Results 121 to 130 of about 236,653 (360)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Identification and functional characterisation of a novel dopamine beta hydroxylase gene variant associated with ADHD

, 2015
Dysregulation in neurotransmitter signalling has been implicated in the aetiology of ADHD. Polymorphisms of the gene encoding dopamine beta hydroxylase (DBH), a key player in catecholamine signalling, have been shown to be associated with increased risk ...
Tong, Janette, Matthews, Natasha, Vance, Alasdair, Heussler, H, Cummins, Tarrant, Kent, L, Cummins, Tarrant D. R., Tarrant D.R. Cummins (567322), Cummins, TDR, Hawi, Z, McKinley, LA, Hawi, Ziarih, Matthews, N, Michael Gill (195307), Alasdair Vance (402134), Ziarih Hawi (402129), Bellgrove, MA, Tong, J, Vance, A, Johnson, Beth, Kent, Lindsey, Helen Heussler (833687), Mark A. Bellgrove (197726), Gill, Michael, Janette Tong (189221), Natasha Matthews (402130), Lindsey Kent (402135), Heussler, Helen, McKinley, Leigh-Anne, Beth Johnson (833686), Belgrove, Mark, Leigh-Anne McKinley (833685), Bellgrove, Mark A., Johnson, B, Gill, M   +34 more
core   +1 more source

ADHD in a women during (peri)menopause: missed diagnoses and cardiac complaints

European Psychiatry
Introduction (Abstract for the accepted case-based workshop by the NDAL section at EPA) Women with ADHD are underdiagnosed in mental health care, and although ADHD starts in early childhood, the symptoms and impairment of women with ADHD may only be ...
J. S. Kooij
doaj   +1 more source

The familial co-aggregation of ASD and ADHD: a register-based cohort study

Molecular Psychiatry, 2017
Autism spectrum disorders (ASD) and attention-deficit/hyperactivity disorder (ADHD) frequently co-occur. The presence of a genetic link between ASD and ADHD symptoms is supported by twin studies, but the genetic overlap between clinically ascertained ASD
L. Ghirardi, Isabell Brikell, R. Kuja-Halkola, C. Freitag, B. Franke, P. Asherson, P. Lichtenstein, Henrik Larsson, Henrik Larsson   +8 more
semanticscholar   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Prevalence of ADHD among the Students Residing in Dormitory of Ardabil University of Medical Sciences [PDF]

Background & Objective: Attention Deficit-Hyperactivity Disorder (ADHD) is a heredity and psychological disorder that often continues to adulthood and causes great number of emotional, social, educational and occupational problem for college students ...
مولوی, پرویز, صادقی موحد, فریبا, صمدزاده, مهدی, عسکری مقدم, راحله, شهباززادگان, بیتا   +4 more
core  

Increased performance uncertainty in children with ADHD? - Elevated post-imperative negative variation (PINV) over the ventrolateral prefrontal cortex

, 2011
Background: We aimed to investigate the influences of attention deficit/hyperactivity disorder (ADHD) on response evaluation, as reflected by the postimperative negative variation (PINV), a slow event-related potential.
Werner, Janina, Resch, Franz, Weisbrod Matthias, Stephan Bender, Rößner, Veit, Matthias Weisbrod, Veit Roessner, Werner Janina, Bender Stephan, Roessner, Veit, Franz Resch, Roessner Veit, Bender, Stephan, Resch Franz, Weisbrod, Matthias, Janina Werner   +15 more
core   +1 more source

Persistence, Remission and Emergence of ADHD in Young Adulthood: Results from a Longitudinal, Prospective Population-Based Cohort

JAMA psychiatry, 2016
Importance ADHD is now recognized to occur in adulthood and is associated with a range of negative outcomes. However, less is known about the prospective course of ADHD into adulthood, the risk factors for its persistence past childhood, and the ...
J. Agnew-Blais, G. Polanczyk, A. Danese, Jasmin Wertz, T. Moffitt, L. Arseneault   +5 more
semanticscholar   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

ADHD IN ADULTS: COMORBODITY WITH BIPOLAR DISORDER AND SUBSTANCE ABUSE

, 2011
ADHD is characterized by a continuous history of hyperactivity, forgetfulness, distractibility, impulsiveness and/or inattention, starting from the early childhood and at a more severe extent than whatever may be usual in peers.
CERAUDO, GIUSEPPE
core