Results 141 to 150 of about 236,653 (360)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Attention Deficit Hyperactivity Disorder (ADHD) in Ophthalmologists: Opportunities and Challenges
Ophthalmology and TherapyAttention deficit hyperactivity disorder (ADHD) is a prevalent neurodevelopmental condition. As an ophthalmologist, having ADHD presents both unique opportunities and considerable challenges, with eye institutions such as the Royal College of ...
Antonia Peilober-Richardson +5 more
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Pharmacological interventions in ADHD
, 2022 ADHD therapy is a multimodal treatment approach that also advocates for a systematic adaptive technique that incorporates several therapy modules based on the patient's and family's needs and circumstances.
Asaly, Majd
core
Systematic review on prevalence of ADHD, possible ADHD or ADHD symptoms in medical students
Frontiers in PsychiatryIntroduction Attention-Deficit/Hyperactivity Disorder (ADHD) is a persistent neurodevelopmental disorder that often continues into adulthood, with a global adult prevalence of approximately 3.1%. Among medical students, the condition may be particularly underdiagnosed and undertreated, despite the intense ...
Lee, Nicholas Yew Wen +1 more
openaire +3 more sources
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
, 2011 The broad aim of this study was to gain a clear picture of how mothers of children with ADHD experience stress, how their stress levels compare to those of mothers of children without ADHD, and which factors predict the extent to which they are ...
Cheesman, Jessica
core
ADHD-s gyermeket nevelő szülők jólléte
, 2023 Az ADHD (figyelemhiányos hiperaktivitás zavar) az egyik leggyakoribb gyermekkorban jelentkező neuropszichológiai megbetegedés. Mivel egyre több családot érint, és számos vitát szít, az ADHD évtizedek óta aktívan kutatott téma.
Sipőcz, Enikő
core