Results 21 to 30 of about 210,480 (291)

Adenovirus and miRNAs

Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, 2011
Adenovirus infection has a tremendous impact on the cellular silencing machinery. Adenoviruses express high amounts of non-coding virus associated (VA) RNAs able to saturate key factors of the RNA interference (RNAi) processing pathway, such as Exportin 5 and Dicer. Furthermore, a proportion of VA RNAs is cleaved by Dicer into viral microRNAs (mivaRNAs)
Carnero, Elena, Sutherland, James D., Fortes, Puri   +2 more
openaire   +2 more sources

Effect of immunization with fetal cells on adenovirus-12 oncogenesis [PDF]

, 1974
The effect of immunization with hamster fetal cells on the tumor induction by adnovirus type 12 was studied by in vivo and in vitro. The immunization with lO-day old fetal cells showed a recognizable inhibition on the tumor induction by adenovirus type ...
Abe, Shinji
core   +1 more source

AAV production in stable packaging cells requires expression of adenovirus 22/33K protein to allow episomal amplification of integrated rep/cap genes

Scientific Reports, 2023
Efficient manufacture of recombinant adeno-associated virus (rAAV) vectors for gene therapy remains challenging. Packaging cell lines containing stable integration of the AAV rep/cap genes have been explored, however rAAV production needs to be induced ...
Weiheng Su, Leonard W. Seymour, Ryan Cawood   +2 more
doaj   +1 more source

Examen de adenovirus con métodos moleculares y patológicos en casos de pneumonía ovina

Revista Mvz Cordoba, 2022
Objetivo. Revelar adenovirus (AdV) que causan pneumonía en ovejas y examinar cambios patológicos en los ganglios linfáticos pulmonares y mediastínicos de muestras positivas para adenovirus infectadas de forma natural. Material y métodos.
Muhammet Bahaeddin Dörtbudak, Yavuz Selim Sağlam, Serkan Yıldırım, Mehmet Özkan Timurkan   +3 more
doaj   +1 more source

Requirements for receptor engagement during infection by adenovirus complexed with blood coagulation factor X [PDF]

, 2010
Human adenoviruses from multiple species bind to coagulation factor X (FX), yet the importance of this interaction in adenovirus dissemination is unknown.
Angela C Bradshaw, Duffy, Margaret R., Andrew H. Baker, Lynda Coughlan, Coughlan Lynda, Baker Andrew H., van Rooijen, Nico, van Rooijen, N., Nicklin, Stuart A., Margaret R Duffy, Parker, A.L., Kahari, V.M., Alan L Parker, Kähäri Veli-Matti, Stuart A Nicklin, Nico van Rooijen, Andrew H Baker, Coughlan, L., Nicklin Stuart A., Coughlan, Lynda, Kahari, Veli-Matti, Duffy, M.R., Parker Alan L., Bradshaw Angela C., Parker, Alan L., Duffy Margaret R., Bradshaw, Angela C., Bradshaw, A.C., Rooijen, N. van, Veli-Matti Kähäri, Angela C. Bradshaw, Alan L. Parker, Margaret R. Duffy, Stuart A. Nicklin, Baker, Andrew H., Baker, A.H., Nicklin, S.A., van Rooijen Nico   +37 more
core   +3 more sources

Adenovirus serotype 7 associated with a severe lower respiratory tract disease outbreak in infants in Shaanxi Province, China

Virology Journal, 2011
Background Pneumonia caused by adenovirus infection is usually severe especially with adenovirus serotype 7 commonly associated with lower respiratory tract disease outbreaks.
Xu Wenbo, Wang Li, Tan Xiaojuan, Tang Liuying   +3 more
doaj   +1 more source

The human adenovirus 5 L4 promoter is activated by cellular stress response protein p53 [PDF]

, 2013
During adenovirus infection, the emphasis of gene expression switches from early genes to late genes in a highly regulated manner. Two gene products, L4-22K and L4-33K, contribute to this switch by activating the Major Late Transcription Unit (MLTU) and ...
Leppard, Keith, Wright, Jordan
core   +1 more source

Case report: a fatal case of disseminated adenovirus infection in a non-transplant adult haematology patient

BMC Infectious Diseases, 2018
Background We report a fatal case of disseminated adenovirus infection in a non-transplant haematology adult patient with chronic lymphocytic leukaemia who had completed combination chemoimmunotherapy a few months before developing respiratory symptoms ...
Michael Joffe, Simon D. Wagner, Julian W. Tang   +2 more
doaj   +1 more source

Gene Delivery by Subconjunctival Injection of Adenovirus in Rats: A Study of Local Distribution, Transgene Duration and Safety. [PDF]

PLoS ONE, 2015
Subconjunctival injection is a minimally invasive route for gene delivery to ocular tissues, but has traditionally been limited to use in the cornea. The accurate ocular distribution of virus has not, however, been previously investigated.
Guei-Sheung Liu, Jiang-Hui Wang, Jia Hui Lee, Pei-Jhen Tsai, Han-En Tsai, Shwu-Jiuan Sheu, Hsiu-Chen Lin, Gregory J Dusting, Ming-Hong Tai, Youn-Shen Bee   +9 more
doaj   +1 more source

CD40 ligand induced cytotoxicity in carcinoma cells is enhanced by inhibition of metalloproteinase cleavage and delivery via a conditionally-replicating adenovirus [PDF]

, 2010
Background CD40 and its ligand (CD40L) play a critical role in co-ordinating immune responses. CD40 is also expressed in lymphoid malignancies and a number of carcinomas. In carcinoma cells the physiological outcome of CD40 ligation depends on the level
Young Lawrence S, Elmetwali, Taha, Mcneish, I., Searle Peter F, Young, Lawrence, Searle, PF, Palmer Daniel H, McNeish, I, Young, Lawrence S., Palmer, D.H., McNeish, Iain, Peter F Searle, Lawrence S Young, Elmetwali, T., Searle, P.F., Elmetwali Taha, Iain McNeish, Young, LS, McNeish Iain, Palmer, Daniel H., Palmer, DH, Searle, Peter F., Daniel H Palmer, Young, L.S., Taha Elmetwali, Palmer, Daniel, Searle, Peter, Elmetwali, T   +27 more
core   +1 more source