Results 1 to 10 of about 4,820,053 (311)
The SUMO E3 Ligase MdSIZ1 Sumoylates a Cell Number Regulator MdCNR8 to Control Organ Size [PDF]
Plant growth and organ size putatively associated with crop yield are regulated by a complex network of genes including ones for controlling cell proliferation.
Gui-Luan Wang +6 more
doaj +2 more sources
Neonatal corticosterone administration increases p27-positive Sertoli cell number and decreases Sertoli cell number in the testes of mice at prepuberty [PDF]
Cortisol and corticosterone (CORT) are steroid, antistress hormones and one of the glucocorticoids in humans and animals, respectively. This study evaluated the effects of CORT administration on the male reproductive system in early life stages. CORT was
Hidenobu Miyaso +10 more
doaj +2 more sources
ComProliM: A cell growth assay robust to initial cell number in co-culture system [PDF]
Cell growth is conventionally quantified using CCK-8 or MTT assays, but these methods display considerable sensitivity to initial cell quantities.
Yunda Song, MD, Subo Zhang, MD
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A cell number counting factor alters cell metabolism [PDF]
It is still not clear how organisms regulate the size of appendages or organs during development. During development, Dictyostelium discoideum cells form groups of ~2x104 cells. The cells secrete a protein complex called counting factor (CF) that allows
Wonhee Jang +2 more
doaj +3 more sources
The evolution of per-cell organelle number [PDF]
Organelles with their own distinct genomes, such as plastids and mitochondria, are found in most eukaryotic cells. As these organelles and their host cells have evolved, the partitioning of metabolic processes and the encoding of interacting gene ...
Logan W. Cole
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TOTAL CELL NUMBER IN FETAL BRAIN
In this study the material comprises brains from three aborted fetuses and two fullterm infants who died at birth.The gestational ages ranged from the 22nd week to term.
Grethe Badsberg Samuelsen +5 more
doaj +4 more sources
Timing the Landmark Events in the Evolution of Clear Cell Renal Cell Cancer: TRACERx Renal. [PDF]
Clear cell renal cell carcinoma (ccRCC) is characterized by near-universal loss of the short arm of chromosome 3, deleting several tumor suppressor genes. We analyzed whole genomes from 95 biopsies across 33 patients with clear cell renal cell carcinoma.
Raine, K +47 more
core +1 more source
Determinants of anti-PD-1 response and resistance in clear cell renal cell carcinoma [PDF]
ADAPTeR is a prospective, phase II study of nivolumab (anti-PD-1) in 15 treatment-naive patients (115 multiregion tumor samples) with metastatic clear cell renal cell carcinoma (ccRCC) aiming to understand the mechanism underpinning therapeutic response.
Schnidrig, D +59 more
core +1 more source
UQCRC1 engages cytochrome C for neuronal apoptotic cell death [PDF]
[[abstract]]Human ubiquinol-cytochrome c reductase core protein 1 (UQCRC1) is an evolutionarily conserved core subunit of mitochondrial respiratory chain complex III.
Hung, YC;Huang, KL;Chen, PL;Li, JL;Lu, SHA;Chang, JC;Lin, HY;Lo, WC;Huang, SY;Lee, TT;Lin, TY;Imai, Y;Hattori, N;Liu, CS;Tsai, SY;Chen, CH;Lin, CH;Chan, CC
core +1 more source
Large-fruit bud mutations are important factors in fruit tree breeding. However, little is known about the differences between varieties and bud mutations.
Jia Tian +5 more
doaj +1 more source

