ATP11C mutation is responsible for the defect in phosphatidylserine uptake in UPS-1 cells
Journal of Lipid Research, 2015 Type IV P-type ATPases (P4-ATPases) translocate phospholipids from the exoplasmic to the cytoplasmic leaflets of cellular membranes. We and others previously showed that ATP11C, a member of the P4-ATPases, translocates phosphatidylserine (PS) at the ...
Naoto Takada +4 more
doaj +1 more source
Sestrin2 is a leucine sensor for the mTORC1 pathway [PDF]
, 2016 Leucine is a proteogenic amino acid that also regulates many aspects of mammalian physiology, in large part by activating the mTOR complex 1 (mTORC1) protein kinase, a master growth controller.
Cantor, J. R. +6 more
core +1 more source
In Favor of Establishment: Regulation of Chromatid Cohesion in Plants
Frontiers in Plant Science, 2017 In eukaryotic organisms, the correct regulation of sister chromatid cohesion, whereby sister chromatids are paired and held together, is essential for accurate segregation of the sister chromatids and homologous chromosomes into daughter cells during ...
Pablo Bolaños-Villegas +4 more
doaj +1 more source
The Nobel Prize in Chemistry 2004: 'ubiquitous' quality control of life [PDF]
, 2005 The Nobel Prize in Chem. for 2004 is shared by Aaron Ciechanover, Avram Hershko and Irwin Rose, who made fundamental discoveries concerning how cells regulate the breakdown of cellular proteins with extreme specificity.
Karigar, C.S., Siddalinga Murthy, K.R.
core +1 more source
Clathrin coat controls synaptic vesicle acidification by blocking vacuolar ATPase activity
eLife, 2018 Newly-formed synaptic vesicles (SVs) are rapidly acidified by vacuolar adenosine triphosphatases (vATPases), generating a proton electrochemical gradient that drives neurotransmitter loading.
Zohreh Farsi +8 more
doaj +1 more source
Mechanisms of Degranulation in Neutrophils [PDF]
, 2006 Neutrophils are critical inflammatory cells that cause tissue damage in a range of diseases and disorders. Being bone marrow-derived white blood cells, they migrate from the bloodstream to sites of tissue inflammation in response to chemotactic signals ...
Paige Lacy
core +1 more source
mTORC1 Senses Lysosomal Amino Acids Through an Inside-Out Mechanism That Requires the Vacuolar H+-ATPase [PDF]
, 2011 The mTOR complex 1 (mTORC1) protein kinase is a master growth regulator that is stimulated by amino acids. Amino acids activate the Rag guanosine triphosphatases (GTPases), which promote the translocation of mTORC1 to the lysosomal surface, the site of ...
Bar-Peled, Liron +5 more
core +1 more source
Regulation of Mitochondrial Dynamics by Proteolytic Processing and Protein Turnover
Antioxidants, 2018 The mitochondrial network is a dynamic organization within eukaryotic cells that participates in a variety of essential cellular processes, such as adenosine triphosphate (ATP) synthesis, central metabolism, apoptosis and inflammation.
Sumaira Ali, Gavin P. McStay
doaj +1 more source
A splicing-dependent transcriptional checkpoint associated with prespliceosome formation [PDF]
, 2014 There is good evidence for functional interactions between splicing and transcription in eukaryotes, but how and why these processes are coupled remain unknown.
Ahn +62 more
core +1 more source
Adenosine triphosphatase staining of dermatophytes
Acta Dermato-Venereologica, 1971 No abstract ...
W B, Shelley, L, Juhlin
openaire +2 more sources