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Adenovirus [PDF]

open access: yesPediatrics In Review, 2010
Of the 53 different human adenovirus (HAdV) serotypes belonging to species A-G, a significant number are associated with acute respiratory, gastrointestinal and ocular infections. Replication-defective HAdV-5-based vectors also continue to play a significant role in gene transfer trials and in vaccine delivery efforts in the clinic.
Jason G, Smith   +3 more
openaire   +4 more sources

Determining new functions of Adenovirus VA-RNAI and its use in cancer therapy [PDF]

open access: yes, 2009
PhDVirus-Associated RNA I (VA-RNAI; VAI) of adenovirus is a nontranslated RNA molecule known to interact with several dsRNA-binding molecules in host cells.
Binny, Christopher Jonathan
core   +4 more sources

Combined CD8+ and CD4+ adenovirus hexon-specific T cells associated with viral clearance after stem cell transplantation as treatment for adenovirus infection

open access: yesHaematologica, 2010
Background Human adenovirus can cause morbidity and mortality in immunocompromised patients after allogeneic stem cell transplantation. Reconstitution of adenovirus-specific CD4+ T cells has been reported to be associated with sustained protection from ...
Maarten L. Zandvliet   +12 more
doaj   +1 more source

Analysis of mortality risk factors in children with severe adenovirus pneumonia: A single-center retrospective study

open access: yesPediatrics and Neonatology, 2023
Background: Human adenovirus (HAdV) is one of the most common viruses causing respiratory infections among young children. Most adenovirus infections are mild and self-limited; however, these infections may occasionally cause severe pneumonia and even ...
Xue-Hua Xu   +6 more
doaj   +1 more source

Brain tumors induced in rats by human adenovirus type 12 [PDF]

open access: yes, 1974
Oncogenesis of human adenovirus type 12 in the brain of rats was examined. Newborn rats of Sprague-Dawley and Donryu strains were injected intracranially with human adenovirus type 12. The incidence of intracranial tumors was 91% (30/33) in
Ogawa, Katsuo   +5 more
core   +1 more source

Adenovirus and its interaction with host cell proteins [PDF]

open access: yes, 2007
The E1B55k gene in adenovirus type 5 was studied by generating recombinant viruses in which the E1B55k gene was N-terminally tagged with either a cyan fluorescent protein (CFP) tag or a tandem affinity purification (TAP) tag.
Carr, Sharon
core   +2 more sources

Enteric adenovirus associated with acute gastroenteritis among hospitalized and healthy childern under five - years of age in Basrah, Iraq [PDF]

open access: yesThe Medical Journal of Basrah University, 2019
Background: Enteric Adenovirus are second to rotavirus as viral cause of acute gastroenteritis in infants and young children. Aims of the study: This study aimed on determination of the incidence of enteric adenovirus-associated gastroenteritis in ...
Hazim Thewainy, Hassanf Hasony
doaj   +1 more source

Adenovirus

open access: yesMicrobiology Spectrum, 2016
ABSTRACTAdenoviruses are a highly prevalent infection that can cause a range of clinical syndromes in immunocompromised patients, ranging from localized disease of the respiratory tract, gastrointestinal tract, or urinary tract to disseminated disease.
Michael G, Ison, Randall T, Hayden
openaire   +2 more sources

Assessment and development of adenovirus type 11 for cancer therapy [PDF]

open access: yes, 2010
PhDThe efficacy of oncolytic virotherapy is influenced by the interactions between the tumour, virus and host immunity. The first generation of oncolytic adenoviruses, based on serotype 5 (Ad5), has achieved limited success in clinical trials.
Wong, Han Hsi
core   +4 more sources

Retrospective study of adenovirus in autopsied pulmonary tissue of pediatric fatal pneumonia in South China

open access: yesBMC Infectious Diseases, 2008
Background Adenovirus are the important pathogen of pediatric severe pneumonia. The aim of this study is to analyze the infection, subtype and distribution of adenovirus in autopsied pulmonary tissue of fatal pneumonia in infants and children, and the ...
Gong Si-Tang   +9 more
doaj   +1 more source

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