Ductal Ngn3-expressing progenitors contribute to adult β cell neogenesis in the pancreas
, 2021 Ductal cells have been proposed as a source of adult β cell neogenesis, but this has remained controversial. By combining lineage tracing, 3D imaging, and single-cell RNA sequencing (scRNA-seq) approaches, we show that ductal cells contribute to the β ...
Rackham, Chloe +29 more
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Methods for the determination of adipose cell size in man and animals
Journal of Lipid Research, 1968 Four methods for the sizing of adipose cells in small samples of human or animal adipose tissue are compared. These methods depend on the preparation of cell suspensions by incubation of the tissue with collagenase or by prolonged fixation with osmium ...
Jules Hirsch, E. Gallian
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SWI/SNF Complex Prevents Lineage Reversion and Induces Temporal Patterning in Neural Stem Cells [PDF]
, 2014 Members of the SWI/SNF chromatin-remodeling complex are among the most frequently mutated genes in human cancer, but how they suppress tumorigenesis is currently unclear.
Knoblich, Juergen A. +20 more
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Frontiers in Neuroanatomy, 2018 Estimation of total number of a population of cells that are sparsely distributed in an organ or anatomically-defined region of interest represents a challenge for conventional stereological methods.
Rogely W. Boyce, Hans J. G. Gundersen
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Cellularity of porcine adipose tissue: effects of growth and adiposity
Journal of Lipid Research, 1977 Adipose tissue, from two depots in pigs of three breeding groups with different propensities to fatten, was characterized in terms of weight of the adipose tissue organ, adipose cell number, and mean cell volume as determined by electronic counting of ...
R L Hood, C E Allen
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Cdc42-mediated tubulogenesis controls cell specification. [PDF]
, 2009 SummaryUnderstanding how cells polarize and coordinate tubulogenesis during organ formation is a central question in biology. Tubulogenesis often coincides with cell-lineage specification during organ development. Hence, an elementary question is whether
Greiner, Thomas +18 more
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p57(Kip2) imposes the reserve stem cell state of gastric chief cells
, 2022 Adult stem cells constantly react to local changes to ensure tissue homeostasis. In the main body of the stomach, chief cells produce digestive enzymes; however, upon injury, they undergo rapid proliferation for prompt tissue regeneration.
Ju, Young Seok +47 more
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A mechanical G2 checkpoint controls epithelial cell division through E-cadherin-mediated regulation of Wee1-Cdk1 [PDF]
, 2022 Epithelial cell divisions are coordinated with cell loss to preserve epithelial integrity. However, how epithelia adapt their rate of cell division to changes in cell number, for instance during homeostatic turnover or wounding, is not well understood ...
Gómez González, Manuel +28 more
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Unbiased estimate of the epithelial cell number and epithelial cell nuclear volume in the bulbourethral (cowper) glands of holstein bulls - a stereological study [PDF]
Kafkas Universitesi Veteriner Fakültesi Dergisi, 2013 The bulbourethral gland (or Cowper"s gland) plays an important role for fertility. It is, therefore, essential to have quantitative data about the morphological and histomorphological structure of this gland in nonpathological conditions.
AKOSMAN MS +3 more
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The FAM deubiquitylating enzyme localizes to multiple points of protein trafficking in epithelia, where it associates with E-cadherin and beta-catenin [PDF]
, 2004 Copyright © 2004 by The American Society for Cell Biology.Ubiquitylation is a necessary step in the endocytosis and lysosomal trafficking of many plasma membrane proteins and can also influence protein trafficking in the biosynthetic pathway.
Murray, Rachael +8 more
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