A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome [PDF]
, 2021 [[abstract]]Endoplasmic reticulum (ER) dysregulation is associated with pathologies including neurodegenerative, muscular, and diabetic conditions. Depletion of ER calcium can lead to the loss of resident proteins in a process termed exodosis.
Henderson, MJ;Trychta, KA;Yang, SM;Bäck, S;Yasgar, A;Wires, ES;Danchik, C;Yan, X;Yano, H;Shi, L;Wu, KJ;Wang, AQ;Tao, D;Zahoránszky-Kőhalmi, G;Hu, X;Xu, X;Maloney, D;Zakharov, AV;Rai, G;Urano, F;Airavaara, M;Gavrilova, O;Jadhav, A;Wang, Y;Simeonov, A;Harvey, BK
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Cellularity of porcine adipose tissue: effects of growth and adiposity
Journal of Lipid Research, 1977 Adipose tissue, from two depots in pigs of three breeding groups with different propensities to fatten, was characterized in terms of weight of the adipose tissue organ, adipose cell number, and mean cell volume as determined by electronic counting of ...
R L Hood, C E Allen
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Effects of teicoplanin on cell number of cultured cell lines [PDF]
Interdisciplinary Toxicology, 2015 Abstract Teicoplanin is a glycopeptide antibiotic with a wide variation in human serum half-life. It is also a valuable alternative of vancomycin. There is however no study on its effect on cultured cells. The aim of the present study was to test the effect of teicoplanin on cultured cell lines CHO, Jurkat E6.1 and MCF-7.
Kashkolinejad-Koohi, Tahere +2 more
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Methods for the determination of adipose cell size in man and animals
Journal of Lipid Research, 1968 Four methods for the sizing of adipose cells in small samples of human or animal adipose tissue are compared. These methods depend on the preparation of cell suspensions by incubation of the tissue with collagenase or by prolonged fixation with osmium ...
Jules Hirsch, E. Gallian
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The FAM deubiquitylating enzyme localizes to multiple points of protein trafficking in epithelia, where it associates with E-cadherin and beta-catenin [PDF]
, 2004 Copyright © 2004 by The American Society for Cell Biology.Ubiquitylation is a necessary step in the endocytosis and lysosomal trafficking of many plasma membrane proteins and can also influence protein trafficking in the biosynthetic pathway.
Murray, Rachael +11 more
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Unbiased estimate of the epithelial cell number and epithelial cell nuclear volume in the bulbourethral (cowper) glands of holstein bulls - a stereological study [PDF]
Kafkas Universitesi Veteriner Fakültesi Dergisi, 2013 The bulbourethral gland (or Cowper"s gland) plays an important role for fertility. It is, therefore, essential to have quantitative data about the morphological and histomorphological structure of this gland in nonpathological conditions.
AKOSMAN MS +3 more
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Inflating Cell Numbers by Wnt [PDF]
Molecular Cell, 2002 One of the prominent biological phenomena controlled by Wnt signaling is the expansion of cells with predefined fates. In the November 27, 2002, issue of Cell, Rosenfeld and colleagues describe an example of Wnt-controlled proliferation during genesis of the cardiac outflow tract and the pituitary gland.
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Microtubule-Based Control of Motor-Clutch System Mechanics in Glioma Cell Migration [PDF]
, 2019 Microtubule-targeting agents (MTAs) are widely used chemotherapy drugs capable of disrupting microtubule-dependent cellular functions, such as division and migration.
Odde, David J. +6 more
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[[alternative]]Promiscuous binding of microprotein mozart1 to γ-tubulin complex mediates specific subcellular targeting to control microtubule array formation [PDF]
, 2020 [[abstract]]How γ-tubulin ring complex (γ-TuRC), a master template for microtubule nucleation, is spatially and temporally regulated for the assembly of new microtubule arrays remains unclear. Here, we report that an evolutionarily conserved microprotein,
Huang, TL;Wang, HJ;Chang, YC;Wang, SW;Hsia, KC
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Estimating merozoite release number and reinvasion efficiency in Plasmodium falciparum cell culture [PDF]
, 2021 During its asexual growth, Plasmodium falciparum undergoes a number of 48 h intra-erythrocytic cycles, punctuated by reinvasion events. The biomass formation dynamics can be described by three key parameters: the period of the growth cycle (for P ...
Snoep, J.L. +4 more
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