Results 1 to 10 of about 6,718 (165)
The Novel Type 1 Fimbriae FimH Receptor Calreticulin Plays a Role in Salmonella Host Specificity [PDF]
Frontiers in Cellular and Infection Microbiology, 2017 It was suggested that minor differences in the structure of FimH are most likely associated with differences in its adhesion specificities and may determine the tropism of various Salmonella serovars to different species and tissues.
Krzysztof Grzymajło +2 more
exaly +4 more sources
FimH and Anti-Adhesive Therapeutics: A Disarming Strategy Against Uropathogens [PDF]
Antibiotics, 2020 Chaperone-usher fimbrial adhesins are powerful weapons against the uropathogens that allow the establishment of urinary tract infections (UTIs). As the antibiotic therapeutic strategy has become less effective in the treatment of uropathogen-related UTIs,
Meysam Sarshar +2 more
exaly +4 more sources
Escherichia coli adhesion protein FimH exacerbates colitis via CD11b+CD103- dendritic cell activation [PDF]
Frontiers in Immunology, 2023 IntroductionImmune stimulators are used to improve vaccine efficiency; however, they are accompanied by various side effects. In previous studies, we reported that the Escherichia coli adhesion protein, FimH, induces immune activity; however, we did not ...
Wei Zhang +5 more
doaj +2 more sources
D-Mannoside FimH Inhibitors as Non-Antibiotic Alternatives for Uropathogenic Escherichia coli
Antibiotics, 2021 FimH is a type I fimbria of uropathogenic Escherichia coli (UPEC), recognized for its ability to adhere and infect epithelial urinary tissue. Due to its role in the virulence of UPEC, several therapeutic strategies have focused on the study of FimH ...
Alfredo Montes-Robledo +2 more
doaj +2 more sources
PLoS PathogensAdhesion of E. coli to the urinary tract epithelium is a critical step in establishing urinary tract infections. FimH is an adhesin positioned on the fimbrial tip which binds to mannosylated proteins on the urinary tract epithelium via its lectin domain (
Natalie C Silmon de Monerri +22 more
doaj +2 more sources
Diazirine-functionalized mannosides for photoaffinity labeling: trouble with FimH
Beilstein Journal of Organic Chemistry, 2018 Photoaffinity labeling is frequently employed for the investigation of ligand–receptor interactions in solution. We have employed an interdisciplinary methodology to achieve facile photolabeling of the lectin FimH, which is a bacterial protein, crucial ...
Femke Beiroth +5 more
doaj +2 more sources
PLoS Pathogens, 2013 Adherent-invasive Escherichia coli (AIEC) are abnormally predominant on Crohn's disease (CD) ileal mucosa. AIEC reference strain LF82 adheres to ileal enterocytes via the common type 1 pili adhesin FimH and recognizes CEACAM6 receptors abnormally ...
Nicolas Dreux +13 more
doaj +2 more sources
En route to photoaffinity labeling of the bacterial lectin FimH
Beilstein Journal of Organic Chemistry, 2010 Mannose-specific adhesion of Escherichia coli bacteria to cell surfaces, the cause of various infections, is mediated by a fimbrial lectin, called FimH.
Thisbe K. Lindhorst +3 more
doaj +2 more sources
Genotype detection of fimH gene of Acinetobacter baumannii isolated from different clinical cases
مجلة مركز بحوث التقنيات الاحيائية, 2019 Background: Forty isolates were obtained of Acinetobacter baumannii from (200) samples, the samples were collected from different cases including: - wounds, burns, Stool, Urinary tract infection urine. Aim of study: The aim of study is to isolate and
Rana M. Abdullah, Rasha Z. Ahmed
doaj +3 more sources
Modulation of Quorum Sensing and Virulence Gene Expression in Escherichia coli by Extracts of Physalis alkekengi. [PDF]
Environ Microbiol RepRoot extracts of Physalis alkekengi were examined for activity against multidrug‐resistant (MDR) Escherichia coli. The ethanolic extract suppressed bacterial growth, lowered biofilm formation by ~63%, and markedly reduced expression of luxS and fimH. Findings highlight P.
Doolaby ME +2 more
europepmc +2 more sources