Results 51 to 60 of about 7,588 (203)
Insightful Improvement in the Design of Potent Uropathogenic E. coli FimH Antagonists
Selective antiadhesion antagonists of Uropathogenic Escherichia coli (UPEC) type-1 Fimbrial adhesin (FimH) are attractive alternatives for antibiotic therapies and prophylaxes against acute or recurrent urinary tract infections (UTIs) caused by UPECs.
Leila Mousavifar +10 more
doaj +1 more source
Construction of fimH chromosomal mutants.
(A) Construction of fimH chromosomal mutants. (B) Electron microscopy examination of AIEC LF82 bacteria, LF82-ΔfimH isogenic mutant, LF82-ΔfimH/fimHLF82, LF82-ΔfimH/fimHK12, LF82-ΔfimH/fimH7082, LF82-ΔfimH/fimHLF28, LF82-ΔfimH/fimHLF16, LF82-ΔfimH ...
Jérémy Denizot (209615) +13 more
core +1 more source
Carbohydrate recognition is fundamental to a plethora of cellular processes and hence the elucidation of the structural determinants of the recognition process is a prerequisite for understanding and manipulating carbohydrate–protein interactions, such ...
Leon M. Friedrich, Thisbe K. Lindhorst
doaj +1 more source
ABSTRACT Malayan pangolin populations have fallen to a critically endangered level, and illegal trafficking of wild pangolins is a global problem. Little is known about antimicrobial‐resistant bacteria (MDRB) harbored by pangolins, although pangolins are frequently consumed as food or used in traditional medicine. In this study, we report for the first
Yawen Wang +8 more
wiley +1 more source
(A) Quantification of LF82-ΔfimH/fimHLF82 (black square), LF82-ΔfimH/fimH7082 (white circle), LF82-ΔfimH/fimHK12 (white square) and LF82-ΔfimH/fimHLF28 (white triangle) bacteria in the feces of CEABAC10 mice infected with 109 bacteria on day 3 post ...
Jérémy Denizot (209615) +13 more
core +1 more source
Periodontitis and Inflammatory Bowel Diseases: Mechanistic Evidence
This review aims to provide a conceptual framework for understanding the mechanistic interplay between periodontitis and IBD, with a particular emphasis on the microbial and immunological crosstalk linking the oral cavity and the gastrointestinal tract.
Ana Paula V. Colombo +3 more
wiley +1 more source
ABSTRACT Most colorectal cancers (CRCs) arise from polyps that develop malignant traits over time. As the majority of these are sporadic, environmental determinants including the gut microbiota are increasingly implicated. Dysbiosis is consistently observed in CRC; however, its association with precancerous polyps is less defined.
Michael Chieng +4 more
wiley +1 more source
Effect of antibody binding on FimH conformation.
Binding of the active state-specific mAb21 (biotinylated) to fimbrial FimHwt (A) and FimHA188D (B) after pre-treatment with 1% (52 mM) mannose, 50 μg/ml mAb475, or mAb926.
Della Friend (463416) +13 more
core +1 more source
Intermittent catheter use can damage the urinary tract and predispose to infection. We deployed a complex human urothelial model to investigate. Catheter contact induced compressive and shear stress causing umbrella cell disruption, reduced barrier function, inflammation and increased cell adhesion to the catheter surface.
Nazila V. Jafari, Jennifer L. Rohn
wiley +1 more source
Genotype detection of fimH gene of Acinetobacter baumannii isolated from different clinical cases
Background: Forty isolates were obtained of Acinetobacter baumannii from (200) samples, the samples were collected from different cases including: - wounds, burns, Stool, Urinary tract infection urine. Aim of study: The aim of study is to isolate and
Rana M. Abdullah, Rasha Z. Ahmed
doaj +1 more source

