Practitioner review: pathways to care for ADHD - a systematic review of barriers and facilitators [PDF]
Background. Attention-Deficit/Hyperactivity Disorder (ADHD) is a common neurodevelopmental disorder starting in childhood that may persist into adulthood.
Chakrabarti, I+9 more
core +2 more sources
Buspirone monotherapy (0.5 mg/kg daily for 6 weeks) was evaluated in 12 children (10 boys, 2 girls), aged 6 to 12 years, with ADHD at the Maudsley Hospital, London, UK.
openaire +4 more sources
Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation
The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt+8 more
wiley +1 more source
The Role of Neurocognitive Tests in the Assessment of Adult Attention-Deficit/Hyperactivity Disorder [PDF]
Despite widespread recognition that attention-deficit/hyperactivity disorder (ADHD) is a lifelong neurodevelopmental disorder, optimal methods of diagnosis among adults remain elusive.
Hoelzle, James B.+2 more
core +1 more source
The effects of stimulants on eating patterns in children and adolescents with Attention Deficit Hyperactivity Disorder [PDF]
Objectives. This study aims to evaluate the effects of methylphenidate (MPH) on eating patterns and body mass index (BMI) in children with attention deficit/hyperactivity disorder (ADHD).
Akay, Aynur Pekcanlar, Turan, Serkan
core +4 more sources
Purification tags markedly affect self‐aggregation of CPEB3
Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito+6 more
wiley +1 more source
Circulating histones as clinical biomarkers in critically ill conditions
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez+17 more
wiley +1 more source
A multicenter, randomized, controlled study of Training Executive, Attention, and Motor Skills (TEAMS) in Danish preschool children with attention-deficit/hyperactivity disorder: Rationale and description of the intervention and study protocol [PDF]
Helle Annette Vibholm+3 more
doaj +1 more source
Use of a common software system for collaborative clinical research on attentional processes in schizophrenia and ADHD [PDF]
James M. Swanson+10 more
openalex +1 more source
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao+7 more
wiley +1 more source