Results 61 to 70 of about 14,945 (190)

A multi-epitope fusion antigen candidate vaccine for Enterotoxigenic Escherichia coli is protective against strain B7A colonization in a rabbit model.

PLoS Neglected Tropical Diseases, 2022
Enterotoxigenic Escherichia coli (ETEC) strains are a leading cause of children's and travelers' diarrhea. Developing effective vaccines against this heterologous group has proven difficult due to the varied nature of toxins and adhesins that determine ...
Richard M Jones, Hyesuk Seo, Weiping Zhang, David A Sack   +3 more
doaj   +1 more source

The Oral‐Gut Axis: Bidirectional Interactions Between Microbiome and Diseases

Journal of Periodontal Research, EarlyView.
This study aims to summarize the mechanisms underlying ectopic colonization of the gut by oral pathobionts and the microbial and host factors that regulate this process. ABSTRACT Increased colonization of typically oral microorganisms is frequently observed in the gut mucosa or lumen of individuals with gastrointestinal disorders, including patients ...
Shinya Ebihara, Nobuhiko Kamada
wiley   +1 more source

Fimbrial Adhesins Produced by Atypical Enteropathogenic Escherichia coli Strains [PDF]

Applied and Environmental Microbiology, 2011
ABSTRACT Atypical enteropathogenic Escherichia coli (aEPEC) has emerged as a significant cause of pediatric diarrhea worldwide; however, information regarding its adherence mechanisms to the human gut mucosa is lacking. In this study, we investigated the prevalence of several ( fimA
Hernandes, Rodrigo T. UNIFESP, Velsko, Irina, Sampaio, Suely C. F. UNIFESP, Elias Junior, Waldir Pereira UNIFESP, Robins-Browne, Roy M., Gomes, Tania A. T. UNIFESP, Giron, Jorge A.   +6 more
openaire   +3 more sources

Periodontitis and Inflammatory Bowel Diseases: Mechanistic Evidence

Journal of Periodontal Research, EarlyView.
This review aims to provide a conceptual framework for understanding the mechanistic interplay between periodontitis and IBD, with a particular emphasis on the microbial and immunological crosstalk linking the oral cavity and the gastrointestinal tract.
Ana Paula V. Colombo, Adriana M. de Oliveira, Nobuhiko Kamada, Sho Kitamoto   +3 more
wiley   +1 more source

Oral Health, Periodontitis, and Respiratory Diseases: Biological Pathways

Journal of Periodontal Research, EarlyView.
This narrative review aims to provide a comprehensive update on the potential mechanisms by which poor oral health and periodontitis impact lung health, focusing on pneumonia, COPD, and asthma. ABSTRACT Poor oral hygiene and periodontitis influence lung diseases such as pneumonia, chronic obstructive pulmonary disease (COPD), COVID‐19, and asthma.
Raluca P. Vacaru, Andreea C. Didilescu, Frank A. Scannapieco   +2 more
wiley   +1 more source

Compounds targeting YadC of uropathogenic Escherichia coli and its host receptor annexin A2 decrease bacterial colonization in bladder

EBioMedicine, 2019
Background: Uropathogenic Escherichia coli (UPEC) is the leading cause of urinary tract infections (UTIs), and fimbrial tip adhesins, play important roles in UPEC colonization.
Xiao Li, Geng Pei, Lisong Zhang, Yang Cao, Jingyu Wang, Lu Yu, Wei Dianjun, Shan Gao, Zhi-Song Zhang, Zhi Yao, Quan Wang   +10 more
doaj   +1 more source

Artificial Catch Bonds: From Molecular Design to Network Mechanics

ChemSystemsChem, Volume 8, Issue 5, September 2026.
Catch bonds strengthen rather than weaken under force. This review follows the discovery and development of our understanding of this counterintuitive phenomenon, from the molecular mechanisms that produce it to the design rules for engineering it in DNA, proteins, and polymers, and on to the collective network mechanics enabling materials that stiffen
Hengfeng Jiang, Micah Yang, Isaac T. S. Li   +2 more
wiley   +1 more source

Postbiotics in Food Systems: Components, Production Methods, Food Applications, Functional Properties, and Technological Challenges

Food Science &Nutrition, Volume 14, Issue 8, August 2026.
This review provides a comprehensive, engineering‐oriented synthesis of postbiotics as next‐generation functional food ingredients. It first outlines the principal production routes for postbiotic generation, encompassing thermal technologies, non‐thermal technologies, and extraction/purification methods, and subsequently examines the analytical and ...
Tansu Taspinar, Nuray Güzeler
wiley   +1 more source

Whole genome sequencing of an ExPEC that caused fatal pneumonia at a pig farm in Changchun, China

BMC Veterinary Research, 2017
Background In recent years, highly frequent swine respiratory diseases have been caused by extraintestinal pathogenic Escherichia coli (ExPEC) in China. Due to this increase in ExPECs, this bacterial pathogen has become a threat to the development of the
Ling-Cong Kong, Xia Guo, Zi Wang, Yun-Hang Gao, Bo-Yan Jia, Shu-Ming Liu, Hong-Xia Ma   +6 more
doaj   +1 more source

Molecular genetic analysis of Escherichia coli type I adhesins

Bulletin of Experimental Biology and Medicine, 2006
Protein FimH is an adhesive terminal subunit of Escherichia coli type I pili. The content of FimH on the surface of a bacterial cell does not directly depend on FimH expression, but is limited by expression of other fim cluster genes encoding structural subunits and proteins responsible for assembly of pili.
Beskhlebnaya V.A., Aprikyan P., Chesnokova V., Sokurenko E.V., Trinchina E.V.   +4 more
openaire   +4 more sources