Results 61 to 70 of about 1,198,663 (392)
Diffusion MR Characteristics Following Concurrent Radiochemotherapy Predicts Progression-Free and Overall Survival in Newly Diagnosed Glioblastoma. [PDF]
, 2015 The standard of care for newly diagnosed glioblastoma (GBM) is surgery, then radiotherapy (RT) with concurrent temozolomide (TMZ), followed by adjuvant TMZ. We hypothesized patients with low diffusivity measured using apparent diffusion coefficient (ADC)
Chang, Warren +9 more
core +1 more source
Vaccines, 2021 Opioid use disorder (OUD) is a serious health problem that has dramatically increased over the last decade. Although current therapies for the management of OUD can be effective, they have limitations.
Essie Komla +8 more
doaj +1 more source
Drug Discovery Today: Technologies, 2020 Carbohydrate adjuvants are safe and biocompatible compounds usable as sustained delivery systems and stimulants of ongoing humoral and cellular immune responses, being especially suitable for the development of vaccines against intracellular pathogens where alum is useless.
Garcia-Vello, Pilar +4 more
openaire +6 more sources
Dendritic cells steering antigen and leukocyte traffic in lymph nodes
FEBS Letters, EarlyView.Dendritic cells are key players in the activation of T cells and their commitment to effector function. In this In a Nutshell Review, we will discuss how dendritic cells guide the trafficking of antigen and leukocytes in the lymph node, thus influencing T‐cell activation processes. Dendritic cells (DCs) play a central role in initiating and shaping the
Enrico Dotta +3 more
wiley +1 more source
Dendritic cell proliferation by primary cilium in atopic dermatitis
Frontiers in Molecular Biosciences, 2023 Introduction: Atopic dermatitis (AD) is a common allergic eczema that affects up to 10% of adults in developed countries. Immune cells in the epidermis, namely, Langerhans cells (LCs), contribute to the pathogenesis of AD, although their exact role(s) in
Manami Toriyama +19 more
doaj +1 more source
Effect of adjuvants on the efficiency of benthiavalicarb plus mancozeb (Valbon 1.6 kg/ha) on the control of late blight in potato [PDF]
, 2009 Industrial adjuvants were tested in combination with benthiavalicarb plus mancozeb (Valbon 1.6 kg/ha) in the field to investigate their efficacy on foliar late blight caused by Phytophthora infestans.
De Schampheleire, Mieke +6 more
core +1 more source
Antigen depot is not required for alum adjuvanticity [PDF]
, 2012 Alum adjuvants have been in continuous clinical use for more than 80 yr. While the prevailing theory has been that depot formation and the associated slow release of antigen and/or inflammation are responsible for alum enhancement of antigen presentation
Abigail H. Pollock +11 more
core +2 more sources
Expert Review of Vaccines, 2007 Adjuvants are substances that boost the immunogenicity of vaccines. However, most successful vaccines have been derived empirically and are capable of inducing robust T- and B-cell immunity without any adjuvant additives. Emerging evidence suggests that such live vaccines induce innate immune activation via a range of stimuli, including ligands ...
Bali Pulendran +2 more
openaire +3 more sources
Autophagy in cancer and protein conformational disorders
FEBS Letters, EarlyView.Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley +1 more source
Frontiers in Immunology, 2017 Macrophages are a major target for human immunodeficiency virus type 1 (HIV-1) infection. However, macrophages are largely heterogeneous and may exhibit differences in permissiveness to HIV-1 infection.
Ousman Jobe +9 more
doaj +1 more source