Results 191 to 200 of about 85,712 (243)

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Plaque removal using powered and manual toothbrushes in children with and without attention deficit hyperactivity disorder: a randomized controlled trial. [PDF]

BMC Oral Health
Ucar Z, Akyildiz BM.
europepmc   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Maternal smoking based on pre-birth health examination and risk of neurodevelopmental disorders in offspring: insights from a Korean mother-child cohort. [PDF]

BMC Med
Park CS, Jang M, Kim B, Kwak S, Rhee TM, Lee H, Kim HK, Kim YJ, Kim JW, Han K, Park JB.   +10 more
europepmc   +1 more source

Klotho as a novel biomarker of attention-deficit hyperactivity disorder and related executive dysfunction. [PDF]

BJPsych Open
Chen MH, Chen LC, Hsu JW, Bai YM, Tsai SJ.   +4 more
europepmc   +1 more source

Perceived School Fairness and Academic Functioning in Early Adolescents: Differential Associations for Adolescents with or Without ADHD? [PDF]

Res Child Adolesc Psychopathol
Martinez AC, Green CD, Peugh JL, Becker SP.   +3 more
europepmc   +1 more source

Digital health technologies for adults with ADHD: a scoping review. [PDF]

Front Digit Health
Schofield FJ, Wilkie S, Nielsen EE, Brigden A, Jones MW, Isotalus HK.   +5 more
europepmc   +1 more source

A Digital Tool for Assessing the Distinct Effects of Depression, Anxiety, and Attention-Deficit/Hyperactivity Disorder (ADHD) on Children's Emotional Cognitive Bias: Cross-Sectional Study.

J Med Internet Res
Park SE, Chung J, Lee SA.
europepmc   +1 more source