Results 71 to 80 of about 673,565 (309)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Journal of Biomechanical Engineering, 2014 Adhesive dynamics (AD) is a method for simulating the dynamic response of biological systems in response to force. Biological bonds are mechanical entities that exert force under strain, and applying forces to biological bonds modulates their rate of dissociation.
openaire +2 more sources
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Adhesive for cryogenic temperature applications [PDF]
, 1969 Adhesive, which bonds a metal liner to a filament wound composite structure used for cryogenic pressure vessels, prevents the metal liner from buckling under depressurization.
Doyle, H. M.
core +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
On the Origin of Frictional Adhesion in Geckos: Small Morphological Changes Lead to a Major Biomechanical Transition in the Genus \u3cem\u3eGonatodes\u3c/em\u3e [PDF]
, 2017 The evolutionary history of vertebrate locomotion is punctuated by innovations that have permitted expansion into novel ecological niches. Frictional adhesion of geckos is an innovation renowned for enabling locomotion on vertical and inverted smooth ...
Gamble, Tony +2 more
core +1 more source
Adhesive Contact to a Coated Elastic Substrate [PDF]
, 2007 We show how the quasi-analytic method developed to solve linear elastic contacts to coated substrates (Perriot A. and Barthel E. {\em J. Mat. Res.}, {\bf 2004}, {\em 19}, 600) may be extended to adhesive contacts. Substrate inhomogeneity lifts accidental
A Perriot +18 more
core +2 more sources
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Fracture and Structural Integrity, 2019 In this work the finite element method was used to analyse the composite patch shape effect of the repair performance. Unlike all the works done conducted so far in this domain, this work proposed here, takes into account the reducing both, the stress ...
Baghdadi Mohammed +4 more
doaj +1 more source
, 2015 Cohesive zone models do not consider the lateral contraction of adhesive layers under tensile loads. The constraint of the lateral contraction by the adherents which depends on the geometry of the adhesive layer has a major influence on the normal ...
Hesebeck, Olaf
core +1 more source