Results 11 to 20 of about 291,962 (341)
Cytokine Responses to Adenovirus and Adenovirus Vectors
Viruses, 2022 The expression of cytokines and chemokines in response to adenovirus infection is tightly regulated by the innate immune system. Cytokine-mediated toxicity and cytokine storm are known clinical phenomena observed following naturally disseminated ...
Svetlana Atasheva +1 more
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Adenovirus Biology, Recombinant Adenovirus, and Adenovirus Usage in Gene Therapy [PDF]
Viruses, 2021 Gene therapy is currently in the public spotlight. Several gene therapy products, including oncolytic virus (OV), which predominantly replicates in and kills cancer cells, and COVID-19 vaccines have recently been commercialized. Recombinant adenoviruses,
Maki Watanabe +3 more
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Adenovirus Core Proteins: Structure and Function
Viruses, 2021 Adenoviruses have served as a model for investigating viral-cell interactions and discovering different cellular processes, such as RNA splicing and DNA replication.
Shermila Kulanayake, Suresh K. Tikoo
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Altering the Ad5 packaging domain affects the maturation of the Ad particles. [PDF]
PLoS ONE, 2011 We have previously described a new family of mutant adenoviruses carrying different combinations of attB/attP sequences from bacteriophage PhiC31 flanking the Ad5 packaging domain.
Raul Alba +5 more
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Cellular Physiology and Biochemistry, 2017 Background/Aims: While recombinant adenoviruses are among the most widely-used gene delivery vectors and usually propagated in HEK-293 cells, generating recombinant adenoviruses remains time-consuming and labor-intense.
Qiang Wei +25 more
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Pediatrics In Review, 2010 Of the 53 different human adenovirus (HAdV) serotypes belonging to species A-G, a significant number are associated with acute respiratory, gastrointestinal and ocular infections. Replication-defective HAdV-5-based vectors also continue to play a significant role in gene transfer trials and in vaccine delivery efforts in the clinic.
Jason G, Smith +3 more
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Capturing and concentrating adenovirus using magnetic anionic nanobeads
International Journal of Nanomedicine, 2016 Akikazu Sakudo,1 Koichi Baba,2 Kazuyoshi Ikuta1,31Department of Virology, Research Institute for Microbial Diseases, Osaka University, Yamadaoka, Suita, Osaka, Japan; 2Baba Pediatric Clinic, Kadoma, Osaka, Japan; 3Kanonji Institute, The Research ...
Sakudo A, Baba K, Ikuta K
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Frontiers in Pediatrics, 2021 Objectives: To identify the differences of clinical characteristics and outcomes of severe pneumonia in children under 5 years old with and without adenovirus infection.Methods: A retrospective cohort study was conducted in three pediatric hospitals in ...
Lingling Zheng +8 more
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Human adenovirus infections in pediatric population - An update on clinico–pathologic correlation
Biomedical Journal, 2021 Human adenoviruses can cause infections at any age but most commonly in pediatric population, especially in young children and infants. By the time of 10 years old, most children have had at least one episode of adenovirus infection.
W. Shieh
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A Case Series of Children with Acute Hepatitis and Human Adenovirus Infection
New England Journal of Medicine, 2022 BACKGROUND Human adenoviruses typically cause self-limited respiratory, gastrointestinal, and conjunctival infections in healthy children. In late 2021 and early 2022, several previously healthy children were identified with acute hepatitis and human ...
L. H. G. Sanchez +29 more
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