Results 151 to 160 of about 281,343 (303)
From HBV to MASLD Cirrhosis: Mechanistic Insights and Therapeutic Strategies
Portal Hypertension &Cirrhosis, EarlyView.This review examines the epidemiological shift from hepatitis B virus (HBV) to metabolic dysfunction‐associated steatotic liver disease (MASLD) as the leading cause of cirrhosis globally. It highlights the distinct pathogenic mechanisms between HBV and MASLD cirrhosis and discusses evolving diagnostic tools and therapeutic strategies tailored to the ...
Hanqi Yu +5 more
wiley +1 more source
CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 572-582, March 2025.ABSTRACT The antitumor efficacy of an intratumoral injection of a genetically engineered oncolytic vaccinia virus carrying human IL‐7 and murine IL‐12 genes (hIL‐7/mIL‐12‐VV) was demonstrated in CT26.WT‐bearing mice. In the CT26.WT‐bearing mouse model, the efficacy of the combination of hIL‐7/mIL‐12‐VV plus the anti‐programmed cell death protein (PD)‐1
Akihiro Yamada +13 more
wiley +1 more source
VIEW, EarlyView.PHF1 is a known epigenetic regulator involved in transcriptional silencing in cancer. In this study, we identified PHF1 as an oncogene that promotes PDAC progression and demonstrated that its inhibition induces ferroptosis. Mechanistically, PHF1 physically interacts with the FBL/NOP56/NOP58 snoRNP complex to enhance the IRES‐dependent translation of ...
Yujiao Xie +9 more
wiley +1 more source
Use of polymerase chain reaction for detection of adenovirus in children with or without wheezing
The Turkish Journal of Pediatrics, 2005 Eighty percent of asthma attacks in children are accompanied by an upper respiratory tract viral infection. Adenovirus is one of the major viral causes of childhood bronchiolitis.
Cansin Saçkesen +4 more
doaj
Epac1 Alleviates Senescence in Auditory Hair Cells via the Ferroptosis
World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.ABSTRACT Objectives The aim of this study was to investigate the changes in Epac1 and ferroptosis‐related proteins in aged mice and the House Ear Institute‐Organ of Corti 1 (HEI‐OC1) cells, with the goal of elucidating their potential role in age‐related hearing loss. Methods The expression of Epac1 in the cochlea of C57BL/6J mice was examined by using
Wen‐Jun An +7 more
wiley +1 more source
Acute Kidney Injury, Fever, and Dark Urine in a Kidney Transplant Recipient. [PDF]
Kidney360Rosenstiel PE, Goyal A.
europepmc +1 more source
Gene therapy for B-cell lymphoma in a SCID mouse model using an immunoglobulin-regulated diphtheria toxin gene delivered by a novel adenovirus-polylysine conjugate [PDF]
, 1994 Cook, Deborah R. +8 more
core +1 more source
Reactive Infectious Mucocutaneous Eruption (RIME): An Australian Case Series
Australasian Journal of Dermatology, EarlyView.ABSTRACT Whilst Reactive Infectious Mucocutaneous Eruption (RIME) displays a low mortality rate, the condition results in significant morbidity and resource allocation, including prolonged hospital admission. As such, early diagnosis and optimisation of treatment is imperative.
Hamish Moore +2 more
wiley +1 more source
Adenovirus Disease Following Pediatric Liver Transplantation: 10-Year Experience From a Large Pediatric Transplant Program. [PDF]
Pediatr TransplantBanc-Husu AM +8 more
europepmc +1 more source