Results 281 to 290 of about 474,757 (353)

Biocompatible Chemistry: A Plug‐and‐Play Toolbox for Chemical Biology Research

ChemBioChem, EarlyView.
The “plug‐and‐play” nature of biocompatible chemistry makes it a powerful toolbox for investigating complicated biological systems and producing drug leads for clinical usages. This review summarizes the commonly used biocompatible reactions and the recent advances of their representative applications in chemical biology research, thus highlighting the
Adam R. Lovato, Zeng Lin, Qingfei Zheng
wiley   +1 more source

Synthesis of a Biologically Important Adenosine Triphosphate Analogue, ApppD

ACS Omega, 2017
Petri A. Turhanen
doaj   +1 more source

Activation of Adenosine Triphosphate-Gated Purinergic 2 Receptor Channels by Transient Receptor Potential Vanilloid Subtype 4 in Cough Hypersensitivity. [PDF]

Biomolecules
Li W, Wang S, Zhang T, Zhu Y, Yu L, Xu X.   +5 more
europepmc   +1 more source

Structure‐Based Rational Design of a Selective Hydrolase Inhibitor of the Severe Acute Respiratory Syndrome Coronavirus‐2 Nsp3 Macrodomain

ChemBioChem, EarlyView.
Structure‐guided design of a sulfamoyl‐modified analog of GS‐441524 yielded a selective, high‐affinity inhibitor of the SARS‐CoV‐2 macrodomain Nsp3b. The compound occupies the phosphate‐binding pocket, forming a stabilizing hydrogen‐bond network that enhances binding affinity (K_D = 0.86 μM).
Robin Krishnathas, Konstantin S. Mineev, Nikolaos K. Fourkiotis, Franck Touret, Christos Sideras‐Bisdekis, Aikaterini C. Tsika, Santosh Lakshmi Gande, Verena Linhard, Sridhar Sreeramulu, Frank Lennartz, Manfred S. Weiss, Bruno Coutard, Georgios A. Spyroulias, Harald Schwalbe   +13 more
wiley   +1 more source

Adenosine triphosphate mediates the pain tolerance effect of manual acupuncture at Zusanli (ST36) in mice. [PDF]

J Tradit Chin Med
Zhongzheng LI, Yadan Z, Weigang M, Yonglong Z, Zhifang XU, Qiang XI, Yanqi LI, Siru Q, Zichen Z, Songtao W, Xue Z, Yangyang L, Yi G, Yongming G.   +13 more
europepmc   +1 more source

Effect of intravenous adenosine-5’-triphosphate (ATP) on cerebral blood flow in awake man

, 1976
Shiro Tominaga, Katsuhiro Watanabe
openalex   +1 more source

Bufalin‐Induced Epithelial‐to‐Mesenchymal Transition in Kidney Epithelial Cells

Cell Biology International, EarlyView.
ABSTRACT The kidney plays a central role in fluid, electrolyte, and blood pressure regulation, processes tightly coupled to Na⁺/K⁺‐ATPase activity. Beyond its canonical transport function, Na⁺/K⁺‐ATPase also acts as a signaling receptor for cardiotonic steroids (CTSs) such as bufalin, which have been implicated in fibrosis and epithelial‐to‐mesenchymal
Gabriela Morais de Oliveira Barros, Kayo M. Bagri, Claudia Mermelstein, Luis Eduardo M. Quintas   +3 more
wiley   +1 more source

Prodrug-inspired adenosine triphosphate-activatable celastrol-Fe(III) chelate for cancer therapy. [PDF]

Sci Adv
Li H, Li Y, Zhang L, Wang N, Lu D, Tang D, Lv Y, Zhang J, Yan H, Gong H, Zhang M, Nie K, Hou Y, Yu Y, Xiao H, Liu C.   +15 more
europepmc   +1 more source

Study of genetic polymorphisms of adenosine triphosphate-binding cassette B1 (ABCB1) gene in Iraqi nephrotic syndrome patients on prednisolone therapy [PDF]

Rawan Azad Mohammed, Ahmed Salih Sahib, Qahtan Mohammed Ali   +2 more
openalex   +1 more source

The Aging Gut–Brain Axis: Effects of Dietary Polyphenols and Metal Exposure

Chronic Diseases and Translational Medicine, EarlyView.
The influence of gut microbiota on brain health ABSTRACT Diet provides essential metals, which are required for the growth, development, and well‐functioning of the body. Nonetheless, some natural and human activities add toxic heavy metals to the diet, consequently introducing them to our bodies, resulting in several disorders and death. The intestine,
Luqi Cao, Saurabh Kumar Jha, Neha Gupta, Xiang Chen, Renuka Soni, Luoxi Yuan, Rashi Srivastava, Zhe‐Sheng Chen   +7 more
wiley   +1 more source