Iranian Journal of Microbiology, 2012 Background and Objectives: Urinary tract infection (UTI) is one of the most common infections in the world. The majority of UTIs are caused by Uropathogenic Escherichia coli (UPEC) strains.
Karam Mr Asadi +3 more
doaj +1 more source
Interplay Between Virulence Genes, Antimicrobial Resistance Profiles, and Biofilm Formation in Klebsiella pneumoniae Causing Urinary Tract Infections in North Lebanon. [PDF]
Microbiologyopen– Figure design (single panel) Central icon: K. pneumoniae cell Left panel – Virulence genes (icons): Adhesion: fimH, mrkD → strong biofilm Capsule/regulation: magA, rmpA Siderophores: entB, iucA → iron uptake Right panel – Outcomes: Biofilm strength (weak → strong gradient) Antibiotic resistance (ESBL, MDR) Bottom split: Hospital‐acquired → strong ...
Zaylaa M +8 more
europepmc +2 more sources
Determination of Effective Prophylactic Responses of Truncated Flagellin Protein as a Vaccine Candidate Against Uropathogenic <i>Escherichia coli</i>. [PDF]
Int J MicrobiolUropathogenic Escherichia coli (UPEC) is a major cause of more than 80% of urinary tract infections (UTIs), a global health problem, and the second most common infectious disease. UTIs are responsible for approximately 40% of all nosocomial infections and 50% of all bacteremia.
Dehvari A +7 more
europepmc +2 more sources
Detection of fimH virulence gene in uropathogenic Escherichia coli Using PCR [PDF]
مجلة جامعة الانبار للعلوم الصرفة, 2020 Urinary tract infections (UTIs) are one of main health problems caused by many microorganisms, including uropathogenic Escherichia coli (UPEC). The virulence factors are important in colonization of UPEC, extra-intestinal survival, and creation of ...
Rawan Amer Fadhil
doaj +1 more source
Human Vaccines & Immunotherapeutics, 2021 Recurrent urinary tract infections (rUTI) are a serious disease associated with morbidities and mortality. Resistance to the standard of care antibiotics is now widespread because of the continued use of antibiotics among people who suffer from rUTI.
Courtney M. Starks +5 more
doaj +1 more source
DETECTION FIMH AND PAPG GENES OF ESCHERICHIA COLI AND KLEBSIELLA PNEUMONIA ISOLATED FROM GALLSTONE , URINE STONE AND GASTROINTESTINAL CANAL BY POLYMERASE CHAIN REACTION (PCR) . [PDF]
مجلة جامعة الانبار للعلوم الصرفة, 2013 During this work twenty six isolates of Escherichia coli were collected (12 from gallstones , 10 from urin stones and 4 from gastrointestinal canal) and 14 isolates of Klebsiella pneumonia (4 from gallstones , 6 from urine stones and 4 from ...
MUTHANA BADEEA FARHAN +2 more
doaj +1 more source
Human Vaccines & Immunotherapeutics, 2021 Antibiotic resistance among gram-negative bacteria continues to rise globally at an alarming rate. New vaccines that prevent bacterial infections and reduce antibiotic use could provide a potential solution to these problems.
Gary R. Eldridge +10 more
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Molecules, 2020 Urinary tract infections (UTIs) are mainly caused by uropathogenic Escherichia coli (UPEC). Acute and recurrent UTIs are commonly treated with antibiotics, the efficacy of which is limited by the emergence of antibiotic resistant strains.
Daniela Scribano +7 more
doaj +1 more source
A host receptor enables type 1 pilus-mediated pathogenesis of Escherichia coli pyelonephritis.
PLoS Pathogens, 2021 Type 1 pili have long been considered the major virulence factor enabling colonization of the urinary bladder by uropathogenic Escherichia coli (UPEC). The molecular pathogenesis of pyelonephritis is less well characterized, due to previous limitations ...
Lisa K McLellan +12 more
doaj +1 more source
FimH adhesin of type 1 fimbriae is a potent inducer of innate antimicrobial responses which requires TLR4 and type 1 interferon signalling. [PDF]
PLoS Pathogens, 2008 Components of bacteria have been shown to induce innate antiviral immunity via Toll-like receptors (TLRs). We have recently shown that FimH, the adhesin portion of type 1 fimbria, can induce the innate immune system via TLR4.
Ali A Ashkar +4 more
doaj +1 more source