activation in free fatty acid-induced human hepatoblastoma cancer cells. [PDF]

Food Sci Nutr
Tan H, Mi N, Tong F, Zhang R, Abudurexiti A, Lei Y, Zhong Y, Yan J, Yang J, Ma X.   +9 more
europepmc   +1 more source

Effects of Lipolytic and Antilipolytic Agents on Cyclic 3',5'-Adenosine Monophosphate in Fat Cells

, 1971
Vincent C. Manganiello, Ferid Murad, Martha Vaughan   +2 more
openalex   +1 more source

Osteochondrosis in horses: An overview of genetic and other factors

Equine Veterinary Journal, EarlyView.
Abstract Osteochondrosis (OC) is a frequent manifestation of developmental orthopaedic disease, and its severe clinical presentation is known as OC dissecans (OCD). OC is defined as a disruption of the endochondral ossification process in the epiphyseal cartilage, and this disease has been reported in different mammalian species, including humans, dogs,
Lola Martinez‐Saez, Pablo J. Marín‐García, M. Lola Llobat   +2 more
wiley   +1 more source

Dissociation and reassociation of the phosphorylated and nonphosphorylated forms of adenosine 3':5' -monophosphate-dependent protein kinase from bovine cardiac muscle.

, 1976
R Rangel-Aldao, O M Rosen
openalex   +1 more source

Hypoxia modulates the purine salvage pathway and decreases red blood cell and supernatant levels of hypoxanthine during refrigerated storage [PDF]

, 2018
Doctor, Allan, et al.,, Rogers, Stephen C   +2 more
core   +1 more source

Harnessing nucleotide metabolism and immunity in cancer: a tumour microenvironment perspective

The FEBS Journal, EarlyView.
This review explores how changes in nucleotide metabolism affect the tumour microenvironment and immune responses in cancer. Here, we discuss the dual role of nucleotide metabolism in promoting cancer cell growth and shaping immune suppression. We highlight how therapies targeting nucleotide pathways can enhance immunotherapy efficacy, offering new ...
Hadil Suleiman, Alexandra Emerson, Peter M. Wilson, Karl A. Mulligan, Robert D. Ladner, Melissa J. LaBonte   +5 more
wiley   +1 more source

The universal role of adaptive transcription in health and disease

The FEBS Journal, EarlyView.
Adaptive transcription via molecules such as CREB, MEF2, SRF, AP1, Nr4a1, and Egr1 constitutes a universal mechanism for directed cell state transitions in health and disease. These molecules are involved in physiological adaptation processes, pathological maladaptations, curative adaptations, and development of resistance to treatment.
Thomas Lissek
wiley   +1 more source

Viability Profiles of Normal and Cancer Bladder Cells With Metformin, Nitrate and Adenosine Monophosphate-Activated Protein Kinase Inhibitor. [PDF]

World J Oncol
Abdelmoaty H, Good S, Phan T.
europepmc   +1 more source

Transfer RNA and small molecule therapeutics for aminoacyl‐tRNA synthetase diseases

The FEBS Journal, EarlyView.
Aminoacyl‐tRNA synthetases catalyze the ligation of a specific amino acid to a cognate tRNA—a reaction that lays the foundations for deciphering the genetic code. Pathogenic alleles in these synthetases can lead to dominant or recessive disorders, for which little or no disease‐specific treatments exist.
Tristan N. Samuels, Fanqi Wu, Maria Mahmood, Wajd A. Abuzaid, Nancy Sun, Angelica Moresco, Victoria M. Siu, Patrick O'Donoghue, Ilka U. Heinemann   +8 more
wiley   +1 more source