Results 11 to 20 of about 893,418 (338)

The Spike Glycoprotein of SARS-CoV-2 Binds to β1 Integrins Expressed on the Surface of Lung Epithelial Cells

open access: yesViruses, 2021
The spike glycoprotein attached to the envelope of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) binds to and exploits angiotensin-converting enzyme 2 (ACE2) as an entry receptor to infect pulmonary epithelial cells.
Eun Jeong Park   +9 more
doaj   +1 more source

Adhesion and Adhesives [PDF]

open access: yesSHINKU, 1966
Adhesion and Adhesives Edited by Dr. R. Houwink and Dr. G. Salomon. Vol. 1: Adhesives. Second, completely revised edition. Pp. xvi + 548. (Amsterdam, London and New York: Elsevier Publishing Company, 1965.) 135s.
openaire   +4 more sources

Targeted remodeling of breast cancer and immune cell homing niches by exosomal integrins

open access: yesDiagnostic Pathology, 2020
Exosomes represent an important subset of extracellular vesicles involved in inter-cellular communications in health and diseases. Exosomes secreted from cancer and immune cells travel to the specific tissues containing homing niches.
Phyoe Kyawe Myint   +4 more
doaj   +1 more source

The mitochondrial outer membrane protein SYNJ2BP interacts with the cell adhesion molecule TMIGD1 and can recruit it to mitochondria

open access: yesBMC Molecular and Cell Biology, 2020
Background Transmembrane and immunoglobulin domain-containing protein 1 (TMIGD1) is a recently identified cell adhesion molecule which is predominantly expressed by epithelial cells of the intestine and the kidney. Its expression is downregulated in both
Christian Hartmann   +11 more
doaj   +1 more source

Sharpin suppresses β1-integrin activation by complexing with the β1 tail and kindlin-1

open access: yesCell Communication and Signaling, 2019
Background Previously sharpin has been identified as an endogenous inhibitor of β1-integrin activation by directly binding to a conserved region in the cytoplasmic tails (CTs) of the integrin β1-associated α subunits. Methods Here we employed biochemical
Juan Gao   +12 more
doaj   +1 more source

Nanoporous monolithic microsphere arrays have anti-adhesive properties independent of humidity [PDF]

open access: yesMaterials 2016, 9, 373, 2016
Bioinspired artificial surfaces with tailored adhesive properties have attracted significant interest. While fibrillar adhesive pads mimicking gecko feet are optimized for strong reversible adhesion, monolithic microsphere arrays mimicking the slippery zone of the pitchers of carnivorous plants of the genus Nepenthes show anti-adhesive properties even ...
arxiv   +1 more source

Mechanotransduction as a major driver of cell behaviour: mechanisms, and relevance to cell organization and future research

open access: yesOpen Biology, 2021
How do cells process environmental cues to make decisions? This simple question is still generating much experimental and theoretical work, at the border of physics, chemistry and biology, with strong implications in medicine.
Pierre-Henri Puech, Pierre Bongrand
doaj   +1 more source

Integrin-Ligand Interactions in Inflammation, Cancer, and Metabolic Disease: Insights Into the Multifaceted Roles of an Emerging Ligand Irisin

open access: yesFrontiers in Cell and Developmental Biology, 2020
Integrins are transmembrane proteins that mediate cellular adhesion and migration to neighboring cells or the extracellular matrix, which is essential for cells to undertake diverse physiological and pathological pathways.
Eun Jeong Park   +8 more
doaj   +1 more source

Circulating LPS from gut microbiota leverages stenosis-induced deep vein thrombosis in mice

open access: yesThrombosis Journal, 2023
Objective and design An accumulating body of evidence has shown that gut microbiota is involved in regulating inflammation; however, it remains undetermined if and how gut microbiota plays an important role in modulating deep venous thrombosis (DVT ...
Cheng Liu   +9 more
doaj   +1 more source

On/off switching of adhesion in gecko-inspired adhesives [PDF]

open access: yes, 2020
In this study, the adhesion-detachment behaviour of a gecko-inspired adhesive pad was investigated to understand the on/off switching mechanisms of adhesion in gecko feet. A macroscopic spatula model was fabricated using silicone rubber, and adhesion tests combining lateral sliding and vertical debonding were conducted. It was observed that the contact
arxiv   +1 more source

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