Results 41 to 50 of about 7,588 (203)

Diagnosis of postpartum endometritis in dairy cows using a portable endovideo-vaginoscope with pcr confirmation [PDF]

Kafkas Universitesi Veteriner Fakültesi Dergisi
Endometritis remains a major cause of reduced reproductive efficiency in dairy cattle, necessitating practical methods for clinical detection and identification of bacterial etiology under farm conditions.
Dauletbek MURATBAYEV, Yernur SAKHARIYEV, Shynar TASTEMIROVA, Isatai JAKUPOV, Ainur AKHMADIYEVA, Cihan KACAR, Yavuz OZTURKLER   +6 more
doaj   +1 more source

Conserved FimH mutations in the global Escherichia coli ST131 multi-drug resistant lineage weaken interdomain interactions and alter adhesin function

Computational and Structural Biotechnology Journal, 2022
The binding of the type 1 fimbrial adhesin FimH to mannosylated receptors is allosterically regulated to enhance the fitness of uropathogenic Escherichia coli (UPEC) during urinary tract infection (UTI).
Jilong Qin, Katie A. Wilson, Sohinee Sarkar, Begoña Heras, Megan L. O'Mara, Makrina Totsika   +5 more
doaj   +1 more source

Comparative Study of Aryl O-, C-, and S-Mannopyranosides as Potential Adhesion Inhibitors toward Uropathogenic E. coli FimH

Molecules, 2019
A set of three mannopyranoside possessing identical 1,1′-biphenyl glycosidic pharmacophore but different aglyconic atoms were synthesized using either a palladium-catalyzed Heck cross coupling reaction or a metathesis reaction between their ...
Leila Mousavifar, Gérard Vergoten, Guillaume Charron, René Roy   +3 more
doaj   +1 more source

Escherichia coli K1 RS218 Interacts with Human Brain Microvascular Endothelial Cells via Type 1 Fimbria Bacteria in the Fimbriated State [PDF]

, 2005
Escherichia coli K1 is a major gram-negative organism causing neonatal meningitis. E. coli K1 binding to and invasion of human brain microvascular endothelial cells (HBMEC) are a prerequisite for E.
Shin, S., Kim, K.J., di Cello, F., Cai, M., Khan, Naveed Ahmed, Xie, Y., Kim, K.S., Teng, C.H.   +7 more
core   +1 more source

Expression of E. coli FimH Enhances Trafficking of an Orally Delivered Lactobacillus acidophilus Vaccine to Immune Inductive Sites via Antigen-Presenting Cells

Vaccines, 2023
The development of lactic acid bacteria as mucosal vaccine vectors requires the identification of robust mucosal adjuvants to increase vaccine effectiveness. The E.
Allison C. Vilander, Kimberly Shelton, Alora LaVoy, Gregg A. Dean   +3 more
doaj   +1 more source

FimH family of type 1 fimbrial adhesins: functional heterogeneity due to minor sequence variations among fimH genes [PDF]

Journal of Bacteriology, 1994
We recently reported that the type 1-fimbriated Escherichia coli strains CSH-50 and HB101(pPKL4), both K-12 derivatives, have different patterns of adhesion to yeast mannan, human plasma fibronectin, and fibronectin derivatives, suggesting functional heterogeneity of type 1 fimbriae.
E V, Sokurenko, H S, Courtney, D E, Ohman, P, Klemm, D L, Hasty   +4 more
openaire   +2 more sources

Frequency of fimH, papC, and aer in E. coli Strains Isolated from Patients with Urinary Tract Infection, and their Antibiotic Resistance Pattern

Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd, 2021
Introduction: E. coli is the predominant causes of urinary tract infection. Several virulence factors for bacterial infections in the urinary tract are required.
Zahra Abdolahzadeh, Akram Astani, Ahmad Mosadegh, Saeede Sadat Hosseini Mohammad Abadi, Mahmoud Vakili   +4 more
doaj  

Interplay Between Virulence Genes, Antimicrobial Resistance Profiles, and Biofilm Formation in Klebsiella pneumoniae Causing Urinary Tract Infections in North Lebanon. [PDF]

Microbiologyopen
– Figure design (single panel) Central icon: K. pneumoniae cell Left panel – Virulence genes (icons): Adhesion: fimH, mrkD → strong biofilm Capsule/regulation: magA, rmpA Siderophores: entB, iucA → iron uptake Right panel – Outcomes: Biofilm strength (weak → strong gradient) Antibiotic resistance (ESBL, MDR) Bottom split: Hospital‐acquired → strong ...
Zaylaa M, Farha R, Taleb J, Saad A, Gharbawy OE, Sarraf R, Kassam I, Hamdach C, Bissar N.   +8 more
europepmc   +2 more sources

In pursuit of a novel UTI treatment strategy - an "in silico" study of the FimH adhesin [PDF]

, 2013
Carbohydrate-binding proteins (particularly lectins) are frequent targets of present pharmaceutical research. While of high priority due to their involvement in an array of pathophysiological events, these systems (along with their saccharidic ligands)
Zalewski, Adam
core   +1 more source

Surface Labeling with Adhesion Protein FimH Improves Binding of Immunotherapeutic Agent Ty21a to the Bladder Epithelium

Bladder Cancer, 2021
BACKGROUND: Bladder cancer is the ninth most common cancer in men. 70% of these tumors are classified as non-muscle invasive bladder cancer and those patients receive 6 intravesical instillations with Mycobacterium bovis BCG after transurethral resection.
Maroeska J. Burggraaf, Lisette Waanders, Mariska Verlaan, Janneke Maaskant, Diane Houben, Joen Luirink, Wilbert Bitter, Coen Kuijl, Carla F.M. Molthoff   +8 more
doaj   +1 more source