Results 21 to 30 of about 163,837 (259)

Case report: a fatal case of disseminated adenovirus infection in a non-transplant adult haematology patient

BMC Infectious Diseases, 2018
Background We report a fatal case of disseminated adenovirus infection in a non-transplant haematology adult patient with chronic lymphocytic leukaemia who had completed combination chemoimmunotherapy a few months before developing respiratory symptoms ...
Michael Joffe, Simon D. Wagner, Julian W. Tang   +2 more
doaj   +1 more source

Gene Delivery by Subconjunctival Injection of Adenovirus in Rats: A Study of Local Distribution, Transgene Duration and Safety. [PDF]

PLoS ONE, 2015
Subconjunctival injection is a minimally invasive route for gene delivery to ocular tissues, but has traditionally been limited to use in the cornea. The accurate ocular distribution of virus has not, however, been previously investigated.
Guei-Sheung Liu, Jiang-Hui Wang, Jia Hui Lee, Pei-Jhen Tsai, Han-En Tsai, Shwu-Jiuan Sheu, Hsiu-Chen Lin, Gregory J Dusting, Ming-Hong Tai, Youn-Shen Bee   +9 more
doaj   +1 more source

The Revolving Door of Adenovirus Cell Entry: Not All Pathways Are Equal

Pharmaceutics, 2021
Adenoviruses represent exceptional candidates for wide-ranging therapeutic applications, from vectors for gene therapy to oncolytics for cancer treatments.
Davor Nestić, Ksenija Božinović, Isabela Pehar, Rebecca Wallace, Alan L. Parker, Dragomira Majhen   +5 more
doaj   +1 more source

Bir Devlet Hastanesine Akut Gastroenterit ile Başvuran Hastalarda Rotavirüs ve Enterik Adenovirüs Enfeksiyonu Sıklığı

Sakarya Tıp Dergisi, 2019
ÖZET Amaç: Rotavirüs ve enterik adenovirüsler, çocukluk çağında gastroenteritlere bağlı hastaneye yatışların çoğunluğundan sorumludur. Rotavirüs ve enterik adenovirüs gastroenteritlerinin bölgemizdeki epidemiyolojisini araştırmak için hastanemize ...
Gürkan Muratdağı, Özlem Kirişci
doaj   +1 more source

Adenoviruses associated with acute diarrhea in children in Beijing, China. [PDF]

PLoS ONE, 2014
Adenoviruses have been recognized as important causal pathogens of community-acquired diarrhea (CAD) among children, but their role in hospital-acquired diarrhea (HAD) is not well-understood.
Liying Liu, Yuan Qian, You Zhang, Jie Deng, Liping Jia, Huijin Dong   +5 more
doaj   +1 more source

Acute Respiratory Distress Syndrome Caused by Human Adenovirus in Adults: A Prospective Observational Study in Guangdong, China

Frontiers in Medicine, 2022
BackgroundViral causes of acute respiratory distress syndrome (ARDS) are mostly limited to influenza. However, adenovirus has been emerging as a cause of ARDS with a high mortality rate and described in adults are rare.MethodsWe conducted a prospective ...
Zhan Wu, Rong Zhang, Dongdong Liu, Xuesong Liu, Jierong Zhang, Zhihui Zhang, Sibei Chen, Weiqun He, Yimin Li, Yonghao Xu, Xiaoqing Liu   +10 more
doaj   +1 more source

TNF receptor–related factor 3 inactivation promotes the development of intrahepatic cholangiocarcinoma through NF‐κB‐inducing kinase–mediated hepatocyte transdifferentiation

Hepatology, EarlyView., 2022
Abstract Background and Aims Intrahepatic cholangiocarcinoma (ICC) is a deadly but poorly understood disease, and its treatment options are very limited. The aim of this study was to identify the molecular drivers of ICC and search for therapeutic targets.
Yuto Shiode, Takahiro Kodama, Satoshi Shigeno, Kazuhiro Murai, Satoshi Tanaka, Justin Y. Newberg, Jumpei Kondo, Shogo Kobayashi, Ryoko Yamada, Hayato Hikita, Ryotaro Sakamori, Hiroshi Suemizu, Tomohide Tatsumi, Hidetoshi Eguchi, Nancy A. Jenkins, Neal G. Copeland, Tetsuo Takehara   +16 more
wiley   +1 more source

Comparative study of adenoviruses with monoclonal antibodies Estudo comparativo de diferentes tipos de adenovirus através de anticorpos monoclonais

Revista do Instituto de Medicina Tropical de São Paulo, 1992
The obtainment of monoclonal antibodies for adenovirus species 4(Ad4) is described.The specificities of selected monoclonal antibodies were determined by means of viral neutralization test in cell culture, immunofluorescence and Enzyme-Linked ...
Terezinha Maria de Paiva, Sueko Takimoto, María Akíko Ishida, María Candida Oliveira de Souza, Tuneo Ishimaru, Jorge Neumann, Jorge Kalil   +6 more
doaj   +1 more source

Apolipoprotein F is reduced in humans with steatosis and controls plasma triglyceride‐rich lipoprotein metabolism

Hepatology, EarlyView., 2022
Hepatic APOF transcript levels correlate inversely with plasma TG and hepatic steatosis in humans. ApoF expression in mice promotes VLDL‐TG production and lipoprotein remnant clearance in mice. Abstract Background NAFLD affects nearly 25% of the global population. Cardiovascular disease (CVD) is the most common cause of death among patients with NAFLD,
Audrey Deprince, Nathalie Hennuyer, Sander Kooijman, Amanda C. M. Pronk, Eric Baugé, Viktor Lienard, An Verrijken, Eveline Dirinck, Luisa Vonghia, Eloïse Woitrain, Niels J. Kloosterhuis, Eléonore Marez, Pauline Jacquemain, Justina C. Wolters, Fanny Lalloyer, Delphine Eberlé, Sandrine Quemener, Emmanuelle Vallez, Anne Tailleux, Mostafa Kouach, Jean‐Francois Goossens, Violeta Raverdy, Bruno Derudas, Jan Albert Kuivenhoven, Mikaël Croyal, Bart van de Sluis, Sven Francque, François Pattou, Patrick C. N. Rensen, Bart Staels, Joel T. Haas   +30 more
wiley   +1 more source

Loss of hepatic SMLR1 causes hepatosteatosis and protects against atherosclerosis due to decreased hepatic VLDL secretion

Hepatology, EarlyView., 2022
The role of SMLR1 in lipid metabolism (high fat + cholesterol diet in mice) Abstract Background and Aims The assembly and secretion of VLDL from the liver, a pathway that affects hepatic and plasma lipids, remains incompletely understood. We set out to identify players in the VLDL biogenesis pathway by identifying genes that are co‐expressed with the ...
Willemien van Zwol, Antoine Rimbert, Justina C. Wolters, Marieke Smit, Vincent W. Bloks, Niels J. Kloosterhuis, Nicolette C. A. Huijkman, Mirjam H. Koster, Umesh Tharehalli, Simon M. de Neck, Colin Bournez, Marceline M. Fuh, Jeroen Kuipers, Sujith Rajan, Alain de Bruin, Henry N. Ginsberg, Gerard J. P. van Westen, M. Mahmood Hussain, Ludger Scheja, Joerg Heeren, Philip Zimmerman, Bart van de Sluis, Jan Albert Kuivenhoven   +22 more
wiley   +1 more source