Results 61 to 70 of about 847,397 (199)

FimH and Anti-Adhesive Therapeutics: A Disarming Strategy Against Uropathogens

Antibiotics, 2020
Chaperone-usher fimbrial adhesins are powerful weapons against the uropathogens that allow the establishment of urinary tract infections (UTIs). As the antibiotic therapeutic strategy has become less effective in the treatment of uropathogen-related UTIs,
Meysam Sarshar, Payam Behzadi, Cecilia Ambrosi, Carlo Zagaglia, Anna Teresa Palamara, Daniela Scribano   +5 more
doaj   +1 more source

Zinc‐stabilized stannous fluoride modulates the periodontal microbiome, reducing Fusobacteria, key Gram‐negative species, and overall inflammation within an experimental gingivitis clinical trial

Journal of Periodontology, EarlyView.
Abstract Background This study aimed to evaluate the effects of a dentifrice containing stannous fluoride stabilized with zinc phosphate on subgingival microbiome composition and clinical inflammation during experimental gingivitis, compared with a sodium fluoride control. Methods This investigation was conducted as a secondary analysis of a randomized,
Kristopher A. Kerns, Allison A. Naumann, Lay Y. Soon, Erik L. Hendrickson, Abdelahhad Barbour, Dandan Chen, Harsh M. Trivedi, Michael Glogauer, Jeffrey S. McLean   +8 more
wiley   +1 more source

Large-Scale Discovery of Microbial Fibrillar Adhesins and Identification of Novel Members of Adhesive Domain Families

, 2022
Fibrillar adhesins are bacterial cell surface proteins that mediate interactions with the environment, including host cells during colonization or other bacteria during biofilm formation.
Bateman, Alex, Monzon, Vivian
core   +1 more source

adhesiomeR: a tool for Escherichia coli adhesin classification and analysis

BMC Genomics
Adhesins are crucial factors in the virulence of bacterial pathogens such as Escherichia coli. However, to date no resources have been dedicated to the detailed analysis of E. coli adhesins.
Katarzyna Sidorczuk, Michał Burdukiewicz, Klara Cerk, Joachim Fritscher, Robert A. Kingsley, Peter Schierack, Falk Hildebrand, Rafał Kolenda   +7 more
doaj   +1 more source

Identification of Tp0751 (Pallilysin) as a Treponema pallidum Vascular Adhesin by Heterologous Expression in the Lyme disease Spirochete

Scientific Reports, 2017
Treponema pallidum subsp. pallidum, the causative agent of syphilis, is a highly invasive spirochete pathogen that uses the vasculature to disseminate throughout the body.
Wei-Chien Andrew Kao, Helena Pětrošová, Rhodaba Ebady, Karen V. Lithgow, Pablo Rojas, Yang Zhang, Yae-Eun Kim, Yae-Ram Kim, Tanya Odisho, Nupur Gupta, Annette Moter, Caroline E. Cameron, Tara J. Moriarty   +12 more
doaj   +1 more source

Stuck in the Middle: Fibronectin-Binding Proteins in Gram-Positive Bacteria

Frontiers in Microbiology, 2016
Fibronectin is a multidomain glycoprotein found ubiquitously in human body fluids and extracellular matrices of a variety of cell types from all human tissues and organs, including intestinal epithelial cells.
jeffrey Hymes, Todd Klaenhammer
doaj   +1 more source

Bacterial Adhesins: Common Themes and Variations in Architecture and Assembly [PDF]

Journal of Bacteriology, 1999
Among the earliest events in many bacterial infections are the molecular interactions that occur between the pathogen and host cells. These interactions are typically required for extracellular colonization or internalization to occur and may involve a complex cascade of molecular cross talk at ...
G E, Soto, S J, Hultgren
openaire   +2 more sources

Nonthermal plasma approaches for combating implant‐associated infections: A compendious review

VIEW, EarlyView.
Implant‐associated infections pose serious clinical challenges. Non‐thermal plasma (NTP) modifications overcome this bottleneck in distinct ways relative to traditional sterilization methods. Gas‐phase plasmas generate highly energetic species, UV radiation and reactive oxygen/nitrogen species (RONS), which alter the implant surface properties.
A. M. Trimukhe, Satish Rojekar, Amol Gholap, K. Navaneetha Pandiyaraj, Mukesh Patekar, Claudia Riccardi, R. R. Deshmukh, Tomáš Kovářík, Kalim Deshmukh   +8 more
wiley   +1 more source

Localization of adhesins on the surface of a pathogenic bacterial envelope through atomic force microscopy [PDF]

, 2015
Bacterial adhesion is the first and a significant step in establishing infection. This adhesion normally occurs in the presence of flow of fluids. Therefore, bacterial adhesins must be able to provide high strength interactions with their target surface ...
Salvarezza, R. C., Kasas, S., Stupar, P., Cattelan, N., Castez, Marcos Federico, Arnal, Laura, Vela, M. E., Castez, M. F., Vela, Maria Elena, Longo, G., Cattelan, Natalia, Yantorno, O. M., Arnal, L., Yantorno, Osvaldo Miguel, Salvarezza, Roberto Carlos   +14 more
core   +1 more source

The association of surface adhesin genes and the biofilm formation among Klebsiella oxytoca clinical isolates

New Microbes and New Infections, 2019
Bacterial adhesins mediate the attachment and biofilm production leading to the persistence of colonized strains. The aim of this study was evaluation of the association of surface adhesin genes with the biofilm formation among Klebsiella oxytoca ...
A. Ghasemian, A.M. Mobarez, S.N. Peerayeh, A.T. Bezmin Abadi   +3 more
doaj   +1 more source