Results 151 to 160 of about 268,511 (302)

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Unified Brain Mechanisms Underlying the Processing of Word Order Permutations of Arguments and Adjuncts in Sentences. [PDF]

Hum Brain Mapp
Asami D, Naoe T, Makuuchi M, Koizumi M.
europepmc   +1 more source

[Adjunct Temple]

, 1978
Photograph of an adjunct temple in the Yakushiji Temple Complex of Nara, Japan. In the foreground, two stone lanterns (ishidoros) are visible. The temple is visible behind the lanterns.
Gough, Ray
core  

Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma

Molecular Oncology, EarlyView.
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara, Kosuke Murakami, Shiro Takamatsu, Akiko Kanto, Seiichi Mori, Tomoyuki Otani, Kazuko Sakai, Yasushi Kotani, Kazuto Nishio, Kaoru Abiko, Noriomi Matsumura   +10 more
wiley   +1 more source

Intrathecal immune checkpoint inhibitors as adjunctive therapy for leptomeningeal disease: A case series and systematic review. [PDF]

Neurosurg Rev
Daftari M, Ramsoomair CK, Aka A, Himic V, Hudson A, Berckemeyer MA, Johnson M, Lu VM, Chandar J, Govindrajan V, Lutzky J, Ivan ME, Komotar RJ, Nasany R, Shah AH.   +14 more
europepmc   +1 more source

Adjunctions

, 1994
We present the category-theoretic notion of adjunction in a way that makes it easy to formally <i>calculate</i> with it; an acquaintance with its algebraic properties may greatly help in understanding the notion. It is illustrated by means of a lot of theorems and proofs.
Fokkinga, M.M., Meertens, Lambert
openaire   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Beyond Recanalization: A Mechanistic and Procedural Framework for Adjunct Pharmacologic Therapy During Mechanical Thrombectomy. [PDF]

J Clin Med
Shaikh S, Raslan TT, Tanweer A, Nasir Z, Siraj H, Raziq T, Shoukat U, Mavrych V, Bolgova O, Yaqinuddin A.   +9 more
europepmc   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

The Adjunctive Applications of Integra® in Free-Flap Surgery to the Scalp: A Two-Case Experience

International Medical Case Reports Journal
James C Yuen,1 Elizabeth N Dawson,2 Connor S Miller,3 Madalyn H Bowman,2 Aimee A Tran2 1Division of Plastic Surgery, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA; 2College of Medicine, University of Arkansas for Medical ...
Yuen JC, Dawson EN, Miller CS, Bowman MH, Tran AA   +4 more
doaj