Results 111 to 120 of about 1,198,663 (392)

Adjuvant Therapy: Melanoma [PDF]

open access: yesJournal of Skin Cancer, 2011
With an incidence that is increasing at 2–5% per year, cutaneous melanoma is an international scourge that disproportionately targets young individuals. Despite much research, the treatment of advanced disease is still quite challenging. Immunotherapy with high-dose interferon-α2b or interleukin-2 benefits a select group of patients in the adjuvant and
Diwakar Davar   +2 more
openaire   +3 more sources

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner   +6 more
wiley   +1 more source

The adjuvant effect of Gantrez®AN nanoparticles on oral vaccination of pigs and mice with F4 fimbriae is strongly influenced by polymer degradation [PDF]

open access: yes, 2011
We analysed the adjuvant effect of Gantrez nanoparticles NP on oral immunisation of pigs and mice with F4 fimbriae. The animals were vaccinated with F4, F4 encapsulated in Gantrez NP, called gF4 NP, or F4 + empty Gantrez NP, called F4 + gNP, and ...
Cox, Eric   +4 more
core   +1 more source

Lung adjuvant cisplatin evaluation: a pooled analysis by the LACE Collaborative Group.

open access: yesJournal of Clinical Oncology, 2008
PURPOSE Several recent trials have shown a significant overall survival (OS) benefit from postoperative cisplatin-based chemotherapy in patients with non-small-cell lung cancer (NSCLC).
J. Pignon   +16 more
semanticscholar   +1 more source

PORTEC-4a: international randomized trial of molecular profile-based adjuvant treatment for women with high-intermediate risk endometrial cancer

open access: yesInternational Journal of Gynecological Cancer, 2020
Background Vaginal brachytherapy is currently recommended as adjuvant treatment in patients with high-intermediate risk endometrial cancer to maximize local control and has only mild side effects and no or limited impact on quality of life.
A. S. V. M. van den Heerik   +29 more
semanticscholar   +1 more source

A DIA‐MS‐based proteomics approach to find potential serum prognostic biomarkers in glioblastoma patients

open access: yesMolecular Oncology, EarlyView.
A DIA‐MS‐based proteomics analysis of serum samples from GB patients and healthy controls showed that high levels of IL1R2 and low levels of CRTAC1 and HRG in serum are associated with poor survival outcomes for GB patients. These circulating proteins could serve as biomarkers for the prediction of outcome in patients with GB.
Anne Clavreul   +11 more
wiley   +1 more source

Alternatives to mineral oil adjuvants in vaccines against Aeromonas salmonicida subsp. salmonicida in rainbow trout offer reductions in adverse effects

open access: yesScientific Reports, 2017
In an effort to reduce the frequency and severity of adverse reactions seen from the use of mineral oil adjuvants in salmonid fish, the effects of two alternative adjuvants were assessed, focusing on the induction of adverse effects as well as protection.
Kasper Rømer Villumsen   +3 more
doaj   +1 more source

Successful role of adjuvant radiotherapy in a rare case of tracheal inflammatory myofibroblastic tumor: a case report [PDF]

open access: yes, 2019
BACKGROUND:: Inflammatory myofibroblastic tumor (IMT) is a rare benign cancer that can express a more aggressive phenotype related to the genetic mutation of the anaplastic lymphoma kinase receptor (ALK). Involvement of trachea is extremely rare and due
Abate, Gessica   +7 more
core   +1 more source

Tailoring Adjuvant Endocrine Therapy for Premenopausal Breast Cancer

open access: yesNew England Journal of Medicine, 2018
BACKGROUND In the Suppression of Ovarian Function Trial (SOFT) and the Tamoxifen and Exemestane Trial (TEXT), the 5‐year rates of recurrence of breast cancer were significantly lower among premenopausal women who received the aromatase inhibitor ...
P. Francis   +35 more
semanticscholar   +1 more source

A bi-adjuvant nanovaccine that potentiates immunogenicity of neoantigen for combination immunotherapy of colorectal cancer

open access: yesScience Advances, 2020
A rationally designed bi-adjuvant nanovaccine enhances neoantigen immunogenicity and enables combination immunotherapy. Neoantigen vaccines have been enthusiastically pursued for personalized cancer immunotherapy while vast majority of neoantigens have ...
Qianqian Ni   +11 more
semanticscholar   +1 more source

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