Results 131 to 140 of about 236,653 (360)

The Neuro Bureau ADHD-200 Preprocessed Repository

open access: yesbioRxiv, 2016
In 2011, the “ADHD-200 Global Competition” was held with the aim of identifying biomarkers of attention-deficit/hyperactivity disorder from resting-state functional magnetic resonance imaging (rs-fMRI) and structural MRI (s-MRI) data collected on 973 ...
Lune P Bellec   +5 more
semanticscholar   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

KirstenHilger/ADHD-Modularity ADHD-Modularity

open access: yes, 2019
Analysis Code for Hilger & Fiebach (2018): ADHD Symptoms are Associated with the Modular Structure of Intrinsic Brain Networks in a Representative Sample of Healthy Adults, doi: https://doi.org/10.1101/505891, https://www.biorxiv.org/content/10.1101 ...
Kirsten Hilger
core   +1 more source

Timing of Stimulant Treatment for ADHD and Effect on Academic Progress

open access: yesPediatric Neurology Briefs, 2012
Investigators at University of Iceland, Reykjavik, and other centers in Iceland and in USA studied the probability of academic decline (drop of >5.0 percentile points) in ADHD children according to drug exposure and timing of treatment start between ...
J Gordon Millichap
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

ADHD napjaink problémája

open access: yes, 2021
Az ADHD kialakulásának lehetséges okai, tünetei már csecsemő kortól.Nagyon fontos az ADHD jeleinek korai észlelése kórképének és tüneteinek széles körű ismerete a lehetséges kezelése.
Kovács-Sarkady, Szilvia
core  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Social Adjustment among Taiwanese Children with Symptoms of Adhd, Odd, and Adhd Comorbid with Odd

open access: yes, 2012
This study examined social problems at school and relationships with peers, siblings, mothers, and fathers among children with ADHD only n = 41 , ODD only n = 14, ADHD + ODD n = 47, and normal controls n = 204 from a school- based sample of 2,463 first ...
Tseng, Wan-Ling; Kawabata, Yoshito; Gau, Susan Shur-Fen   +1 more
core   +1 more source

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