Results 31 to 40 of about 189,720 (274)

Copper-transporting P-type adenosine triphosphatase (ATP7A) is associated with platinum-resistance in non-small cell lung cancer (NSCLC)

Journal of Translational Medicine, 2012
Background Copper export protein ATP7A is important for maintaining copper homeostasis. Recent studies have shown that copper transporters are also involved in the transport of platinum.
Li Zhuang-hua, Qiu Miao-zhen, Zeng Zhao-lei, Luo Hui-yan, Wu Wen-jing, Wang Feng, Wang Zhi-qiang, Zhang Dong-sheng, Li Yu-hong, Xu Rui-hua   +9 more
doaj   +1 more source

Sea buckthorn (Hippophae rhamnoides L.) oil exhibits antifungal activity against Aspergillus flavus via disrupting mitochondrial function

Czech Journal of Food Sciences, 2022
The present study sought to examine how sea buckthorn (SBT) oil impacts mitochondrial and overall functionality in Aspergillus flavus. In order to assess the effect of SBT oil, it was used to treat mycelia across a range of concentrations, after which ...
Yanhua Xin, Jie Yang, Sanhu Zhao, Kewen Chen, Yaqin Zhao, Tiedan Zhang, Jianhua Zhang   +6 more
doaj   +1 more source

Mettl3‐Mediated m6A Modification Represents a Novel Therapeutic Target for FSGS

Advanced Science, EarlyView.
This study explores the roles of Mettl3‐induced N6‐methyladenosine (m6A) modifications in Focal segmental glomerulosclerosis (FSGS). The findings reveal that inhibition of Mettl3 results in podocyte injury by modulating the TJP1CDC42 pathway. Moreover, Administration of N6‐methyladenosine attenuates the FSGS phenotype in WT mice induced by Adriamycin ...
Fubin Zhu, Hongzhi Li, Xiang Li, Chunxiu Du, Ting Wang, Xuling Zhou, Xiaobei Xie, Yunxia Shao, Yingzhi Huang, Yanling Hu, Xinxin Guo, Bin Zhu, Shanshan Yu, Xiaoyan Zhang, Binghai Zhao   +14 more
wiley   +1 more source

Supplementary Figure 1 from Inhibition of the Sodium Potassium Adenosine Triphosphatase Pump Sensitizes Cancer Cells to Anoikis and Prevents Distant Tumor Formation [PDF]

, 2023
Craig D. Simpson, Imtiaz A. Mawji, Kika Anyiwe, Moyo A. Williams, Xiaoming Wang, Amudha L. Venugopal, Marcela Gronda, Rose Hurren, Sonia Cheng, Stefano Serra, Reza Beheshti Zavareh, Alessandro Datti, Jeffrey L. Wrana, Shereen Ezzat, Aaron D. Schimmer   +14 more
openalex   +2 more sources

Vacuolar H⁺-ATPase Subunit V0C Regulates Aerobic Glycolysis of Esophageal Cancer Cells via PKM2 Signaling

Cells, 2019
The vacuolar H+-adenosine triphosphatase (ATPase) subunit V0C (ATP6V0C), a proton-conducting, pore-forming subunit of vacuolar ATPase, maintains pH homeostasis and induces organelle acidification.
Sung Wook Son, Gia Cac Chau, Seong-Tae Kim, Sung Hee Um   +3 more
doaj   +1 more source

Cellular senescence triggers intracellular acidification and lysosomal pH alkalinized via ATP6AP2 attenuation in breast cancer cells

Communications Biology, 2023
Several chemotherapeutic drugs induce senescence in cancer cells; however, the mechanisms underlying intracellular pH dysregulation in senescent cells remain unclear. Adenosine triphosphatase H+ transporting accessory protein 2 (ATP6AP2) plays a critical
Wei Li, Kosuke Kawaguchi, Sunao Tanaka, Chenfeng He, Yurina Maeshima, Eiji Suzuki, Masakazu Toi   +6 more
doaj   +1 more source

A Transmembrane Segment Determines the Steady-State Localization of an Ion-Transporting Adenosine Triphosphatase

Journal of Cell Biology, 2000
The H,K-adenosine triphosphatase (ATPase) of gastric parietal cells is targeted to a regulated membrane compartment that fuses with the apical plasma membrane in response to secretagogue stimulation.
L. Dunbar, P. Aronson, M. Caplan
semanticscholar   +1 more source

1‐Methylcyclopropene Containing‐Paper Enhances the Storability of Anxi Persimmon by Regulating Energy Metabolism

Future Postharvest and Food, EarlyView.
1‐Methylcyclopropene (1‐MCP) containing‐paper delayed the color change and maintained higher rate of commercially acceptable fruit in Anxi persimmons during storage were attributed to the increased activities of H+‐ATPase, Ca2+‐ATPase, and Mg2+‐ATPase and higher levels of ATP content and energy charge (EC).
Lingzhen Zeng, Lili Shi, Yuzhao Lin, Yixiong Lin, Hetong Lin, Hui Wang   +5 more
wiley   +1 more source

Evaluation of sexual dimorphism of histochemical activity of phosphatases of the plantar glands of Norway rats (Rattus norvegicus)

Biosystems Diversity, 2019
The activity of acid phosphatase, alkaline phosphatase and adenosine triphosphatase in the eccrine and sebaceous glands of the skin of the soles of the paws of male and female Norway rats was studied by histochemiсal methods.
A. B. Kiladze, N. K. Dzhemukhadze
doaj   +1 more source

Update on Thiamine Triphosphorylated Derivatives and Metabolizing Enzymatic Complexes

Biomolecules, 2021
While the cellular functions of the coenzyme thiamine (vitamin B1) diphosphate (ThDP) are well characterized, the triphosphorylated thiamine derivatives, thiamine triphosphate (ThTP) and adenosine thiamine triphosphate (AThTP), still represent an ...
Lucien Bettendorff
doaj   +1 more source