Inhibition of adenovirus serotype 14 infection by octadecyloxyethyl esters of (S)-[(3-hydroxy-2-phosphonomethoxy)propyl]- nucleosides in vitro. [PDF]
On September 22, 2008, a physician on Prince of Wales Island, Alaska, notified the Alaska Department of Health and Social Services (ADHSS) of an unusually high number of adult patients with recently diagnosed pneumonia (n = 10), including three persons ...
Barnard, Dale L +8 more
core
Epidemiology and potential preventative measures for viral infections in children with malignancy and those undergoing hematopoietic cell transplantation. [PDF]
In pediatric patients with malignancy and those receiving hematopoietic stem cell transplants, bacterial and fungal infections have been the focus of fever and neutropenia episodes for decades.
Alexander, Sarah +5 more
core +1 more source
Effect of Adenovirus Infection on Expression of Human Histone Genes [PDF]
The influence of adenovirus type 2 infection of HeLa cells upon expression of human histone genes was examined as a function of the period of infection. Histone RNA synthesis was assayed after run-off transcription in nuclei isolated from mock-infected cells and after various periods of adenovirus infection.
Flint, S. J. +4 more
openaire +4 more sources
Origin of Thymidine Kinase in Adenovirus-Infected Human Cell Lines [PDF]
Human adenovirus type 5 enhances the thymidine kinase activity of KB cells but does not induce the enzyme in kinase-deficient HeLa (BU25) cells. Vaccinia induces thymidine kinase activity in both KB and HeLa (BU25) cells. Human adenovirus types 2, 4, 7, and 12 also fail to induce the enzyme in HeLa (BU25) cells.
S, Kit, K, Nakajima, D R, Dubbs
openaire +2 more sources
STAT2 Knockout Syrian Hamsters Support Enhanced Replication and Pathogenicity of Human Adenovirus, Revealing an Important Role of Type I Interferon Response in Viral Control. [PDF]
Human adenoviruses have been studied extensively in cell culture and have been a model for studies in molecular, cellular, and medical biology. However, much less is known about adenovirus replication and pathogenesis in vivo in a permissive host because
Karoly Toth +8 more
doaj +1 more source
Development of novel adenoviral vectors to overcome challenges observed with HAdV-5 based constructs [PDF]
Recombinant vectors based on human adenovirus serotype 5 (HAdV-5) have been extensively studied in pre-clinical models and clinical trials over the last two decades.
Julio Alonso-Padilla +215 more
core +4 more sources
Fatal adenoviral necrotizing bronchiolitis case in a post-cardiac surgery intensive care unit
We report a case of a 67 year-old-male patient admitted to the intensive care unit in the postcoronary bypass surgery period who presented cardiogenic shock, acute renal failure and three episodes of sepsis, the latter with pulmonary distress at the 30th
Jussara Bianchi Castelli, M.D., PhD +4 more
doaj +1 more source
Introduction: The role of bacteria in the pathogenesis of periodontitis, pericoronitis, and periapical infections has been well-established. However, the variation in the severity and prognosis of these lesions could suggest a potential role of other ...
Wael Khalil +7 more
doaj +1 more source
Viral hijacking of cellular metabolism. [PDF]
This review discusses the current state of the viral metabolism field and gaps in knowledge that will be important for future studies to investigate.
Ch'ng, James +2 more
core
Molecular epidemiology of human adenovirus infections in Denmark, 2011–2016 [PDF]
Human adenoviruses (HAdVs) can cause respiratory tract infections, conjunctivitis, diarrhoea and outbreaks have been reported. However, little is known about the disease burden and the molecular epidemiology of HAdV.To retrospectively perform a molecular characterization of HAdV positive samples received at Statens Serum Institut during the period 2011-
Barnadas, Céline +3 more
openaire +3 more sources

