RNA specificity and regulation of catalysis in the eukaryotic polynucleotide kinase clp1 [PDF]
, 2014 RNA-specific polynucleotide kinases of the Clp1 subfamily are key components of various RNA maturation pathways. However, the structural basis explaining their substrate specificity and the enzymatic mechanism is elusive.
Zeymer, C. +5 more
core +1 more source
Membrane transporter genes predict chemoradiotherapy response in patients with cervical cancer [PDF]
Einstein (São Paulo)Introduction: Cervical cancer is the fourth most common cancer in women worldwide. Resistance to chemoradiotherapy in cervical cancer has been widely associated with membrane transport-related genes, particularly those encoding efflux transport proteins,
Natália Gregório Custódio +10 more
doaj +1 more source
Journal of Fish Diseases, EarlyView.ABSTRACT Formalin‐inactivated vaccines are widely employed as a primary preventive strategy against red sea bream iridoviral disease (RSIVD), which poses a substantial economic threat to the aquaculture of rock bream (Oplegnathus fasciatus). However, conventional quantitative PCR (qPCR) cannot differentiate infectious virions from noninfectious vaccine
Sung‐Bin Moon +8 more
wiley +1 more source
H+-ATPsintetase de cloroplastos (CF0F1): interação enzima/substrato ; efeito de espécies reativas de oxigênio e de nitrogênio em lipossomas [PDF]
, 2001 Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde.
Morfim, Marcos Paulo
core
Influence of Histamine on Adenosine Triphosphatase
Experimental Biology and Medicine, 1948 In all snake venoms hitherto investigated a powerful ATP-ase (ophio-ATP-ase) has been found, which is activated by magnesium, calcium and cobalt ions and inhibited by zinc ions.1,2 Histamine and pyridoxamine act as inhibitors, epinephrine as activator.The question arose as to whether similar reactions take place in the animal tissues and thus ...
openaire +2 more sources
LEAD-ADENOSINE TRIPHOSPHATE COMPLEXES IN ADENOSINE TRIPHOSPHATASE HISTOCHEMISTRY [PDF]
Journal of Histochemistry & Cytochemistry, 1969 Chelation of lead by adenosine triphosphate (ATP) and its consequences for adenosine triphosphatase histochemistry were examined. The formation constant of lead-ATP chelates was found by two methods to be 4.6-4.7 x 10 4 .
openaire +2 more sources
The Journal of Physiology, EarlyView.Abstract figure legend Suboptimal maternal nutrition alters placental and developing blood–brain barrier (BBB) protective function and is associated with increased fetal brain vulnerability. In the placenta, nutritional adversity may reduce the exchange surface area and promote meta‐inflammation, compromising barrier efficiency in a model‐ and context ...
Kristin L. Connor +4 more
wiley +1 more source
The relationship between nerve terminal adenosine triphosphatases and neurotransmitter release:As determined by the use of antidepressant and other CNS-active drugs [PDF]
, 1980 The role of adenosine triphosphatases (ATPases) in neurotransmitter release was studied using nerve terminals (synaptosomes) prepared from rat cerebral cortex as a model.
Wyllie, M. G., Gilbert, John C
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Molecular mechanisms of temperature adaptation in fish myofibrillar adenosine triphosphatases [PDF]
, 1977 Studies have been carried out on the Mg2+ Ca2+-myofibrillar ATPase from the muscles of fish adapted to different environmental temperatures. The thermal stability of the ATPase is strongly correlated with mean habitat temperature. Activities of Antarctic
Walesby, N.J., Johnston, Ian A.
core +1 more source
Discontinuing Long‐Term Denosumab in Treating Fragile Bone: Why, for Whom, and How?
Clinical Pharmacology &Therapeutics, Volume 120, Issue 2, Page 334-344, August 2026.Discontinuation of denosumab (Dmab) may be necessary due to adverse events or an unfavorable long‐term risk–benefit profile. However, accumulating evidence demonstrates pronounced rebound phenomena after withdrawal, most notably a marked increase in multiple vertebral fractures, and, in some reports, elevated mortality.
Ko‐Hsiu Lu +5 more
wiley +1 more source