Results 111 to 120 of about 5,616,381 (302)

High glucose-induced reactive oxygen species generation promotes sternness in human adipose-derived stem cells

open access: yes, 2017
Background aims. Adipose-derived stem cells (ASCs) represent an important source of cell therapy to treat diabetic complications. However, hyperglycemia may alter several cellular functions, so the present study aimed to investigate the influence of a ...
Cheng, Nai-Chen;Hsieh, Tsung-Yu;Lai, Hong-Shiee;Young, Tai-Horng   +1 more
core   +1 more source

Application and Single‐Cell Regulation Mechanism of Engineered EVs Combined With 4D‐Printed Hydrogel for Infected Burn Repair

open access: yesAdvanced Science, EarlyView.
4D bioprinted hydrogel loaded with FGF2‐modified extracellular vesicles (4D@F‐EVs) targets dermal fibroblasts and elevates local wound FGF2 levels via sustained release of F‐EVs. It activates PI3K‐Akt signaling, restores critical KGF+ fibroblast–KGFR+ keratinocyte crosstalk, enhances robust angiogenesis and collagen deposition to efficiently repair ...
Xiaomin Wang   +19 more
wiley   +1 more source

Omental adipose tissue is a more suitable source of canine Mesenchymal stem cells

open access: yesBMC Veterinary Research, 2017
Background Mesenchymal Stem Cells (MSCs) are a promising therapeutic tool in veterinary medicine. Currently the subcutaneous adipose tissue is the leading source of MSCs in dogs.
Francisca Bahamondes   +4 more
doaj   +1 more source

Culturas primárias de tecido adiposo humano e impacto no cancro da próstata [PDF]

open access: yes, 2009
Mestrado em Biologia Aplicada - Molecular e CelularProstate cancer (Pca) is one of the most frequent diagnosed neoplasies and the second cause of cancer-related death in the world, in men. Between others risk factors, obesity has been associated to Pca
Cunha, Virgínia Filipa Pereira Monteiro da
core  

Cell-Free Hydrogel System Based on a Tissue-Specific Extracellular Matrix for In Situ Adipose Tissue Regeneration

open access: yes, 2017
Well-designed scaffolds provide appropriate niches that can effectively recruit host cells and induce differentiation of recruited cells into the desired cell types, facilitating in situ tissue regeneration. Here we report a tissue-specific extracellular
Yong Woo Cho (758273)   +2 more
core   +1 more source

Dual‐Organelle Secretome Conjugation and Organ‐Uptake Tracking (DuO‐SCOUT) Enables Deep and Sensitive Mapping of the Secreted Proteins

open access: yesAdvanced Science, EarlyView.
A novel dual‐organelle proximity labeling platform, DuO‐SCOUT, decodes the complex landscape of systemic organ‐organ communication by capturing both classical and unconventional secretomes. Application in metabolic models maps the adipose‐to‐brain secretory relay, identifying selective extra‐hypothalamic sites for adipose‐derived factors and expanding ...
Fenglian Yang   +7 more
wiley   +1 more source

Activación de los receptores de tipo Toll en el adipocito: su influencia en el inicio y la permanencia de la obesidad

open access: yesMedisan
La obesidad infantil constituye un importante problema de salud en la actualidad, que está experimentando un incremento en todo el mundo. En las personas obesas el exceso de tejido adiposo blanco genera una respuesta inflamatoria crónica de bajo grado ...
José María Basain Valdés   +3 more
doaj  

Dissecting human adipose tissue heterogeneity using single‐cell omics technologies

open access: yesStem Cell Research & Therapy
Single-cell omics technologies that profile genes (genomic and epigenomic) and determine the abundance of mRNA (transcriptomic), protein (proteomic and secretomic), lipids (lipidomic), and extracellular matrix (matrisomic) support the dissection of ...
Giuliana Di Rocco   +3 more
doaj   +1 more source

Dynamic changes of immunocyte subpopulations in thermogenic activation of adipose tissues

open access: yesFrontiers in Immunology
ObjectivesThe effects of cold exposure on whole-body metabolism in humans have gained increasing attention. Brown or beige adipose tissues are crucial in cold-induced thermogenesis to dissipate energy and thus have the potential to combat metabolic ...
Yuqing Ye   +6 more
doaj   +1 more source

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