Results 211 to 220 of about 1,250,673 (409)

746 CpG Island Methylator Phenotype May Confer a Survival Benefit From Fluoropyrimidine-Based Adjuvant Chemotherapy on Patients With Stage II or III Colorectal Carcinomas

open access: bronze, 2010
Young Kyung Sung   +6 more
openalex   +1 more source

Bimetallic Nanoreactor Activates cGAS‐STING Pathway via mtDNA Release for Cancer Metalloimmunotherapy

open access: yesAdvanced Functional Materials, EarlyView.
A bimetallic Mn–Ca nanoreactor (MCC) is developed as a non‐nucleotide STING nanoagonist for cancer metalloimmunotherapy. MCC induces Ca2+ overload and hydroxyl radical generation, resulting in mitochondrial damage and mtDNA release. The released mtDNA cooperates with Mn2+ to robustly activate cGAS–STING signaling.
Xin Wang Mo   +7 more
wiley   +1 more source

The uncoupling effect of the nonsteroidal anti‐inflammatory drug nimesulide in liver mitochondria from adjuvant‐induced arthritic rats [PDF]

open access: bronze, 2001
Silvana Martins Caparroz‐Assef   +5 more
openalex   +1 more source

Synergistic Compatibilization of CsPbBr3 Perovskites and HfO2 Nanocrystals for Hybrid Sensitized Nanoscintillators

open access: yesAdvanced Functional Materials, EarlyView.
Lead halide perovskite nanocrystals are promising scintillators but suffer from reabsorption losses and limited compatibility with high‐Z additives. Hybridization of CsPbBr3 nanocrystals with PbBr2‐passivated HfO2 nanoparticle sensitizers, achieved during or after synthesis, produces stable composites with maintained optical quality, improved ...
Francesco Bruni   +17 more
wiley   +1 more source

Pitfalls of Using the Cockcroft-Gault Formula When Calculating Carboplatin Dose for the Adjuvant Treatment of Patients with Stage i Seminoma

open access: bronze, 2012
Martin Fehr   +9 more
openalex   +1 more source

A Single‐Metal‐Doped Nanoplatform for Ferroptosis‐Driven cGAS‐STING Pathway Activation in Hepatocellular Carcinoma Immunotherapy

open access: yesAdvanced Functional Materials, EarlyView.
The cGAS‐STING pathway boosts HCC antitumor immunity but lacks specific activation. Nanoplatform ZMRPF induces HCC ferroptosis via lipid ROS, releasing mtDNA. It synergizes with ZMRPF‐released Mn2⁺ to activate cGAS‐STING, amplifies antigen‐presenting cell activity, reverses HCC immunosuppression, and enables robust systemic antitumor immunity ...
Yuchen Zhang   +13 more
wiley   +1 more source

Actionable driver gene alterations in early-stage non-small cell lung cancer: a review. [PDF]

open access: yesTher Adv Med Oncol
Attili I   +9 more
europepmc   +1 more source

Adjuvant Dabrafenib plus Trametinib in Stage III BRAF‐Mutated Melanoma

open access: yesNew England Journal of Medicine, 2017
G. Long   +22 more
semanticscholar   +1 more source

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