Results 41 to 50 of about 281,343 (303)

Structural analysis of the adenovirus type 2 E3/19K protein using mutagenesis and a panel of conformation-sensitive monoclonal antibodies [PDF]

, 2008
The E3/19K protein of human adenovirus type 2 (Ad2) was the first viral protein shown to interfere with antigen presentation. This 25 kDa transmembrane glycoprotein binds to major histocompatibility complex (MHC) class I molecules in the endoplasmic ...
Ahmed, Altschul, Andersson, Beatrice Menz, Beier, Bennett, Bruder, Bryson, Burgert, Burgert, Burgert, Burgert, Burgert, Cole, Cox, Deryckere, Edgar, Elsing, Feuerbach, Flomenberg, Flomenberg, Fox, Gabathuler, Gewurz, Ginsberg, Hans-Gerhard Burgert, Hermiston, Hilgendorf, Jackson, Jackson, Jefferies, Katja Koebernick, Kornfeld, Krogh, Kurowski, Köhler, Körner, Lichtenstein, Liu, Liu, Lodoen, Mans, Martina Sester, McNees, McSharry, Nilsson, Persson, Pääbo, Pääbo, Pääbo, Ralf Schmid, Rawle, Rost, Rost, Rost, Sester, Sester, Tanaka, The_UniProt_Consortium, von Herrath, Windheim, Wold, Wold   +62 more
core   +1 more source

The Revolving Door of Adenovirus Cell Entry: Not All Pathways Are Equal

Pharmaceutics, 2021
Adenoviruses represent exceptional candidates for wide-ranging therapeutic applications, from vectors for gene therapy to oncolytics for cancer treatments.
Davor Nestić, Ksenija Božinović, Isabela Pehar, Rebecca Wallace, Alan L. Parker, Dragomira Majhen   +5 more
doaj   +1 more source

Identification of Gastroenteric Viruses by Electron Microscopy Using Higher Order Spectral Features [PDF]

, 2005
Background: Many paediatric illnesses are caused by viral agents, for example, acute gastroenteritis. Electron microscopy can provide images of viral particles and can be used to identify the agents.
Chandran, Vinod, Ong, Chien
core   +2 more sources

Comparative study of adenoviruses with monoclonal antibodies Estudo comparativo de diferentes tipos de adenovirus através de anticorpos monoclonais

Revista do Instituto de Medicina Tropical de São Paulo, 1992
The obtainment of monoclonal antibodies for adenovirus species 4(Ad4) is described.The specificities of selected monoclonal antibodies were determined by means of viral neutralization test in cell culture, immunofluorescence and Enzyme-Linked ...
Terezinha Maria de Paiva, Sueko Takimoto, María Akíko Ishida, María Candida Oliveira de Souza, Tuneo Ishimaru, Jorge Neumann, Jorge Kalil   +6 more
doaj   +1 more source

Acute Respiratory Distress Syndrome Caused by Human Adenovirus in Adults: A Prospective Observational Study in Guangdong, China

Frontiers in Medicine, 2022
BackgroundViral causes of acute respiratory distress syndrome (ARDS) are mostly limited to influenza. However, adenovirus has been emerging as a cause of ARDS with a high mortality rate and described in adults are rare.MethodsWe conducted a prospective ...
Zhan Wu, Rong Zhang, Dongdong Liu, Xuesong Liu, Jierong Zhang, Zhihui Zhang, Sibei Chen, Weiqun He, Yimin Li, Yonghao Xu, Xiaoqing Liu   +10 more
doaj   +1 more source

Adenovirus-mediated gene transfer to liver grafts: An improved method to maximize infectivity [PDF]

, 1998
Background. Adenoviral gene therapy in liver transplantation has many potential applications, but current vector delivery methods to grafts lack efficiency and require high titers. In this study, we attempted to improve gene delivery efficacy using three
Chia, SH, Fung, JJ, Geller, DA, Kibbe, MR, Murase, N, Starzl, TE, Watkins, SC   +6 more
core   +1 more source

Adenovirus-mediated hPNPase(old-35) gene transfer as a therapeutic strategy for neuroblastoma [PDF]

, 2009
Current treatment options for neuroblastoma fail to eradicate the disease in the majority of high-risk patients, clearly mandating development of innovative therapeutic strategies. Gene therapy represents a promising approach for reversing the neoplastic
Ardelt, Arnold, Beck, Benito, Brodeur, Chan, Cinatl, Cinatl, D'Alessio, Hellemans, Holmes, Jasty, Kotchetkov, Lebedeva, Lebedeva, Leszczyniecka, Leszczyniecka, Maris, McConville, Michaelis, Pattyn, Pattyn, Ross, Sarkar, Sarkar, Sarkar, Sarkar, Sarkar, Sarkar, Su, Tweddle, Van Maerken, Vandesompele, Vandesompele, Vasandani, Vasandani, Youle, Young   +37 more
core   +2 more sources

Adenovirus infections [PDF]

Postgraduate Medical Journal, 1973
Summary Ninety-three adenoviruses were found in the MRC/PHLS survey of patients in general practice and eighty-eight in those admitted to hospital, types 1, 2, 3, 5 and 7 being the most frequent ones isolated. The adenoviruses accounted for 11% and 12% of all viruses and were present in 2% and 4% of patients examined in these surveys ...
openaire   +2 more sources

TNF receptor–related factor 3 inactivation promotes the development of intrahepatic cholangiocarcinoma through NF‐κB‐inducing kinase–mediated hepatocyte transdifferentiation

Hepatology, EarlyView., 2022
Abstract Background and Aims Intrahepatic cholangiocarcinoma (ICC) is a deadly but poorly understood disease, and its treatment options are very limited. The aim of this study was to identify the molecular drivers of ICC and search for therapeutic targets.
Yuto Shiode, Takahiro Kodama, Satoshi Shigeno, Kazuhiro Murai, Satoshi Tanaka, Justin Y. Newberg, Jumpei Kondo, Shogo Kobayashi, Ryoko Yamada, Hayato Hikita, Ryotaro Sakamori, Hiroshi Suemizu, Tomohide Tatsumi, Hidetoshi Eguchi, Nancy A. Jenkins, Neal G. Copeland, Tetsuo Takehara   +16 more
wiley   +1 more source

Identification of Inhibitors and Drug Targets for Human Adenovirus Infections

Viruses, 2022
Adenoviruses can cause infections in people of all ages at all seasons of the year. Adenovirus infections cause mild to severe illnesses. Children, immunocompromised patients, or those with existing respiratory or cardiac disease are at higher risk ...
Minli Liu, Lefang Jiang, Weihua Cao, Jianguo Wu, Xulin Chen   +4 more
doaj   +1 more source