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Adenovirus [PDF]

open access: yesPediatrics In Review, 2010
Of the 53 different human adenovirus (HAdV) serotypes belonging to species A-G, a significant number are associated with acute respiratory, gastrointestinal and ocular infections. Replication-defective HAdV-5-based vectors also continue to play a significant role in gene transfer trials and in vaccine delivery efforts in the clinic.
Jason G, Smith   +3 more
openaire   +4 more sources

Combined CD8+ and CD4+ adenovirus hexon-specific T cells associated with viral clearance after stem cell transplantation as treatment for adenovirus infection

open access: yesHaematologica, 2010
Background Human adenovirus can cause morbidity and mortality in immunocompromised patients after allogeneic stem cell transplantation. Reconstitution of adenovirus-specific CD4+ T cells has been reported to be associated with sustained protection from ...
Maarten L. Zandvliet   +12 more
doaj   +1 more source

Adenovirus

open access: yesMicrobiology Spectrum, 2016
ABSTRACTAdenoviruses are a highly prevalent infection that can cause a range of clinical syndromes in immunocompromised patients, ranging from localized disease of the respiratory tract, gastrointestinal tract, or urinary tract to disseminated disease.
Michael G, Ison, Randall T, Hayden
openaire   +2 more sources

Molecular and epidemiological characteristics of adenovirus isolated in patients with acute diarrhea in Ningxia, 2015 – 2020

open access: yesZhongguo gonggong weisheng, 2022
ObjectiveTo examine infection characteristics and genetic evolution of adenovirus isolated in patients with diarrhea in Ningxia Hui Autonomous Region (Ningxia) for providing evidence to the prevention and control of human adenovirus infection ...
An-qi SHI, Kai-xin WEI, Min CAO
doaj   +1 more source

Enteric adenovirus associated with acute gastroenteritis among hospitalized and healthy childern under five - years of age in Basrah, Iraq [PDF]

open access: yesThe Medical Journal of Basrah University, 2019
Background: Enteric Adenovirus are second to rotavirus as viral cause of acute gastroenteritis in infants and young children. Aims of the study: This study aimed on determination of the incidence of enteric adenovirus-associated gastroenteritis in ...
Hazim Thewainy, Hassanf Hasony
doaj   +1 more source

Retrospective study of adenovirus in autopsied pulmonary tissue of pediatric fatal pneumonia in South China

open access: yesBMC Infectious Diseases, 2008
Background Adenovirus are the important pathogen of pediatric severe pneumonia. The aim of this study is to analyze the infection, subtype and distribution of adenovirus in autopsied pulmonary tissue of fatal pneumonia in infants and children, and the ...
Gong Si-Tang   +9 more
doaj   +1 more source

AAV production in stable packaging cells requires expression of adenovirus 22/33K protein to allow episomal amplification of integrated rep/cap genes

open access: yesScientific Reports, 2023
Efficient manufacture of recombinant adeno-associated virus (rAAV) vectors for gene therapy remains challenging. Packaging cell lines containing stable integration of the AAV rep/cap genes have been explored, however rAAV production needs to be induced ...
Weiheng Su   +2 more
doaj   +1 more source

Adenovirus and miRNAs

open access: yesBiochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, 2011
Adenovirus infection has a tremendous impact on the cellular silencing machinery. Adenoviruses express high amounts of non-coding virus associated (VA) RNAs able to saturate key factors of the RNA interference (RNAi) processing pathway, such as Exportin 5 and Dicer. Furthermore, a proportion of VA RNAs is cleaved by Dicer into viral microRNAs (mivaRNAs)
Carnero, Elena   +2 more
openaire   +2 more sources

Examen de adenovirus con métodos moleculares y patológicos en casos de pneumonía ovina

open access: yesRevista Mvz Cordoba, 2022
Objetivo. Revelar adenovirus (AdV) que causan pneumonía en ovejas y examinar cambios patológicos en los ganglios linfáticos pulmonares y mediastínicos de muestras positivas para adenovirus infectadas de forma natural. Material y métodos.
Muhammet Bahaeddin Dörtbudak   +3 more
doaj   +1 more source

Adenovirus serotype 7 associated with a severe lower respiratory tract disease outbreak in infants in Shaanxi Province, China

open access: yesVirology Journal, 2011
Background Pneumonia caused by adenovirus infection is usually severe especially with adenovirus serotype 7 commonly associated with lower respiratory tract disease outbreaks.
Xu Wenbo   +3 more
doaj   +1 more source

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