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Background Transmembrane and immunoglobulin domain-containing protein 1 (TMIGD1) is a recently identified cell adhesion molecule which is predominantly expressed by epithelial cells of the intestine and the kidney. Its expression is downregulated in both
Christian Hartmann+11 more
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Selective Desensitization of Growth Factor Signaling by Cell Adhesion to Fibronectin [PDF]
Cell adhesion to the extracellular matrix is required to execute growth factor (GF)-mediated cell behaviors, such as proliferation. A major underlying mechanism is that cell adhesion enhances GF-mediated intracellular signals, such as extracellular ...
Asthagiri, Anand R.+3 more
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Intercellular adhesion molecule-1
The intercellular adhesion molecule (ICAM) 1 is an Ig-like cell adhesion molecule expressed by several cell types, including leukocytes and endothelial cells.
A. Stolpe, P. V. D. Saag
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Inhibition of tumor necrosis factor α–stimulated monocyte adhesion to human aortic endothelial cells by AMP-activated protein kinase [PDF]
<b>Objective</b>— Proatherosclerotic adhesion of leukocytes to the endothelium is attenuated by NO. As AMP-activated protein kinase (AMPK) regulates endothelial NO synthesis, we investigated the modulation of adhesion to cultured human aortic
Ewart, M-A., Kohlhaas, C.F., Salt, I.P.
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Cell adhesion in cancer: Beyond the migration of single cells
Homeostasis in healthy tissues strongly relies on cell-to-cell adhesion and cell-to-extracellular matrix interactions. For instance, normal epithelial cells maintain tissue structure by adhering to each other and to the extracellular matrix. The proteins
M. Janiszewska, M. C. Primi, T. Izard
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Sharpin suppresses β1-integrin activation by complexing with the β1 tail and kindlin-1
Background Previously sharpin has been identified as an endogenous inhibitor of β1-integrin activation by directly binding to a conserved region in the cytoplasmic tails (CTs) of the integrin β1-associated α subunits. Methods Here we employed biochemical
Juan Gao+12 more
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Nucleation of membrane adhesions [PDF]
Recent experimental and theoretical studies of biomimetic membrane adhesions [Bruinsma et al., Phys. Rev. E 61, 4253 (2000); Boulbitch et al., Biophys. J.
Wang, Zhen-Gang, Zhang, Cheng-Zhong
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57 Candida glabrata , a fungal pathogen colonizing mucocutaneous membranes and indwelling 58 medical devices, is associated with invasive infections, especially in immunocompromised 59 individuals. Candidiasis could be of endogenous and exogenous origins.
Membre Associe, Personne Physique
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How do cells process environmental cues to make decisions? This simple question is still generating much experimental and theoretical work, at the border of physics, chemistry and biology, with strong implications in medicine.
Pierre-Henri Puech, Pierre Bongrand
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Twin disc assessment of wheel/rail adhesion [PDF]
Loss of adhesion between a railway wheel and the track has implications for both braking and traction. Poor adhesion in braking is a safety issue as it leads to extended stopping distances. In traction, it is a performance issue as it may lead to reduced
Gallardo-Hernandez, E.A., Lewis, R.
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