Results 101 to 110 of about 2,050,017 (297)

Barriers to Pediatric Sickle Cell Disease Guideline Recommendations. [PDF]

, 2019
National guidelines recommend that providers counsel all patients with sickle cell anemia about hydroxyurea (HU) therapy and screen children with sickle cell anemia annually for the risk of stroke with transcranial Doppler (TCD).
Bardach, Naomi S, Cabana, Michael D, Kanter, Julie, Marsh, Anne M, Rowland, Michael, Stemmler, Peggy, Treadwell, Marsha J   +6 more
core  

Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion

FEBS Open Bio, EarlyView.
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng, Souvik Datta, Derrick R. Samuelson   +2 more
wiley   +1 more source

Factors contributing to preventing malaria in children aged 3 to 59 months after the first cycle of seasonal malaria chemoprevention in Tenkodogo Health District of Burkina Faso, July 2020: A prospective cohort study

Journal of Interventional Epidemiology and Public Health
Background: The incidence of malaria in children under 5 years in Burkina Faso was 163 per 1000 with a case fatality of 1.5% in 2018. Despite the implementation of several strategies, malaria incidence increased in Tenkodogo Health District after the ...
Yewayan Larba Berenger Kabore, Watton Rodrigue Diao, Dénis Yelbeogo, Arouna Koidima, Lassane Kafando, Fréderic Dianda, Noaga Sawadogo, Jean-Baptiste Ouedraogo, Yamregma Kabore, Fréderic Kambou, Kodo Albassa, Salfo Ouedraogo, Brahima Traore, Pedwinde Hamadou Seogo   +13 more
doaj   +1 more source

Adhere today, here tomorrow: oral bacterial adherence [PDF]

Journal of Bacteriology, 1993
P E, Kolenbrander, J, London
openaire   +2 more sources

Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells

FEBS Open Bio, EarlyView.
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca, Anna Tricarico, Martina Furfaro, Priyam Ghosh, Ennio Prosperi, Lucia Anna Stivala, Ornella Cazzalini   +6 more
wiley   +1 more source

COVID-19 pandemic versus six “A”s of health care services – accessibility, affordability, availability, appropriateness, adequacy, and adherence

Journal of Family Medicine and Primary Care
Background and Rationale: COVID-19 pandemic resulted in a huge setback in health care sector causing morbidity, mortality, lack of manpower, resources, in hospitals.
Kalidas Sandhya, Priyadharsini R. Palanisamy, R. Sandhya   +2 more
doaj   +1 more source

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

FEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa, Saori Kagoshima, Akira Yamada   +2 more
wiley   +1 more source

Comparing 3 Evidence‐Based Strategies to Reduce Cardiovascular Disease Burden: An Individual‐Based Cardiometabolic Policy Simulation

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Understanding the real‐world impact of clinical trials that change risk factors is important for health policy. We developed a microsimulation that estimates the population‐level benefits in each US state of cardiometabolic interventions ...
Sylvia Lutze, Steve Bachmeier, Alison Bowman, Nicole DeCleene, Hussain Jafari, Matthew Kappel, Caroline Kinuthia, Paulina Lindstedt, Megan Lindstrom, Rajan Mudambi, Christian Razo, Kjell Swedin, Abraham Flaxman, Gregory Roth   +13 more
doaj   +1 more source

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

FEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel, Sam Bennett, Natalie Ehlinger, Nelson Cook, Katelyn Marvin, Caleb L. Lines, Sam Reyes, Brooke Kirby, Shawn M. Ellerbroek   +8 more
wiley   +1 more source

Impact of patient counseling on medication adherence and drug resistance patterns in tuberculosis patients

Monaldi Archives for Chest Disease
Tuberculosis (TB) remains a primary global health concern, with non-adherence to anti-TB therapy contributing to prolonged infectiousness, treatment failure, and unfavorable outcomes. Despite established treatment protocols, adherence remains suboptimal
Sanatkumar Bharamu Nyamagoud, Princy Domnic Dsouza, Sai Phalguna Prakash Chitralu, Kadambari Solankure, Agadi Hiremath Viswanatha Swamy   +4 more
doaj   +1 more source