Results 311 to 320 of about 253,092 (356)

Gut microbiota and risk of heart failure in European population—A comprehensive Mendelian randomization study

open access: yesESC Heart Failure, EarlyView.
Abstract Aims Gut dysbiosis is proven to be involved in the pathogenesis and progression of heart failure (HF). Hindering the detrimental effects of gut‐heart axis is an emerging trend. Our goal is to investigate the causal relationship between gut microbiota and HF, with the aim of facilitating future exploration of microbiome‐targeted approaches to ...
Liyan Huang   +8 more
wiley   +1 more source

Impact of glucose and pyruvate on adenosine triphosphate production and sperm motility in goats. [PDF]

open access: yesAnim Biosci
Setiawan R   +7 more
europepmc   +1 more source

Mitochondrial targets in ischaemic heart disease and heart failure, and their potential for a more efficient clinical translation. A scientific statement of the ESC Working Group on Cellular Biology of the Heart and the ESC Working Group on Myocardial Function

open access: yesEuropean Journal of Heart Failure, EarlyView.
Improving clinical translation of mitoprotective therapies. 31P MRI, phosphorus‐31 magnetic resonance imaging; hiPSC‐CM, human‐induced pluripotent stem cell‐derived cardiomyocyte; IHD, ischaemic heart disease. Abstract Acute myocardial infarction (MI) remains a major cause of death and disability worldwide.
Melanie Paillard   +29 more
wiley   +1 more source

Heart failure and obesity: Translational approaches and therapeutic perspectives. A scientific statement of the Heart Failure Association of the ESC

open access: yesEuropean Journal of Heart Failure, EarlyView.
Abstract Obesity and heart failure (HF) represent two growing pandemics. In the general population, obesity affects one in eight adults and is linked with an increased risk for HF. Obesity is even more common in patients with HF, where it complicates the diagnosis of HF and is linked with worse symptoms and impaired exercise capacity. Over the past few
Gianluigi Savarese   +28 more
wiley   +1 more source

Effect of Substituents on the Tautomerism of Pyridone Nucleoside Analogs

open access: yesEuropean Journal of Organic Chemistry, Volume 28, Issue 14, April 7, 2025.
Experimental and quantum‐chemical work shows that the predominant tautomer of 6‐fluoropyridones is the lactim, not the lactam form. This makes them analogs of cytosine, not uracil or thymine in the context of incorporation opposite complementary bases of genetic sequences. Abstract Nucleobase analogs are important tools in medicine and chemical biology,
Leon Stark   +7 more
wiley   +1 more source

Recent Advances in Palladium‐Catalyzed Phosphonation of Aryl Halides, Sulfonates and Related Derivatives

open access: yesEuropean Journal of Organic Chemistry, EarlyView.
This review provides an in‐depth exploration of recent progress in palladium‐catalyzed phosphonation, focusing on the use of aryl halides, sulfonates and related derivatives as key substrates. It discusses innovations in catalytic systems, reaction conditions, and substrate versatility while addressing limitations such as low reactivity of certain ...
YiYi Yang, On Ying Yuen, Chau Ming So
wiley   +1 more source

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