Results 171 to 180 of about 186,768 (239)

Role of BK Virus CTLs in the Treatment of BK Virus–Associated Nephropathy in Kidney‐Transplant and Hematopoietic Cell Transplant Recipients

Transplant Infectious Disease, EarlyView.
Third‐party, BK virus‐specific cytotoxic T lymphocytes (CTLs) were safe and effective in reducing viremia in kidney and stem cell transplant recipients with BK virus nephropathy. However, they did not improve kidney function. Earlier administration may be more beneficial before nephropathy and irreversible damage occur.
Amanda Olson, Ye Ethan Li, Rafet Basar, Pinaki Banerjee, Indresh Kaur, Glorette Abueg, Melihate Sylejmani, Nadima Uprety, Rejeena Shrestha, Francia Reyes Silva, Valda Page, Richard E. Champlin, Dimitrios P. Kontoyiannis, Roy F. Chemaly, Elizabeth J. Shpall, Linda Moore, Osama A. Gaber, Katayoun Rezvani, Ala Abudayyeh   +18 more
wiley   +1 more source

An Ocular Manifestation of a Systemic Disease With Encephalitozoon Pogonae in a Juvenile Central Bearded Dragon (Pogona vitticeps)

Veterinary Ophthalmology, EarlyView.
ABSTRACT Objective Encephalitozoon pogonae, a recently identified microsporidian species, has been associated with systemic infections in Central bearded dragons (Pogona vitticeps) manifesting as granulomatous inflammation and vasculitis. Despite the species similarity to Encephalitozoon cuniculi, which causes ocular, neurologic, and renal pathology in
Vanessa Raphtis, Megan Roeder, Augusto Jimenez‐Romero, Danielle Meritet, Kelli Chan, Sarah Ozawa, Michala de Linde Henriksen   +6 more
wiley   +1 more source

Acute hepatitis in a biological male patient secondary to suspected disseminated gonococcal infection in the absence of Fitz-Hugh-Curtis syndrome: a case report. [PDF]

J Med Case Rep
Snedegar RL, Williamson J, Epperly M.
europepmc   +1 more source

One day of environment‐induced heat stress causes injury to the murine kidney

Experimental Physiology, EarlyView.
Abstract Environment‐induced heat stress (EIHS) results from sustained body temperature elevation owing to prolonged exposure to heat and humidity. We hypothesized that EIHS would cause kidney injury and cellular dysfunction. To test this hypothesis, female C57 mice were exposed to EIHS (n = 14; 37.6°C, 42.0% relative humidity) or thermoneutral (TN ...
Melissa Roths, Alyona Michael, Zachary J. Schlader, Joshua T. Selsby   +3 more
wiley   +1 more source

Early-life infection dynamics and genomic diversity of adenoviruses in a wild primate (<i>Theropithecus gelada</i>). [PDF]

Microb Genom
Saroff MJ, Haile AA, Baniel A, Kraberger S, Regney M, Harrach B, Kaján GL, Lu A, Beehner JC, Bergman TJ, Snyder-Mackler N, Varsani A, Schneider-Crease IA.   +12 more
europepmc   +1 more source

The skeletal muscle–adipose creatine metabolic axis: A novel paradigm for lipid metabolism reprogramming and obesity management

Experimental Physiology, EarlyView.
Abstract The global prevalence of obesity and related metabolic disorders has spurred interdisciplinary research to develop new intervention strategies. Current research is increasingly focusing on the exercise‐induced browning of white adipose tissue and the mechanisms by which it improves energy metabolism.
Yuhui Su, Na Liu, Yang Liu, Yiqun Sun, Yike Jiao   +4 more
wiley   +1 more source

SAMHD1 drives immunosuppression in non-small cell lung cancer by promoting macrophage infiltration and restricting oncolytic adenovirus replication. [PDF]

J Immunother Cancer
Hu S, Xu J, Wang Z, Zhang Y, Zhao C, Liu Y, Luo F, Cheng P, Wang J, Zhao J.   +9 more
europepmc   +1 more source

Mitochondrial oxidative stress, calcium and dynamics in cardiac ischaemia‐reperfusion injury

The Journal of Physiology, EarlyView.
Abstract figure legend Heart attack causes ischaemia–reperfusion injury in cardiomyocytes. Mitochondria generate reactive oxygen species (ROS), leading to oxidative stress. High levels of mitochondrial calcium (Ca2+) activate the mitochondrial permeability transition pore (mPTP), and excess ROS levels can lower the Ca2+ required to activate the mPTP ...
Emily Rozich, Ulas Ozkurede, Shanmugasundaram Pakkiriswami, Ryan Gemilere, Samira M. Azarin, Julia C. Liu   +5 more
wiley   +1 more source

Epidemiological characteristics and genomic analysis of respiratory adenovirus in Lanzhou City from 2023 to 2025. [PDF]

Front Cell Infect Microbiol
Wang B, Liang S, Wei H, Wang M, Zhang X, Dong M, Zhang H.   +6 more
europepmc   +1 more source

Hyperglycaemia‐induced reactive oxygen species production in cardiac ventricular myocytes differs among mammals

The Journal of Physiology, EarlyView.
Abstract figure legend In rat and human adult ventricular myocytes, acute hyperglyceaemia (Glucose) causes increased glucose uptake (via GLUT) leading to O‐GlcNAcylation of CaMKII at Ser280, such that CaMKII activates NADPH oxidase 2 (NOX2) to increase cytosolic reactive oxygen species (ROS). That perturbs the ROS to Antioxidant (AntiOx) balance.
Shan Lu, Maria J. Baier, Risto‐Pekka Polonen, Zhandi Liao, Jody L. Martin, Kenneth S. Ginsburg, Julian Mustroph, Donald M. Bers   +7 more
wiley   +1 more source