Results 11 to 20 of about 1,023,593 (296)

Adhesion and Adhesives [PDF]

SHINKU, 1966
Adhesion and Adhesives Edited by Dr. R. Houwink and Dr. G. Salomon. Vol. 1: Adhesives. Second, completely revised edition. Pp. xvi + 548. (Amsterdam, London and New York: Elsevier Publishing Company, 1965.) 135s.
openaire   +4 more sources

The Spike Glycoprotein of SARS-CoV-2 Binds to β1 Integrins Expressed on the Surface of Lung Epithelial Cells

Viruses, 2021
The spike glycoprotein attached to the envelope of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) binds to and exploits angiotensin-converting enzyme 2 (ACE2) as an entry receptor to infect pulmonary epithelial cells.
Eun Jeong Park, Phyoe Kyawe Myint, Michael Gyasi Appiah, Samuel Darkwah, Siqingaowa Caidengbate, Atsushi Ito, Eri Matsuo, Eiji Kawamoto, Arong Gaowa, Motomu Shimaoka   +9 more
doaj   +1 more source

Targeted remodeling of breast cancer and immune cell homing niches by exosomal integrins

Diagnostic Pathology, 2020
Exosomes represent an important subset of extracellular vesicles involved in inter-cellular communications in health and diseases. Exosomes secreted from cancer and immune cells travel to the specific tissues containing homing niches.
Phyoe Kyawe Myint, Eun Jeong Park, Arong Gaowa, Eiji Kawamoto, Motomu Shimaoka   +4 more
doaj   +1 more source

Conformational flexibility determines the Nf2/merlin tumor suppressor functions

Matrix Biology Plus, 2021
The Neurofibromatosis type 2 gene encodes the Nf2/merlin tumor suppressor protein that is responsible for the regulation of cell proliferation. Once activated, Nf2/merlin modulates adhesive signaling pathways and thereby inhibits cell growth.
Marina C. Primi, Erumbi S. Rangarajan, Dipak N. Patil, Tina Izard   +3 more
doaj   +1 more source

Sharpin suppresses β1-integrin activation by complexing with the β1 tail and kindlin-1

Cell Communication and Signaling, 2019
Background Previously sharpin has been identified as an endogenous inhibitor of β1-integrin activation by directly binding to a conserved region in the cytoplasmic tails (CTs) of the integrin β1-associated α subunits. Methods Here we employed biochemical
Juan Gao, Yun Bao, Shushu Ge, Peisen Sun, Jiaojiao Sun, Jianmin Liu, Feng Chen, Li Han, Zhongyuan Cao, Jun Qin, Gilbert C. White, Zhen Xu, Yan-Qing Ma   +12 more
doaj   +1 more source

Integrin-Ligand Interactions in Inflammation, Cancer, and Metabolic Disease: Insights Into the Multifaceted Roles of an Emerging Ligand Irisin

Frontiers in Cell and Developmental Biology, 2020
Integrins are transmembrane proteins that mediate cellular adhesion and migration to neighboring cells or the extracellular matrix, which is essential for cells to undertake diverse physiological and pathological pathways.
Eun Jeong Park, Phyoe Kyawe Myint, Atsushi Ito, Atsushi Ito, Michael G. Appiah, Samuel Darkwah, Eiji Kawamoto, Eiji Kawamoto, Motomu Shimaoka   +8 more
doaj   +1 more source

Mechanotransduction as a major driver of cell behaviour: mechanisms, and relevance to cell organization and future research

Open Biology, 2021
How do cells process environmental cues to make decisions? This simple question is still generating much experimental and theoretical work, at the border of physics, chemistry and biology, with strong implications in medicine.
Pierre-Henri Puech, Pierre Bongrand
doaj   +1 more source

Circulating LPS from gut microbiota leverages stenosis-induced deep vein thrombosis in mice

Thrombosis Journal, 2023
Objective and design An accumulating body of evidence has shown that gut microbiota is involved in regulating inflammation; however, it remains undetermined if and how gut microbiota plays an important role in modulating deep venous thrombosis (DVT ...
Cheng Liu, Ying Zhou, Huihui Gao, Zeping Zhang, Yu Zhou, Zifeng Xu, Chenhong Zhang, Zhen Xu, Huajun Zheng, Yan-Qing Ma   +9 more
doaj   +1 more source

A Method to Culture GABAergic Interneurons Derived from the Medial Ganglionic Eminence

Frontiers in Cellular Neuroscience, 2018
Understanding the mechanisms guiding interneuron development is a central aspect of the current research on cortical/hippocampal interneurons, which is highly relevant to brain function and pathology.
Sira A. Franchi, Romina Macco, Veronica Astro, Diletta Tonoli, Elisa Savino, Flavia Valtorta, Kristyna Sala, Martina Botta, Ivan de Curtis   +8 more
doaj   +1 more source

The Lectin-Like Domain of Thrombomodulin Inhibits β1 Integrin-Dependent Binding of Human Breast Cancer-Derived Cell Lines to Fibronectin

Biomedicines, 2021
Thrombomodulin is a molecule with anti-coagulant and anti-inflammatory properties. Recently, thrombomodulin was reported to be able to bind extracellular matrix proteins, such as fibronectin and collagen; however, whether thrombomodulin regulates the ...
Eiji Kawamoto, Nodoka Nago, Takayuki Okamoto, Arong Gaowa, Asami Masui-Ito, Yuichi Akama, Samuel Darkwah, Michael Gyasi Appiah, Phyoe Kyawe Myint, Gideon Obeng, Atsushi Ito, Siqingaowa Caidengbate, Ryo Esumi, Takanori Yamaguchi, Eun Jeong Park, Hiroshi Imai, Motomu Shimaoka   +16 more
doaj   +1 more source