Results 121 to 130 of about 270,585 (284)
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
Solvent resistant thermoplastic aromatic poly(imidesulfone) and process for preparing same [PDF]
, 1983 A process for preparing a thermoplastic poly(imidesulfone) is disclosed. This resulting material has thermoplastic properties which are generally associated with polysulfones but not polyimides, and solvent resistance which is generally associated with ...
St.clair, T. L., Yamaki, D. A.
core +1 more source
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Strength through diversity: how cancers thrive when clones cooperate
Molecular Oncology, EarlyView.Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
EXPERIMENTAL STUDY ON ANTI-FREEZING ADHESIVE ROLLER WITH PTFE
Jixie qiangdu, 2016 In order to study the turnabout roller coal slime freezing adhesion problem in the process of open-pit mine during winter,experimental apparatus was designed by ourselves,simulated the production site,studied the change of freezing adhesive ...
WANG ChunHua +3 more
doaj
Soybean meal-based adhesive reinforced with cellulose nano-whiskers [PDF]
BioResources, 2012 Cellulose nano-whiskers were used to enhance the performance of soybean meal-based adhesive. Soybean meal flour, cellulose nano-whiskers (CNW), sodium hydroxide (NaOH), and polyethylene glycol (PEG) were used to develop different adhesive formulations ...
Qiang Gao +4 more
doaj
Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
A cyanoacrylate direct bonding system of orthodontic attachments [PDF]
, 1973 Thesis (M.Sc.D.)--Boston University School of Graduate Dentistry, 1973.
Fasy, James J.
core
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source