Results 181 to 190 of about 275,348 (354)

SP1‐Mediated Glycolytic Reprogramming Promotes Tumorigenesis and Progression in Pancreatic Cancer

open access: yesAdvanced Science, EarlyView.
Laser capture microdissection‐based proteomics of pancreatic intraepithelial neoplasia (PanIN) identifies specificity protein 1 (SP1) as a key driver of tumorigenesis and progression in pancreatic cancer through glycolytic remodeling. SP1 enhances aerobic glycolysis by transcriptionally activating 6‐phosphofructo‐2‐kinase/fructose‐2,6‐bisphosphatase ...
Hexing Hang   +21 more
wiley   +1 more source

Thermosensory TRPV Heterotetramers Drive Seasonal Polyphenism: Molecular Basis of CcIav/CcNan‐PKCα‐AKH/AKHR Signaling in Pear Psyllid Morph Transition

open access: yesAdvanced Science, EarlyView.
At 2 5 °C, thermal activation initiates: i) CcIav/CcNan heterotetramer assembly → Ca2⁺ influx; ii) CcPKCα phosphorylation → AKH signaling potentiation; iii) CcAKH1 binding to membrane‐localized CcAKHR → energy mobilization (lipid catabolism/glycogenolysis) and vitellogenin transport via follicular patency; iv) Oocyte maturation → summer‐form nymph ...
Jianying Li   +6 more
wiley   +1 more source

Vortex‐Generated Microdroplets Enable Simple, Rapid, and Low‐Volume Measurement of Condensate Volume and Concentration

open access: yesAdvanced Science, EarlyView.
This work leverages vortex‐generated microdroplets to encapsulate condensates and quantify their volumes and concentrations. Compared to conventional bulk methods, the technique substantially reduces sample volume, cost, and processing time. Its broad utility sheds light on a wide range of applications, particularly those that require high‐throughput ...
Feipeng Chen, Ho Cheung Shum
wiley   +1 more source

On the Dephosphorylation and Deamination of Adenosine Triphosphate by Actomyosin Gel.

open access: bronze, 1954
Adam Deutsch   +3 more
openalex   +1 more source

Mild Photothermal Bimetallic Mesoporous Nanozyme Triggers Immunogenic Cell Death and Immune Contexture Remodeling for Precision Hepatocellular Carcinoma Treatment

open access: yesAdvanced Science, EarlyView.
In this study, a Pt/Co BNzyme with peroxidase/GPx‐like activity is developed, increasing oxidative stress by generating ROS and depleting GSH to induce ICD. The mild PTT effect enhanced its enzymatic activity. The Pt/Co BNzyme remodeled the TME, promoting DC maturation.
Yanbing Huang   +9 more
wiley   +1 more source

A Simple and Rapid Determination of ATP, ADP and AMP Concentrations in Pericarp Tissue of Litchi Fruit by High Performance Liquid Chromatography

open access: yesFood Technology and Biotechnology, 2006
A simple and rapid method using high performance liquid chromatography (HPLC) was developed to determine levels of adenosine triphosphate (ATP), adenosine diphosphate (ADP) and adenosine monophosphate (AMP) in litchi fruit pericarp tissue.
Weibo Jiang   +3 more
doaj  

Home - About - Disclaimer - Privacy