Differential Roles of Dendritic Cells in Expanding CD4 T Cells in Sepsis
Sepsis is a systemically dysregulated inflammatory syndrome, in which dendritic cells (DCs) play a critical role in coordinating aberrant immunity. The aim of this study is to shed light on the differential roles played by systemic versus mucosal DCs in ...
Samuel Darkwah +6 more
doaj +1 more source
CD8 Co-Receptor Enhances T-Cell Activation without Any Effect on Initial Attachment
The scanning of surrounding tissues by T lymphocytes to detect cognate antigens requires high speed, sensitivity and specificity. T-cell receptor (TCR) co-receptors such as CD8 increase detection performance, but the exact mechanism remains incompletely ...
Philippe Robert +3 more
doaj +1 more source
Adhesion Induced DNA Naturation [PDF]
DNA adsorption and naturation is modeled via two interacting flexible homopolymers coupled to a solid surface. DNA denatures if the entropy gain for unbinding the two strands overcomes the loss of binding energy.
A. E. Allahverdyan +10 more
core +2 more sources
FAK Structure and Regulation by Membrane Interactions and Force in Focal Adhesions
Focal adhesion kinase (FAK) is a non-receptor tyrosine kinase with key roles in the regulation of cell adhesion migration, proliferation and survival. In cancer FAK is a major driver of invasion and metastasis and its upregulation is associated with poor
Paula Tapial Martínez +2 more
doaj +1 more source
Polypropylene mesh for hernia repair with controllable cell adhesion/de-adhesion properties [PDF]
Herein, a versatile bilayersystem, composed by a polypropylene(PP)mesh and a covalently bonded poly(N-isopropylacrylamide) (PNIPAAm) hydrogel, is reported.
Alemán Llansó, Carlos +6 more
core +2 more sources
The role of cell-cell adhesion in wound healing
We present a stochastic model which describes fronts of cells invading a wound. In the model cells can move, proliferate, and experience cell-cell adhesion.
A. Kolmogorov +18 more
core +1 more source
Cell Adhesion at the Tight Junctions: New Aspects and New Functions
Tight junctions (TJ) are cell–cell adhesive structures that define the permeability of barrier-forming epithelia and endothelia. In contrast to this seemingly static function, TJs display a surprisingly high molecular complexity and unexpected dynamic ...
Nicolina Wibbe, Klaus Ebnet
doaj +1 more source
The role of titanium in electromigrated tunnel junctions
A standard route for fabrication of nanoscopic tunnel junctions is via electromigration of lithographically prepared gold nanowires. In the lithography process, a thin adhesion layer, typically titanium, is used to promote the adhesion of the gold ...
Frimmer, Martin +3 more
core +1 more source
Loss of flotillin expression results in weakened desmosomal adhesion and Pemphigus vulgaris-like localisation of desmoglein-3 in human keratinocytes [PDF]
Desmosomes are adhesion plaques that mediate cell-cell adhesion in many tissues, including the epidermis, and generate mechanical resistance to tissues. The extracellular domains of desmosomal cadherin proteins, desmogleins and desmocollins, are required
Ali, Jawahir +7 more
core +1 more source
Adhesion attenuation and enhancement in aqueous solutions [PDF]
When two surfaces confine water layers between them at the nanoscale, the behaviour of these confined water molecules can deviate significantly from the behaviour of bulk water, and it could reflect on the adhesion of such surfaces.
Bowen, James +2 more
core

