Results 71 to 80 of about 1,250,673 (409)
Integration of circadian and hypoxia signaling via non‐canonical heterodimerization
FEBS Letters, EarlyView.CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley +1 more source
mAbs, 2021 The prevalence and societal impact of opioid use disorder (OUD) is an acknowledged public health crisis that is further aggravated by the current pandemic. One of the devastating consequences of OUD is opioid overdose deaths.
Bhupal Ban +12 more
doaj +1 more source
JAMA Oncology, 2019 Importance Adjuvant chemotherapy in patients with stage III colon cancer prevents recurrence by eradicating minimal residual disease. However, which patients remain at high risk of recurrence after completing standard adjuvant treatment cannot currently ...
J. Tie +23 more
semanticscholar +1 more source
Prognostic value of lymph node ratio and extramural vascular invasion on survival for patients undergoing curative colon cancer resection [PDF]
, 2015 There was no study funding. We are grateful to Tony Rafferty (Tailored Information for the People of Scotland, TIPs) for providing survival data.Peer reviewedPublisher ...
A Bhangu +31 more
core +2 more sources
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
ENDOSCOPIC THIRD VENTRICULOSTOMY IN THE TREATMENT OF NORMOTENSIVE HYDROCEPHALUS. A CLINICAL CASE
Клінічна та профілактична медицинаIntroduction. Normotensive hydrocephalus is an abnormal accumulation of cerebrospinal fluid in the ventricles of the brain. This causes an increase in the enlargement of the ventricles and an increase in intracranial pressure.
Orest I. Palamar +4 more
doaj +1 more source
Primary Cilia in the Skin: Functions in Immunity and Therapeutic Potential
Frontiers in Cell and Developmental Biology, 2021 The skin is the biggest organ and provides a physical and immunological barrier against pathogen infection. The distribution of primary cilia in the skin of mice has been reported, but which cells in human skin have them has not, and we still know very ...
Manami Toriyama +5 more
doaj +1 more source
Effect of adjuvants on the efficiency of dimethomorph plus mancozeb (Acrobat 2 kg:ha) on the control of late blight [PDF]
, 2007 Industrial adjuvants were tested in combination with dimethomorph plus mancozeb (Acrobat 2 kg/ha) in the field to investigate their efficacy on foliar late blight caused by Phytophthora infestans.
Haesaert, Geert +6 more
core +1 more source
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
Frontiers in Pharmacology, 2021 We previously identified Alcaligenes spp. as a commensal bacterium that resides in lymphoid tissues, including Peyer’s patches. We found that Alcaligenes-derived lipopolysaccharide acted as a weak agonist of Toll-like receptor four due to the unique ...
Zilai Liu +30 more
doaj +1 more source