Results 71 to 80 of about 189,720 (274)

Y6, an Epigallocatechin Gallate Derivative, Reverses ABCG2-Mediated Mitoxantrone Resistance

open access: yesFrontiers in Pharmacology, 2019
Multidrug resistance is reported to be related to the transmembrane transportation of chemotherapeutic drugs by adenosine triphosphate-binding cassette (ABC) transporters.
Rui-Qiang Zhao   +11 more
doaj   +1 more source

Lactylation of Mitochondrial Adenosine Triphosphate Synthase Subunit Alpha Regulates Vascular Remodeling and Progression of Aortic Dissection

open access: yesResearch
Aortic dissection (AD) is a cardiovascular disorder with a high mortality rate. Lysine Lactylation (Kla), a novel posttranslational modification, critically regulates inflammation, tumors, and cardiovascular diseases.
Tao Yu   +10 more
doaj   +1 more source

Assessment of Adenosine Triphosphatase Phospholipid Transporting 8B1 (ATP8B1) Function in Patients With Cholestasis With ATP8B1 Deficiency by Using Peripheral Blood Monocyte-Derived Macrophages. [PDF]

open access: yesHepatol Commun, 2021
Mizutani A   +25 more
europepmc   +1 more source

Possible mechanisms of lack of dentin bridge formation in response to calcium hydroxide in primary teeth

open access: yesDental Hypotheses, 2015
Introduction: The usage of Calcium hydroxide (CaOH2) has wide applications due to the property of osteo-inductive, protective, and antibacterial actions.
G R Ravi, R V Subramanyam
doaj   +1 more source

Breakdown and repair of metabolism in the aging brain

open access: yesFrontiers in Science
Age-related neurodegenerative disorders, including dementia, are a major global health concern. This article describes the first comprehensive, data-driven molecular model of the neuro-glia-vascular system to explore the complex relationships between the
Polina Shichkova   +11 more
doaj   +1 more source

Inhibition of adenosine triphosphatases by gold [PDF]

open access: yesArthritis & Rheumatism, 1980
AbstractInhibition of adenosine triphosphatase (ATPase) by chlorauric acid (Au3+) and gold sodium thiomalate (Au+) was studied in dog brain and kidney and in human kidney enzyme preparations. Au3+ indiscriminately affected ouabain‐sensitive (Na+ + K+‐dependent) ATPase and ouabain‐insensitive (Mg2+‐dependent) ATPase with concentrations for 50 ...
openaire   +2 more sources

Spontaneous spreading depolarizations originate subcortically in a novel mouse model of familial hemiplegic migraine type 2

open access: yesNeurobiology of Disease
The mechanisms of initiation of spreading depolarization (SD) are understudied due to a paucity of disease models with spontaneously occurring events.
Nico A. Jansen   +14 more
doaj   +1 more source

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