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Nihon rinsho. Japanese journal of clinical medicine, 2007
Aimin Xu, Yu Wang, Karen S. L. Lam
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Aimin Xu, Yu Wang, Karen S. L. Lam
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Diabetes & Metabolism, 2008
The discoveries of leptin and adiponectin were breakthroughs in the field of metabolic diseases. Adipose cells produce both proteins and release them into the circulation. Leptin acts as a fundamental signal for the brain to modulate food intake as a function of energy status. Loss of leptin function results in obesity.
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The discoveries of leptin and adiponectin were breakthroughs in the field of metabolic diseases. Adipose cells produce both proteins and release them into the circulation. Leptin acts as a fundamental signal for the brain to modulate food intake as a function of energy status. Loss of leptin function results in obesity.
openaire +2 more sources
Adiponectin Resistance in Obesity: Adiponectin Leptin/Insulin Interaction
The adiponectin (APN) levels in obesity are negatively correlated with chronic subclinical inflammation markers. The hypertrophic adipocytes cause obesity-linked insulin resistance and metabolic syndrome. Furthermore, macrophage polarization is a key determinant regulating adiponectin receptor (AdipoR1/R2) expression and differential adiponectin ...openaire +2 more sources