Results 21 to 30 of about 193,080 (304)

Adenovirus and miRNAs

Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, 2011
Adenovirus infection has a tremendous impact on the cellular silencing machinery. Adenoviruses express high amounts of non-coding virus associated (VA) RNAs able to saturate key factors of the RNA interference (RNAi) processing pathway, such as Exportin 5 and Dicer. Furthermore, a proportion of VA RNAs is cleaved by Dicer into viral microRNAs (mivaRNAs)
Carnero, Elena, Sutherland, James D., Fortes, Puri   +2 more
openaire   +2 more sources

Adenovirus serotype 7 associated with a severe lower respiratory tract disease outbreak in infants in Shaanxi Province, China

Virology Journal, 2011
Background Pneumonia caused by adenovirus infection is usually severe especially with adenovirus serotype 7 commonly associated with lower respiratory tract disease outbreaks.
Xu Wenbo, Wang Li, Tan Xiaojuan, Tang Liuying   +3 more
doaj   +1 more source

Gene Delivery by Subconjunctival Injection of Adenovirus in Rats: A Study of Local Distribution, Transgene Duration and Safety. [PDF]

PLoS ONE, 2015
Subconjunctival injection is a minimally invasive route for gene delivery to ocular tissues, but has traditionally been limited to use in the cornea. The accurate ocular distribution of virus has not, however, been previously investigated.
Guei-Sheung Liu, Jiang-Hui Wang, Jia Hui Lee, Pei-Jhen Tsai, Han-En Tsai, Shwu-Jiuan Sheu, Hsiu-Chen Lin, Gregory J Dusting, Ming-Hong Tai, Youn-Shen Bee   +9 more
doaj   +1 more source

CD40 ligand induced cytotoxicity in carcinoma cells is enhanced by inhibition of metalloproteinase cleavage and delivery via a conditionally-replicating adenovirus [PDF]

, 2010
Background CD40 and its ligand (CD40L) play a critical role in co-ordinating immune responses. CD40 is also expressed in lymphoid malignancies and a number of carcinomas. In carcinoma cells the physiological outcome of CD40 ligation depends on the level
Young Lawrence S, Elmetwali, Taha, Mcneish, I., Searle Peter F, Young, Lawrence, Searle, PF, Palmer Daniel H, McNeish, I, Young, Lawrence S., Palmer, D.H., McNeish, Iain, Peter F Searle, Lawrence S Young, Elmetwali, T., Searle, P.F., Elmetwali Taha, Iain McNeish, Young, LS, McNeish Iain, Palmer, Daniel H., Palmer, DH, Searle, Peter F., Daniel H Palmer, Young, L.S., Taha Elmetwali, Palmer, Daniel, Searle, Peter, Elmetwali, T   +27 more
core   +1 more source

Case report: a fatal case of disseminated adenovirus infection in a non-transplant adult haematology patient

BMC Infectious Diseases, 2018
Background We report a fatal case of disseminated adenovirus infection in a non-transplant haematology adult patient with chronic lymphocytic leukaemia who had completed combination chemoimmunotherapy a few months before developing respiratory symptoms ...
Michael Joffe, Simon D. Wagner, Julian W. Tang   +2 more
doaj   +1 more source

The Revolving Door of Adenovirus Cell Entry: Not All Pathways Are Equal

Pharmaceutics, 2021
Adenoviruses represent exceptional candidates for wide-ranging therapeutic applications, from vectors for gene therapy to oncolytics for cancer treatments.
Davor Nestić, Ksenija Božinović, Isabela Pehar, Rebecca Wallace, Alan L. Parker, Dragomira Majhen   +5 more
doaj   +1 more source

Bir Devlet Hastanesine Akut Gastroenterit ile Başvuran Hastalarda Rotavirüs ve Enterik Adenovirüs Enfeksiyonu Sıklığı

Sakarya Tıp Dergisi, 2019
ÖZET Amaç: Rotavirüs ve enterik adenovirüsler, çocukluk çağında gastroenteritlere bağlı hastaneye yatışların çoğunluğundan sorumludur. Rotavirüs ve enterik adenovirüs gastroenteritlerinin bölgemizdeki epidemiyolojisini araştırmak için hastanemize ...
Gürkan Muratdağı, Özlem Kirişci
doaj   +1 more source

Adenoviruses associated with acute diarrhea in children in Beijing, China. [PDF]

PLoS ONE, 2014
Adenoviruses have been recognized as important causal pathogens of community-acquired diarrhea (CAD) among children, but their role in hospital-acquired diarrhea (HAD) is not well-understood.
Liying Liu, Yuan Qian, You Zhang, Jie Deng, Liping Jia, Huijin Dong   +5 more
doaj   +1 more source

Comparative study of adenoviruses with monoclonal antibodies Estudo comparativo de diferentes tipos de adenovirus através de anticorpos monoclonais

Revista do Instituto de Medicina Tropical de São Paulo, 1992
The obtainment of monoclonal antibodies for adenovirus species 4(Ad4) is described.The specificities of selected monoclonal antibodies were determined by means of viral neutralization test in cell culture, immunofluorescence and Enzyme-Linked ...
Terezinha Maria de Paiva, Sueko Takimoto, María Akíko Ishida, María Candida Oliveira de Souza, Tuneo Ishimaru, Jorge Neumann, Jorge Kalil   +6 more
doaj   +1 more source

The structural basis for the integrity of adenovirus Ad3 dodecahedron [PDF]

, 2012
During the viral life cycle adenoviruses produce excess capsid proteins. Human adenovirus serotype 3 (Ad3) synthesizes predominantly an excess of free pentons, the complexes of pentameric penton base and trimeric fiber proteins, which are responsible for
Fender, Pascal, Monika Zochowska (134637), Jean-Pierre Andrieu, Ewa Szolajska (134629), Stephen Cusack (134664), Burmeister, Wim P, Pascal Fender (132764), Szolajska, Ewa, Pascal Fender, Nerlo, Barbara, Burmeister, Wim P., Igor Andreev, Wim P. Burmeister (134634), Wim P Burmeister, Guy Schoehn, Jadwiga Chroboczek (134668), Andreev, Igor, Naskalska, Antonina, Stephen Cusack, Chroboczek, Jadwiga, Barbara Nerlo (134643), Ewa Szolajska, Chloe Zubieta (134662), Barbara Nerlo, Igor Andreev (134649), Andrieu, Jean-Pierre, Jadwiga Chroboczek, Chloe Zubieta, Monika Zochowska, Zochowska, Monika, Cusack, Stephen, Jean-Pierre Andrieu (134655), Schoehn, Guy, Antonina Naskalska, Guy Schoehn (27525), Zubieta, Chloe, Antonina Naskalska (134660)   +36 more
core   +1 more source