Results 21 to 30 of about 950,946 (355)

An empirical approach towards the efficient and optimal production of influenza-neutralizing ovine polyclonal antibodies demonstrates that the novel adjuvant CoVaccine HT(TM) is functionally superior to Freund's adjuvant [PDF]

, 2013
Passive immunotherapies utilising polyclonal antibodies could have a valuable role in preventing and treating infectious diseases such as influenza, particularly in pandemic situations but also in immunocompromised populations such as the elderly, the ...
A Kourti, AF Ochsenbein, AG Blom, AR Newcombe, C Cresswell, C Newcombe, Cara K. Fraser, CK Fraser, D Corti, DK Hong, E Klechevsky, FC Jensen, FW Santiago, G Jego, GA McMillin, H Ogonuki, H Ueno, J Aucouturier, J Guan, J Hinkula, J Thatte, J Ye, JA Turkstra, JC Cox, JD Berry, JE McElhaney, John D. Hayball, JT Wu, Kerrilyn R. Diener, L Sjostrom, L Vidard, LM Grant, M Baz, M Leenaars, M Mahdi Abdel Hamid, M Singh, MF Patria, Michael P. Brown, MJ Lynch, Mohammed Alsharifi, MR Buckwalter, Natalie E. Stevens, PR Dormitzer, R Bodewes, R Bodewes, RJ Scibienski, RM Redwan el, RM Zinkernagel, S Chhatre, S Martin-Gomez, SC de Cassan, SH van Ierssel, SJ Draper, T Suda, TT Wang, Valerie A. Ferro, W Luytjes, WC Ng, Y Mine, YT Chang   +59 more
core   +3 more sources

Adjuvant treatment [PDF]

HPB, 2006
Exocrine pancreatic cancer (pancreatic ductal adenocarcinoma) is one of the leading causes of cancer deaths in the western world, accounting for 5% of all cancer-related deaths. Only a small percentage of patients with pancreatic cancer are able to undergo potentially curative resection, even in specialized centres, and prognosis remains poor after ...
Sultana, Asma, Neoptolemos, John, Ghaneh, Paula   +2 more
openaire   +2 more sources

Cyclic GMP-AMP Triggers Asthma in an IL-33-Dependent Manner That Is Blocked by Amlexanox, a TBK1 Inhibitor

Frontiers in Immunology, 2019
Extracellular host-derived DNA, as one of damage associated molecular patterns (DAMPs), is associated with allergic type 2 immune responses. Immune recognition of such DNA generates the second messenger cyclic GMP-AMP (cGAMP) and induces type-2 immune ...
Koji Ozasa, Koji Ozasa, Burcu Temizoz, Burcu Temizoz, Burcu Temizoz, Burcu Temizoz, Takato Kusakabe, Takato Kusakabe, Takato Kusakabe, Shingo Kobari, Shingo Kobari, Masatoshi Momota, Masatoshi Momota, Cevayir Coban, Cevayir Coban, Cevayir Coban, Shuichi Ito, Kouji Kobiyama, Kouji Kobiyama, Kouji Kobiyama, Kouji Kobiyama, Etsushi Kuroda, Etsushi Kuroda, Etsushi Kuroda, Ken J. Ishii, Ken J. Ishii, Ken J. Ishii, Ken J. Ishii, Ken J. Ishii   +28 more
doaj   +1 more source

Adjuvant Activity of Synthetic Lipid A of Alcaligenes, a Gut-Associated Lymphoid Tissue-Resident Commensal Bacterium, to Augment Antigen-Specific IgG and Th17 Responses in Systemic Vaccine

Vaccines, 2020
Alcaligenes spp. are identified as commensal bacteria and have been found to inhabit Peyer’s patches in the gut. We previously reported that Alcaligenes-derived lipopolysaccharides (LPS) exerted adjuvant activity in systemic vaccination, without ...
Yunru Wang, Koji Hosomi, Atsushi Shimoyama, Ken Yoshii, Haruki Yamaura, Takahiro Nagatake, Tomomi Nishino, Hiroshi Kiyono, Koichi Fukase, Jun Kunisawa   +9 more
doaj   +1 more source

Adherence to adjuvant therapy in post-menopausal breast cancer patients: A review [PDF]

, 2011
This is the post-print version of the Article. The official published version can be accessed from the link below - Copyright @ 2012 John Wiley & Sons, IncThis review aimed to address the concept of adherence to adjuvant therapy in post-menopausal women.
Banning, M
core   +1 more source

Adjuvant-containing control arms in pivotal quadrivalent human papillomavirus vaccine trials: Restoration of previously unpublished methodology [PDF]

, 2020
Purpose: Trustworthy reporting of quadrivalent human papillomavirus (HPV) vaccine trials is the foundation for assessing the vaccine's risks and benefits.
Bourgeois, Florence, Doshi, Peter, Hong, Kyungwan, Jefferson, Tom, Jones, Mark, Lee, Haeyoung, Shamseer, Larissa, Spence, O'Mareen   +7 more
core   +1 more source

DAMP-Inducing Adjuvant and PAMP Adjuvants Parallelly Enhance Protective Type-2 and Type-1 Immune Responses to Influenza Split Vaccination

Frontiers in Immunology, 2018
Recently, it was reported that 2-hydroxypropyl-β-cyclodextrin (HP-β-CyD), a common pharmaceutical additive, can act as a vaccine adjuvant to enhance protective type-2 immunogenicity to co-administered seasonal influenza split vaccine by inducing host ...
Tomoya Hayashi, Tomoya Hayashi, Masatoshi Momota, Masatoshi Momota, Etsushi Kuroda, Etsushi Kuroda, Takato Kusakabe, Takato Kusakabe, Shingo Kobari, Kotaro Makisaka, Yoshitaka Ohno, Yoshitaka Ohno, Yusuke Suzuki, Fumika Nakagawa, Michelle S. J. Lee, Cevayir Coban, Risako Onodera, Taishi Higashi, Keiichi Motoyama, Ken J. Ishii, Ken J. Ishii, Hidetoshi Arima, Hidetoshi Arima   +22 more
doaj   +1 more source

The role of adjuvant chemotherapy for patients with resected pancreatic cancer: Systematic review of randomized controlled trials and meta-analysis [PDF]

, 2007
Background: In patients undergoing surgery for resectable pancreatic cancer prognosis still remains poor. The role of adjuvant treatment strategies (including chemotherapy and chemoradiotherapy) following resection of pancreatic cancer remains ...
Bakkevold KE, Berger AC, Blackstock AW, Cress RD, Donna Pauler Ankerst, Gastrointestinal Tumour Study Group, Hochster HS, Kalser MH, Khanna A, Knaebel HP, Kosuge T, Luttges J, Oettle H, Ozols RF, Peto R, Regine WF, Stefan Boeck, Volker Heinemann   +17 more
core   +1 more source

17(S),18(R)‐epoxyeicosatetraenoic acid generated by cytochrome P450 BM‐3 from Bacillus megaterium inhibits the development of contact hypersensitivity via G‐protein‐coupled receptor 40‐mediated neutrophil suppression

FASEB BioAdvances, 2020
Dietary intake of ω3 polyunsaturated fatty acids such as eicosapentaenoic acid and docosahexaenoic acid is beneficial for health control. We recently identified 17,18‐epoxyeicosatetraenoic acid (17,18‐EpETE) as a lipid metabolite endogenously generated ...
Azusa Saika, Takahiro Nagatake, Shigenobu Kishino, Si‐Bum Park, Tetsuya Honda, Naomi Matsumoto, Michiko Shimojou, Sakiko Morimoto, Prabha Tiwari, Eri Node, So‐ichiro Hirata, Koji Hosomi, Kenji Kabashima, Jun Ogawa, Jun Kunisawa   +14 more
doaj   +1 more source

Prognostic value of lymph node ratio and extramural vascular invasion on survival for patients undergoing curative colon cancer resection [PDF]

, 2015
There was no study funding. We are grateful to Tony Rafferty (Tailored Information for the People of Scotland, TIPs) for providing survival data.Peer reviewedPublisher ...
A Bhangu, A de Gramont, A O’Shea, A Sternberg, AC Berger, C MacKay, C N Parnaby, ED Courtney, F Cianchi, G I Murray, G Ramsay, GT Williams, H Ueno, HK Choi, J Betge, J Lykke, J Wang, L Bui, L Samuel, L Schiffmann, LH Sobin, M A Loudon, M Morris, N W Scott, NN Baxter, OH Sjo, P Quirke, R Rosenberg, R Rosenberg, SJ Moug, SL Chen, W Hohenberger   +31 more
core   +2 more sources