Results 21 to 30 of about 893,418 (338)
A Method to Culture GABAergic Interneurons Derived from the Medial Ganglionic Eminence
Frontiers in Cellular Neuroscience, 2018 Understanding the mechanisms guiding interneuron development is a central aspect of the current research on cortical/hippocampal interneurons, which is highly relevant to brain function and pathology.
Sira A. Franchi +8 more
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Biomedicines, 2021 Thrombomodulin is a molecule with anti-coagulant and anti-inflammatory properties. Recently, thrombomodulin was reported to be able to bind extracellular matrix proteins, such as fibronectin and collagen; however, whether thrombomodulin regulates the ...
Eiji Kawamoto +16 more
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CD8 Co-Receptor Enhances T-Cell Activation without Any Effect on Initial Attachment
Cells, 2021 The scanning of surrounding tissues by T lymphocytes to detect cognate antigens requires high speed, sensitivity and specificity. T-cell receptor (TCR) co-receptors such as CD8 increase detection performance, but the exact mechanism remains incompletely ...
Philippe Robert +3 more
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Developmental Cell, 2015 Adherens junctions (AJs) play a crucial role in epithelial tissue development and tumorigenesis, and the mechanisms controlling their assembly and disassembly have therefore attracted considerable attention. A paper from Tsur et al. (2015) in this issue of Developmental Cell now shows how sumoylation and desumoylation of E-cadherin promotes its ...
openaire +5 more sources
Differential Roles of Dendritic Cells in Expanding CD4 T Cells in Sepsis
Biomedicines, 2019 Sepsis is a systemically dysregulated inflammatory syndrome, in which dendritic cells (DCs) play a critical role in coordinating aberrant immunity. The aim of this study is to shed light on the differential roles played by systemic versus mucosal DCs in ...
Samuel Darkwah +6 more
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FAK Structure and Regulation by Membrane Interactions and Force in Focal Adhesions
Biomolecules, 2020 Focal adhesion kinase (FAK) is a non-receptor tyrosine kinase with key roles in the regulation of cell adhesion migration, proliferation and survival. In cancer FAK is a major driver of invasion and metastasis and its upregulation is associated with poor
Paula Tapial Martínez +2 more
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Adhesives and adhesion: True chemical compounds as adhesives [PDF]
Proceedings of the Royal Society of London. Series A, Containing Papers of a Mathematical and Physical Character, 1927 Adhesives are usually regarded as ill-defined substances of a colloidal nature, typified by glues, gums, resins, pastes and the like. It is the object of the present communication to show that pure substances can fully rival many of the common adhesives.
W. B. Lee, James W. McBain
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Irisin supports integrin-mediated cell adhesion of lymphocytes
Biochemistry and Biophysics Reports, 2021 Irisin, a myokine released from skeletal muscle, has recently been found to act as a ligand for the integrins αVβ5, αVβ1, and α5β1 expressed on mesenchymal cells, thereby playing an important role in the metabolic remodeling of the bone, skeletal muscle ...
Phyoe Kyawe Myint +8 more
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Theoretical limits in detachment strength for axisymmetric bi-material adhesives [PDF]
arXiv, 2021 Dry adhesives rely on short-ranged intermolecular bonds, hence requiring a low elastic modulus to conform to the surface roughness of the adhered material. Under external loads, however, soft adhesives accumulate strain energy, which release drives the propagation of interfacial flaws prompting detachment. The ideal adhesive is then soft but rigid. The
arxiv
MicroRNA Profiles in Intestinal Epithelial Cells in a Mouse Model of Sepsis
Cells, 2023 Sepsis is a systemic inflammatory disorder that leads to the dysfunction of multiple organs. In the intestine, the deregulation of the epithelial barrier contributes to the development of sepsis by triggering continuous exposure to harmful factors ...
Siqingaowa Caidengbate +9 more
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