Results 141 to 150 of about 272,112 (304)

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

NKCC1: A key regulator of glioblastoma progression

open access: yesMolecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen   +5 more
wiley   +1 more source

PEMBUATAN PUPUK KALIUM-FOSFAT DARI ABU KULIT KAPOK DAN TEPUNG FOSFAT SECARA GRANULASI

open access: yesTeknik, 2012
Kapok-husk ash containing + 28% potassium can be used as raw material of potassium-phosphatefertilizer. In this research, kapok-husk ash is mixed with phosphate powder by granulation process toproduce potassium-phosphate fertilizer.
Aprilina Purbasari, Faleh Setia Budi
doaj  

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Feasibility of Bio-Based Molasses and Citric Acid for The Manufacturing of Oil Palm Frond Particleboard

open access: yesBioResources
The oil palm frond (OPF) particleboard can be manufactured using bio-adhesive-based molasses and citric acid (MOCA) at different ratios. Before particleboard manufacture, each bio-adhesive was diluted in distilled water with a solid content of 59 wt% at ...
Sahriyanti Saad   +11 more
doaj  

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

O USO DA FARINHA DE Orbignya speciosa NA FORMULAÇÃO DE ADESIVO PARA COMPENSADOS

open access: yesCiência Florestal, 2014
The aim of this study was to evaluate the effect of the addition of babaçu flour on urea-formaldehyde adhesive properties and compare it to the adhesives produced with wheat flour, which is the extender usually used for plywood production. An amount of 0,
Vanessa Coelho Almeida   +3 more
doaj  

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

INFLUENCE OF PRESSURE ON COAL FREEZING ADHESIVE STRENGTH

open access: yesJixie qiangdu, 2016
Coal is the important basic energy in China,while the coal freezing adhesion seriously restricts with coal mine safe and efficient production in winter.
WANG ChunHua   +3 more
doaj  

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