Results 11 to 20 of about 4,820,053 (311)

De Novo Sequence and Copy Number Variants Are Strongly Associated with Tourette Disorder and Implicate Cell Polarity in Pathogenesis [PDF]

, 2018
We previously established the contribution of de novo damaging sequence variants to Tourette disorder (TD) through whole-exome sequencing of 511 trios. Here, we sequence an additional 291 TD trios and analyze the combined set of 802 trios.
천근아, 김은주, 송동호
core   +4 more sources

Ductal Ngn3-expressing progenitors contribute to adult β cell neogenesis in the pancreas [PDF]

, 2021
Ductal cells have been proposed as a source of adult β cell neogenesis, but this has remained controversial. By combining lineage tracing, 3D imaging, and single-cell RNA sequencing (scRNA-seq) approaches, we show that ductal cells contribute to the β ...
Rackham, Chloe, Lambert, C, Evans, Ian, Sancho, Rocio; id_orcid, Messal, Hendrik A., Jones, P, Hubber, Ella-louise, Messal, HA, Lambert, Christopher, Behrens, Axel, Heimberg, Harry, Hubber, E-L, Heimberg, H, Rackham, C, Jones, Peter; id_orcid, Evans, I, Gribben, C, Behrens, A, Gribben, Christopher, Sancho, R   +19 more
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Fruit shape loci sun, ovate, fs8.1 and their interactions affect seed size and shape in tomato

Frontiers in Plant Science, 2023
Seed size and shape are not only critical for plant reproduction and dispersal, but also important agronomic traits. Tomato fruit shape loci sun, ovate and fs8.1 regulate the morphology of fruit, flower, leaf and stem, and recently their functions in ...
Jie Chen, Jie Chen, Bingqing Pan, Bingqing Pan, Zixiong Li, Zixiong Li, Yue Xu, Yue Xu, Xiaomeng Cao, Xiaomeng Cao, Jingjing Jia, Jingjing Jia, Huolin Shen, Huolin Shen, Liang Sun, Liang Sun   +15 more
doaj   +1 more source

Meta-analysis of tumor- and T cell-intrinsic mechanisms of sensitization to checkpoint inhibition [PDF]

, 2021
Checkpoint inhibitors (CPIs) augment adaptive immunity. Systematic pan-tumor analyses may reveal the relative importance of tumor-cell-intrinsic and microenvironmental features underpinning CPI sensitization.
Turati, Virginia, Rosenthal, R, Saini, SK, Rosenthal, Rachel, Herrero, Javier, Rowan, A, Turajlic, Samra, Litchfield, K, Guerra-Assunção, José Afonso, Turajlic, S, Hellmann, Matthew D., Swanton, C, Saini, Sunil Kumar, Larkin, James, McGranahan, Nicholas, Reading, JL, Puttick, C, Reading, James L., Swanton, Charles, Thakkar, K, Al Bakir, M, Conde, L, Lim, Emilia, Watkins, TBK, Biswas, D, Enver, Tariq, Puttick, Clare, Turati, V, Litchfield, Kevin, Watkins, Thomas B.K., Hellmann, MD, Rowan, Andrew, Lim, E, Biswas, Dhruva, Van Loo, P, Quezada, SA, Guerra-Assunção, JA, Quezada, Sergio A., Bentham, Robert, Herrero, J, Enver, T, Furness, Andrew J.S., Hadrup, Sine R., Conde, Lucia, Hadrup, SR, Abbosh, C, Lee, Se Hoon, Furness, AJS, Lee, S-H, Al Bakir, Maise, Abbosh, Chris, McGranahan, N, Bentham, R, Larkin, J, Van Loo, Peter, Thakkar, Krupa   +55 more
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Non-linear Response to Cell Number Revealed and Eliminated From Long-Term Tracheid Measurements of Scots Pine in Southern Siberia

Frontiers in Plant Science, 2021
Dendroclimatic research offers insight into tree growth–climate response as a solution to the forward problem and provides reconstructions of climatic variables as products of the reverse problem. Methodological developments in dendroclimatology have led
Elena A. Babushkina, Dmitry R. Dergunov, Liliana V. Belokopytova, Dina F. Zhirnova, Keshav K. Upadhyay, Shri K. Tripathi, Mikhail S. Zharkov, Eugene A. Vaganov, Eugene A. Vaganov   +8 more
doaj   +1 more source

Cucumber Fruit Size and Shape Variations Explored from the Aspects of Morphology, Histology, and Endogenous Hormones

Plants, 2020
Fruit size and shape are important qualities and yield traits in cucumber (Cucumis sativus L.), but the factors that influence fruit size and shape remain to be explored. In this study, we investigated the dynamic changes of fruit size and shape from the
Xiaoxiao Liu, Yupeng Pan, Ce Liu, Yuanyuan Ding, Xiao Wang, Zhihui Cheng, Huanwen Meng   +6 more
doaj   +1 more source

Variable cell number in nematodes [PDF]

Nature, 1999
Studies of the nematode worm Caenorhabditis elegans have led to the widely held belief that individuals of a given nematode species are characterized by a property known as eutely, in which all individuals have the same total number of cells1. This property, which is peculiar to nematodes and a few other phyla, has raised the question of whether the ...
A, Cunha, R B, Azevedo, S W, Emmons, A M, Leroi   +3 more
openaire   +2 more sources

Changes in cell size and number and in rhizodermal development contribute to root tip swelling of Hyoscyamus albus roots subjected to iron deficiency [PDF]

, 2015
Root tip swelling is a common phenomenon observed when plant roots are subjected to Fe deficiency. We analysed whether an increase in cell number or an enlargement of cell width was involved in this phenomenon. Root tips of Hyoscyamus albus cultured with
Kawahara, Yuki, Kitamura, Yoshie
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Representation of uncertain multichannel digital signal spaces and study of pattern recognition based on metrics and difference values on fuzzy n-cell number spaces [PDF]

, 2009
In this paper, we discuss the problem of characterization for uncertain multichannel digital signal spaces, propose using fuzzy n-cell number space to represent uncertain n-channel digital signal space, and put forward a method of constructing such fuzzy
Shi, Peng, Wang, Guixiang, Messenger, P., Wang, G., Messenger, Paul, Shi, P.   +5 more
core   +1 more source

Intraoperative cell salvage: The impact on immune cell numbers

PLOS ONE, 2023
Background Patient outcomes are influenced by many confounding factors peri-operatively, including the type of surgery, anaesthesia, transfusion, and immune competence. We have previously demonstrated (in-vitro) that compared to allogeneic blood transfusion (ABT), intraoperative cell salvage (ICS) improves immune competence.
Michelle Roets, David Sturgess, Thu Tran, Maheshi Obeysekera, Alexis Perros, John-Paul Tung, Robert Flower, Andre van Zundert, Melinda Dean   +8 more
openaire   +5 more sources