Results 41 to 50 of about 104,099 (211)

Dissolved Organic Phosphorus Utilization by Phytoplankton Reveals Preferential Degradation of Polyphosphates Over Phosphomonoesters

Frontiers in Marine Science, 2018
The nutritionally available pool of dissolved organic phosphorus (DOP) supports marine primary productivity in a range of ocean ecosystems but remains poorly resolved. Here, the relative lability of model phosphorus (P) compounds representing the major P(
Julia M. Diaz, Alisia Holland, James G. Sanders, Karrie Bulski, Douglas Mollett, Douglas Mollett, Chau-Wen Chou, Dennis Phillips, Yuanzhi Tang, Solange Duhamel   +9 more
doaj   +1 more source

Inhibition of adenosine triphosphatases by gold [PDF]

Arthritis & Rheumatism, 1980
AbstractInhibition of adenosine triphosphatase (ATPase) by chlorauric acid (Au3+) and gold sodium thiomalate (Au+) was studied in dog brain and kidney and in human kidney enzyme preparations. Au3+ indiscriminately affected ouabain‐sensitive (Na+ + K+‐dependent) ATPase and ouabain‐insensitive (Mg2+‐dependent) ATPase with concentrations for 50 ...
openaire   +2 more sources

ATP6V1A deletion leads to impaired clearance of septic cardiac resident macrophages

陆军军医大学学报
Objective To investigate the clearance capacity of cardiac resident macrophages in post-sepsis and its underlying mechanism. Methods A mouse model of sepsis was established using cecum perforation ligation. Thirty male C57BL/6 mice (8 weeks old, weighing
YANG Shunxin, ZHOU Yuanqun, XIANG Xinming   +2 more
doaj   +1 more source

Stimulation of glia reveals modulation of mammalian spinal motor networks by adenosine [PDF]

, 2015
This work was funded by the Wellcome Trust Institutional Strategic Support Fund for University of St. Andrews.Despite considerable evidence that glia can release modulators to influence the excitability of neighbouring neurons, the importance of ...
Miles, Gareth B., David Acton, Acton David, Miles Gareth B., Acton, David, Gareth B Miles   +5 more
core   +2 more sources

Anterior cingulate cortex neuron subtypes differentially regulate seizures

Epilepsia, EarlyView.
Abstract Objective This study aimed to investigate the regulatory roles of distinct neuronal subtypes within the anterior cingulate cortex (ACC) in acute seizures and to identify cell type‐specific mechanisms underlying seizure modulation in this region. Methods Acute seizure models were established in mice via pentylenetetrazol injection.
Ziqian Yan, Ting Tang, Kaishan Wang, Bin Fu, Zesheng Li, Mingshan Liu, Hongyi Huang, Yanfeng Yang, Qiang Zheng, Yangmin Zheng, Yongzhi Shan, Yumin Luo, Guoguang Zhao   +12 more
wiley   +1 more source

Influence of Histamine on Adenosine Triphosphatase

Experimental Biology and Medicine, 1948
In all snake venoms hitherto investigated a powerful ATP-ase (ophio-ATP-ase) has been found, which is activated by magnesium, calcium and cobalt ions and inhibited by zinc ions.1,2 Histamine and pyridoxamine act as inhibitors, epinephrine as activator.The question arose as to whether similar reactions take place in the animal tissues and thus ...
openaire   +2 more sources

Clinical predictors of response to methotrexate in patients with rheumatoid arthritis: A systematic review

Rheumatology &Autoimmunity, EarlyView.
This review integrates clinical, immunological, genetic, and multi‐omic evidence, highlighting dynamic inflammatory and adenosine‐pathway biomarkers and reinforcing treat‐to‐target principles as the most actionable framework for personalized methotrexate therapy.
Joana Ramos Rodrigues, Helena Margarida de Miranda Lemos Romão Donato, Soraia Raquel Loureiro Azevedo, Luís Miguel da Silva Pires, Luís Pedro Bolotinha de Sousa Inês, Manuel Augusto Nunes Vicente Passos Morgado, Ana Filipa de Sousa Pestana Mourão   +6 more
wiley   +1 more source

Retrospective comparison of treatments for equine gastric ulceration syndrome and the influence of inflammatory bowel disease

Equine Veterinary Education, EarlyView.
Summary Background Equine squamous gastric disease (ESGD) and equine glandular gastric disease (EGGD) can be treated with oral omeprazole, combined with sucralfate or an extended‐release intramuscular omeprazole (ERIO). Objectives To evaluate these different treatments for ESGD and EGGD and assess the influence of inflammatory bowel disease (IBD) on ...
L. C. Kranenburg, C. Ludin, D. A. van Doorn, M. M. Sloet van Oldruitenborgh‐Oosterbaan, P. Witt, R. M. A. C. Houben, R. van den Boom   +6 more
wiley   +1 more source

CD36‐mediated lipid rewiring in the metabolic adaptation of tumour ecosystems

The FEBS Journal, EarlyView.
Nutrient deprivation drives a lipid‐centric shift in tumour metabolic symbiosis and signalling network. CD36 functions as a bidirectional bridge, transferring fatty acids from stromal donors (adipocytes, CAFs) to the ecosystem tumour‐ and microenvironment‐dependently.
Anna Sebestyén, Viktória Varga, Fatime Szalai, Risa Miyaura, Nóra Förhécz, Bálint Csikós, Rebeka Gelencsér, Zsófia Gábriel, Timea Komlódi, Katalin Dezső, Ildikó Krencz, Dorottya Moldvai   +11 more
wiley   +1 more source

Membrane transporter genes predict chemoradiotherapy response in patients with cervical cancer [PDF]

Einstein (São Paulo)
Introduction: Cervical cancer is the fourth most common cancer in women worldwide. Resistance to chemoradiotherapy in cervical cancer has been widely associated with membrane transport-related genes, particularly those encoding efflux transport proteins,
Natália Gregório Custódio, Fábio Ribeiro Queiroz, Angelo Borges de Melo Neto, Brenda Martins Cavalcante, Laurence Rodrigues do Amaral, Telma Maria Rossi de Figueiredo Franco, Matheus de Souza Gomes, Vasco Ariston de Carvalho Azevedo, Letícia da Conceição Braga, Paulo Guilherme de Oliveira Salles, Wander de Jesus Jeremias   +10 more
doaj   +1 more source