Computational Design of Broad-Spectrum Ebola Antibodies through Framework and Complementarity-Determining Region Synergistic Optimization. [PDF]
Zhang X +12 more
europepmc +1 more source
Deletion of Astrocytic TNFR1 Attenuates Hyperexcitability and Initiation of Epileptogenesis
Inducible, astrocyte‐specific deletion of TNFR1 reduces basal EEG spectral power. Loss of astrocytic TNFR1 attenuates acute seizure activity in two distinct experimental models of epilepsy. Deletion of TNFR1 in astrocytes limits epilepsy development and hippocampal pathology in a mouse model of temporal lobe epilepsy with hippocampal sclerosis ...
Lukas Henning +6 more
wiley +1 more source
scAgeClock: a single-cell transcriptome-based human aging clock model using gated multi-head attention neural networks. [PDF]
Xie G.
europepmc +1 more source
ABSTRACT Background Although depressive symptoms are highly prevalent in IBD based on questionnaire estimates, the prevalence of stringently diagnosed depression in IBD is unclear. This is important because higher‐intensity treatments for depression are only recommended in this subgroup.
Liling Xiao +2 more
wiley +1 more source
Socioeconomic Disadvantage and Care Proximity Influence Stage at Presentation in Head and Neck Cancer. [PDF]
Bridgham K +7 more
europepmc +1 more source
Disparities in Hearing Screening Practices in Minnesota Elementary Schools
ABSTRACT Objective Identifying and addressing pediatric hearing loss is critical to supporting a child's development. School‐based hearing screening is a mainstay of timely identification of hearing loss. The objectives of this study were to characterize the current hearing screening practices in public, charter, and private elementary schools in ...
Autefeh Sajjadi +12 more
wiley +1 more source
Examining persistent inequities in financial complaint resolution for older Americans and veterans in the United States. [PDF]
Sun Y, He D, Kejriwal M.
europepmc +1 more source
Neighborhood Deprivation and Voice and Reflux Symptom Burden in a Tertiary Laryngology Cohort
ABSTRACT Objective The voice handicap index‐10 (VHI‐10) and reflux symptoms index (RSI) are validated, patient‐reported outcome measures (PROMs) commonly used in laryngology to assess the subjective impact of voice disorders and severity of symptoms associated with laryngopharyngeal reflux, respectively.
Sandra Stinnett +6 more
wiley +1 more source
New strategies for mitigating undesirable odors connected to geosmin and 2-MIB in minced fish muscle: a model system approach. [PDF]
Phetsang H +3 more
europepmc +1 more source

