Results 101 to 110 of about 503,709 (238)
Recent progress in enterotoxigenic Escherichia coli vaccine research and development
There are no licensed vaccines against enterotoxigenic Escherichia coli (ETEC), a group of E. coli strains that produce a heat-labile toxin and/or a heat-stable toxin (STa). ETEC is one of the top four leading causes of diarrhea in children in developing
Weiping Zhang, David A. Sack
doaj +1 more source
Whole genome sequencing of an ExPEC that caused fatal pneumonia at a pig farm in Changchun, China
Background In recent years, highly frequent swine respiratory diseases have been caused by extraintestinal pathogenic Escherichia coli (ExPEC) in China. Due to this increase in ExPECs, this bacterial pathogen has become a threat to the development of the
Ling-Cong Kong +6 more
doaj +1 more source
Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa +3 more
wiley +1 more source
Multi‐Targeting Carnosic Acid Kills Drug‐Resistant Helicobacter pylori With Narrow‐Spectrum Activity
Carnosic acid selectively eradicates drug‐resistant Helicobacter pylori through a multi‐targeted mechanism involving urease inhibition, membrane disruption, and biofilm eradication. It exhibits no detectable resistance, potent in vivo efficacy, and minimal impact on gut microbiota, positioning it as a promising narrow‐spectrum lead compound against ...
Yuefan Bai +7 more
wiley +1 more source
Crystal structure of the P pilus rod subunit PapA [PDF]
P pili are important adhesive fibres involved in kidney infection by uropathogenic Escherichia coli strains. P pili are assembled by the conserved chaperone-usher pathway, which involves the PapD chaperone and the PapC usher.
Bullitt, E +12 more
core +1 more source
Introduction: The severity of urinary tract infection (UTI) produced by uropathogenic Escherichia coli (UPEC) is due to the expression of a wide spectrum of virulence genes. E.
Yandag Munkhdelger +4 more
doaj +1 more source
ABSTRACT The dynamic interplay between bacteria and host cancer cells plays a critical role in tumor microenvironment modulation, bacterial pathogenesis, and potential oncotherapy applications. However, traditional methods often fail to capture transient or spatially restricted molecular interactions at the bacteria‐cancer cell interface.
Amin Sun +6 more
wiley +1 more source
The lytB gene of Escherichia coli is essential and specifies a product needed for isoprenoid biosynthesis [PDF]
LytB and GcpE, because they are codistributed with other pathway enzymes, have been predicted to catalyze unknown steps in the nonmevalonate pathway for isoprenoid biosynthesis.
McLennan, Neil +3 more
core
Citrus hystrix DC. (kaffir lime) peel was dried and subjected to ethanolic extract. The GC‐MS analysis showed the presence of significant phyto‐ingredients. Pharmacokinetic and ADMET filters were applied to major constituents, and molecular docking, Gene Ontology (GO), and KEGG pathway enrichment analyses on mechanistic plausibility were also performed.
Malathy Soundara Rajan +2 more
wiley +1 more source
Remission of histiocytic ulcerative colitis in Boxer dogs correlates with eradication of invasive intramucosal Escherichia coli [PDF]
BACKGROUND: Historically, histiocytic ulcerative (HUC) (or granulomatous) colitis of Boxer dogs was considered an idiopathic immune-mediated disease with a poor prognosis. Recent reports of dramatic responses to enrofloxacin and the discovery of invasive
Dogan, B. +8 more
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